Výsledky vyhledávání - "Audrey Chissey"

Akademický článek

A Glyphosate-Based Formulation but Not Glyphosate Alone Alters Human Placental Integrity

Autor: Christelle Simasotchi, Audrey Chissey, Gérald Jungers, Thierry Fournier, Gilles-Eric Seralini, Sophie Gil

Publikováno v: Toxics, Vol 9, Iss 9, p 220 (2021)

Glyphosate (G)-based herbicidal formulations, such as the most commonly used one, Roundup (R), are major pesticides used worldwide on food and feed. Pregnant women may be frequently exposed to R compounds. These are composed of G, which is declared a

Externí odkaz: https://doaj.org/article/3928aa89e7ae420ca613837bf398a3d2

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Akademický článek

Human Placental NADPH Oxidase Mediates sFlt-1 and PlGF Secretion in Early Pregnancy: Exploration of the TGF-β1/p38 MAPK Pathways

Autor: Isabelle Hernandez, Audrey Chissey, Jean Guibourdenche, Roger Atasoy, Xavier Coumoul, Thierry Fournier, Jean-Louis Beaudeux, Amal Zerrad-Saadi

Publikováno v: Antioxidants, Vol 10, Iss 2, p 281 (2021)

Preeclampsia, a hypertensive disorder occurring during pregnancy, is characterized by excessive oxidative stress and trophoblast dysfunction with dysregulation of soluble Fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF) producti

Externí odkaz: https://doaj.org/article/d6a4076f3fdf416b81ff0cba45c78aca

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Akademický článek

Uptake of Cerium Dioxide Nanoparticles and Impact on Viability, Differentiation and Functions of Primary Trophoblast Cells from Human Placenta

Autor: Margaux Nedder, Sonja Boland, Stéphanie Devineau, Amal Zerrad-Saadi, Jasmina Rogozarski, René Lai-Kuen, Ibtissem Baya, Jean Guibourdenche, Francoise Vibert, Audrey Chissey, Sophie Gil, Xavier Coumoul, Thierry Fournier, Ioana Ferecatu

Publikováno v: Nanomaterials, Vol 10, Iss 7, p 1309 (2020)

The human placenta is at the interface between maternal and fetal circulations, and is crucial for fetal development. The nanoparticles of cerium dioxide (CeO2 NPs) from air pollution are an unevaluated risk during pregnancy. Assessing the consequenc

Externí odkaz: https://doaj.org/article/57bab637800445c886bad12c4cfc712a

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Akademický článek

Liposomes as Gene Delivery Vectors for Human Placental Cells

Autor: Lucie Valero, Khair Alhareth, Jenifer Espinoza Romero, Warren Viricel, Jeanne Leblond, Audrey Chissey, Hélène Dhotel, Caroline Roques, Danielle Campiol Arruda, Virginie Escriou, Nathalie Mignet, Thierry Fournier, Karine Andrieux

Publikováno v: Molecules, Vol 23, Iss 5, p 1085 (2018)

Nanomedicine as a therapeutic approach for pregnancy-related diseases could offer improved treatments for the mother while avoiding side effects for the fetus. In this study, we evaluated the potential of liposomes as carriers for small interfering R

Externí odkaz: https://doaj.org/article/35e7ec9186e647339cdfbc0fcd711722

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16 Biological Effects of Benzo-[A]-Pyrene and Cerium Nanoparticles on the Human Placental Barrier

Autor: Gaëlle Deval, Séverine Degrelle, Sonja Boland, Stéphanie Devineau, Marie-Leone Vignaud, Jasmina Rogozarski, Audrey Chissey, Adrian Mrozik, Didier Borderie, Thierry Fournier, Amal Zerrad-Saadi, Ioana Ferecatu

Publikováno v: Annals of Work Exposures and Health. 67:i44-i44

The human placenta is a transitory organ essential for fetal development, whose functions can be disrupted by xenobiotics in maternal blood. Benzo-[a]-pyrene (B[a]P) is a carcinogenic, mutagenic and reprotoxic pollutant as well as an endocrine disrup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c70cc07890e043703d3d83467a97130
https://doi.org/10.1093/annweh/wxac087.107

