Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Audrey Desgrange"'
2
Akademický článek
Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages
Autor: Audrey Desgrange, Johanna Lokmer, Carmen Marchiol, Lucile Houyel, Sigolène M. Meilhac
Publikováno v: Disease Models & Mechanisms, Vol 12, Iss 7 (2019)
Laterality defects are developmental disorders resulting from aberrant left/right patterning. In the most severe cases, such as in heterotaxy, they are associated with complex malformations of the heart. Advances in understanding the underlying physi
Externí odkaz: https://doaj.org/article/b4b6f473277c4946941bd4a30584a194
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3
Akademický článek
Nephron Patterning: Lessons from Xenopus, Zebrafish, and Mouse Studies
Autor: Audrey Desgrange, Silvia Cereghini
Publikováno v: Cells, Vol 4, Iss 3, Pp 483-499 (2015)
The nephron is the basic structural and functional unit of the vertebrate kidney. To ensure kidney functions, the nephrons possess a highly segmental organization where each segment is specialized for the secretion and reabsorption of particular solu
Externí odkaz: https://doaj.org/article/57ff8bf3467542e680262debfa465a24
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4
Akademický článek
A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics
Autor: Jean-François Le Garrec, Jorge N Domínguez, Audrey Desgrange, Kenzo D Ivanovitch, Etienne Raphaël, J Andrew Bangham, Miguel Torres, Enrico Coen, Timothy J Mohun, Sigolène M Meilhac
Publikováno v: eLife, Vol 6 (2017)
How left-right patterning drives asymmetric morphogenesis is unclear. Here, we have quantified shape changes during mouse heart looping, from 3D reconstructions by HREM. In combination with cell labelling and computer simulations, we propose a novel
Externí odkaz: https://doaj.org/article/4f3a99d7fac64740a1cd302a855eaa78
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5
Pseudodynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left–right asymmetry
Autor: Isaac Esteban, Patrick Schmidt, Audrey Desgrange, Morena Raiola, Susana Temiño, Sigolène M. Meilhac, Leif Kobbelt, Miguel Torres
Publikováno v: Nature Cardiovascular Research
Nature Cardiovascular Research, 2022, 1, pp.504-517. ⟨10.1038/s44161-022-00065-1⟩
Nature cardiovascular research 1(5), 504-517 (2022). doi:10.1038/s44161-022-00065-1 special issue: "Intestinal endothelium and stem cell cross-talk"
Nature cardiovascular research 1(5), 504-517 (2022). doi:10.1038/s44161-022-00065-1 special issue: "Intestinal endothelium and stem cell cross-talk"
Published by Nature Publishing Group UK, London
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc30329ed6b812264932fe8c9e2d081a
https://hal-pasteur.archives-ouvertes.fr/pasteur-03851032
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6
Transient Nodal Signaling in Left Precursors Coordinates Opposed Asymmetries Shaping the Heart Loop
Autor: Jean-François Le Garrec, Sigolène M. Meilhac, Ségolène Bernheim, Audrey Desgrange, Tobias Holm Bønnelykke
Publikováno v: Developmental Cell
Developmental Cell, 2020, 55 (4), pp.413-431.e6. ⟨10.1016/j.devcel.2020.10.008⟩
Developmental Cell, Elsevier, 2020, 55 (4), pp.413-431.e6. ⟨10.1016/j.devcel.2020.10.008⟩
SummaryThe secreted factor Nodal has been shown to be a major left determinant. Although it is associated with severe congenital heart defects, its role in heart morphogenesis has remained poorly understood. Here, we report that Nodal is transiently
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc528ee6aa13c8f442353577ab1e40a
https://hal.science/hal-03094810/file/S153458072030798X.pdf
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7
A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics
Autor: Audrey Desgrange, Kenzo Ivanovitch, Timothy J. Mohun, Miguel Torres, Enrico Coen, Jorge N. Domínguez, Sigolène M. Meilhac, Jean-François Le Garrec, Etienne Raphaël, J. Andrew Bangham
Publikováno v: eLife
eLife, eLife Sciences Publication, 2017, 6, ⟨10.7554/eLife.28951⟩
eLife, 2017, 6, ⟨10.7554/eLife.28951⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
eLife, Vol 6 (2017)
How left-right patterning drives asymmetric morphogenesis is unclear. Here, we have quantified shape changes during mouse heart looping, from 3D reconstructions by HREM. In combination with cell labelling and computer simulations, we propose a novel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2736d6f5f28b3c2316e23cd930822b5b
https://hal.archives-ouvertes.fr/hal-03094757/file/elife-28951-v2.pdf
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10
Novel fixed z-direction (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging
Autor: Ilya Skovorodkin, Veli-Pekka Ronkainen, Seppo Vainio, Saad Ullah Akram, Silvia Cereghini, Jingdong Shan, Audrey Desgrange, Aleksandra Rak-Raszewska, Janne Heikkilä, Ulla Saarela
Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), 2017, 144 (6, SI), pp.1113-1117. ⟨10.1242/dev.142950⟩
Development (Cambridge, England), Company of Biologists, 2017, 144 (6, SI), pp.1113-1117. ⟨10.1242/dev.142950⟩
International audience; Tissue, organ and organoid cultures provide suitable models for developmental studies, but our understanding of how the organs are assembled at the single-cell level still remains unclear. We describe here a novel fixed z-dire
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1d3ec8160054d26a78b42325785a57
https://hal.science/hal-01539793
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