Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Audrey C. Papp"'
Publikováno v:
BioTechniques, Vol 34, Iss 5, Pp 1068-1072 (2003)
We present a PCR method for identification of single nucleotide polymorphisms (SNPs), using allele-specific primers designed for selective amplification of each allele. Matching the SNP at the 3′ end of the forward or reverse primer, and additional
Externí odkaz:
https://doaj.org/article/23e5ca15f2864f6ea388a484a039c04f
Autor:
Audrey C Papp, Abul K Azad, Maciej Pietrzak, Amanda Williams, Samuel K Handelman, Robert P Igo, Catherine M Stein, Katherine Hartmann, Larry S Schlesinger, Wolfgang Sadee
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198221 (2018)
Human alveolar macrophages (HAM) are primary bacterial niche and immune response cells during Mycobacterium tuberculosis (M.tb) infection, and human blood monocyte-derived macrophages (MDM) are a model for investigating M.tb-macrophage interactions.
Externí odkaz:
https://doaj.org/article/e28290c5f68e46aa883fa2d95c42d8e0
Autor:
Evelyn Guirado Caceres, Larry S. Schlesinger, Elliott D. Crouser, Van T Le, Mark W. Julian, Landon W. Locke, Audrey C. Papp, Wolfgang Sadee, Peter White
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 60:84-95
The mechanisms underlying abnormal granuloma formation in patients with sarcoidosis are complex and remain poorly understood. A novel in vitro human granuloma model was used to determine the molecu...
Autor:
Brian E Roe, Michael R Tilley, Howard H Gu, David Q Beversdorf, Wolfgang Sadee, Timothy C Haab, Audrey C Papp
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6704 (2009)
With recent advances in understanding of the neuroscience of risk taking, attention is now turning to genetic factors that may contribute to individual heterogeneity in risk attitudes. In this paper we test for genetic associations with risk attitude
Externí odkaz:
https://doaj.org/article/8883ad2eff964b0aa766464698b89663
Autor:
Larry S. Schlesinger, Audrey C. Papp, Landon W. Locke, Elliott D. Crouser, Peter White, Mark W. Julian, Evelyn Guirado Caceres, Wolfgang Sadee
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 57:487-498
Many aspects of pathogenic granuloma formation are poorly understood, requiring new relevant laboratory models that represent the complexity (genetics and diversity) of human disease. To address this need, we developed an in vitro model of granuloma
Publikováno v:
European Journal of Pharmaceutical Sciences. 103:47-51
The blood-brain barrier (BBB) expresses numerous membrane transporters that supply needed nutrients to the central nervous system (CNS), consisting mostly of solute carriers (SLC transporters), or remove unwanted substrates via extrusion pumps throug
Autor:
Audrey C. Papp, Yan Guo, Jianqi Yang, Takayuki Shiomi, Isabel Cunningham, Rory A. Fisher, Bandana Chakravarti, Yu Shyr, Diane Hamele-Bena
Publikováno v:
American journal of hematologyREFERENCES. 94(11)
Recent studies of leukemic tumors in individual extramedullary sites showed they adopt the clinical and metastatic behavior of solid cancers originating in those sites. To elucidate features of leukemic tumors that render them resistant to agents eff
Autor:
Amanda Curtis, Wolfgang Sadee, Audrey C. Papp, Douglas W. Scharre, Grzegorz A. Rempala, Maciej Pietrzak, Maria Kataki, Samuel K. Handelman
Publikováno v:
Biochemical and Biophysical Research Communications. 479:875-880
Dementia with Lewy Bodies (DLB) is the second most common neurodegenerative disorder in the elderly. The development and progression of DLB remain unclear. In this study we used next generation sequencing to assess RNA expression profiles and cellula
Publikováno v:
Pharmacogenetics and Genomics. 25:394-401
BACKGROUND Cholesteryl ester transfer protein (CETP) is involved in reverse cholesterol transport by exchanging cholesteryl esters for triglycerides between high-density lipoprotein and low-density lipoprotein particles, effectively decreasing high-d
Autor:
Wolfgang Sadee, Daren L. Knoell, Abul K. Azad, Charlie J. Pyle, Audrey C. Papp, Larry S. Schlesinger
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2375 (2017)
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2375 (2017)
Tuberculosis (TB) is a global epidemic caused by the infection of human macrophages with the world’s most deadly single bacterial pathogen, Mycobacterium tuberculosis (M.tb). M.tb resides in a phagosomal niche within macrophages, where trace elemen