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Benzo(a)pyrene and Cerium Dioxide Nanoparticles in Co-Exposure Impair Human Trophoblast Cell Stress Signaling

Autor: Gaëlle Deval, Margaux Nedder, Séverine Degrelle, Jasmina Rogozarski, Marie-Léone Vignaud, Audrey Chissey, Stacy Colzin, Christelle Laguillier-Morizot, Xavier Coumoul, Sonja Boland, Thierry Fournier, Amal Zerrad-Saadi, Ioana Ferecatu

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5439

Human placenta is a multifunctional interface between maternal and fetal blood. Studying the impact of pollutants on this organ is crucial because many xenobiotics in maternal blood can accumulate in placental cells or pass into the fetal circulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c1320ea8dfc16a86ac829ad63dba20
https://doi.org/10.3390/ijms24065439

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NADPH oxidase is the major source of placental superoxide in early pregnancy: association with MAPK pathway activation

Autor: Thierry Fournier, Jean-Louis Beaudeux, Amal Zerrad-Saadi, Patrice Thérond, Audrey Chissey, Isabelle Hernandez, Abdel Slama

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports

First-trimester placenta (2 pressure (12–14 GW), the activities of the antioxidant enzymes SOD1, catalase and GPX1 are increased. The redox-sensitive MAPK pathways show increased phosphorylated-p38 expression, but no variation in the phosphorylatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b57cc99374f5e94bec1f628424c5035
http://link.springer.com/article/10.1038/s41598-019-50417-4

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Influence of Liposomes’ and Lipoplexes’ Physicochemical Characteristics on Their Uptake Rate and Mechanisms by the Placenta

Autor: Louise Fliedel, Khair Alhareth, Johanne Seguin, Marwa El-Khashab, Audrey Chissey, Nathalie Mignet, Thierry Fournier, Karine Andrieux

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6299
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (11), pp.6299. ⟨10.3390/ijms23116299⟩

International audience; Pregnant women are still considered as drug orphans. Developing new medications for pregnancy complications is an urgent need. Nanomedicines seem to be a promising approach to control the biodistribution of drugs to ensure bot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcf315832f1d52b289f65abab922721
https://doi.org/10.3390/ijms23116299

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Human Placental NADPH Oxidase Mediates sFlt-1 and PlGF Secretion in Early Pregnancy: Exploration of the TGF-β1/p38 MAPK Pathways

Autor: Audrey Chissey, Jean Guibourdenche, Roger Atasoy, Thierry Fournier, Amal Zerrad-Saadi, Xavier Coumoul, Beaudeux Jl, Isabelle Hernandez

Publikováno v: Antioxidants
Volume 10
Issue 2
Antioxidants, Vol 10, Iss 281, p 281 (2021)
Antioxidants, 2021, 10 (2), pp.281. ⟨10.3390/antiox10020281⟩

International audience; Preeclampsia, a hypertensive disorder occurring during pregnancy, is characterized by excessive oxidative stress and trophoblast dysfunction with dysregulation of soluble Fms-like tyrosine kinase 1 (sFlt-1) and placental growt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2c3b9d90513f9baaef083afc261211
http://europepmc.org/articles/PMC7918586

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Mining of combined human placental gene expression data across pregnancy, applied to PPAR signaling pathway

Autor: Wencan Zhu, Séverine A. Degrelle, Thierry Fournier, Audrey Chissey, Fulin Liu, Hussein Shoaito

Publikováno v: Placenta
Placenta, Elsevier, 2020, 99, pp.157-165. ⟨10.1016/j.placenta.2020.07.024⟩

Introduction To date, we have only an incomplete understanding of how gene expression in the human placenta changes at the genome-wide scale from very early in gestation to term. Our aim was to investigate the dynamic changes in gene expression throu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6accf9589c87115053b20bafed083497
https://hal.archives-ouvertes.fr/hal-03492479

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