Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Audrey C Papp"'
Autor:
Audrey C Papp, Abul K Azad, Maciej Pietrzak, Amanda Williams, Samuel K Handelman, Robert P Igo, Catherine M Stein, Katherine Hartmann, Larry S Schlesinger, Wolfgang Sadee
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198221 (2018)
Human alveolar macrophages (HAM) are primary bacterial niche and immune response cells during Mycobacterium tuberculosis (M.tb) infection, and human blood monocyte-derived macrophages (MDM) are a model for investigating M.tb-macrophage interactions.
Externí odkaz:
https://doaj.org/article/e28290c5f68e46aa883fa2d95c42d8e0
Autor:
Roshan Mascarenhas, Maciej Pietrzak, Ryan M Smith, Amy Webb, Danxin Wang, Audrey C Papp, Julia K Pinsonneault, Michal Seweryn, Grzegorz Rempala, Wolfgang Sadee
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136798 (2015)
mRNA translation into proteins is highly regulated, but the role of mRNA isoforms, noncoding RNAs (ncRNAs), and genetic variants remains poorly understood. mRNA levels on polysomes have been shown to correlate well with expressed protein levels, poin
Externí odkaz:
https://doaj.org/article/034eadc90dc14c379ab2f79d10520787
Autor:
Audrey C Papp, Julia K Pinsonneault, Danxin Wang, Leslie C Newman, Yan Gong, Julie A Johnson, Carl J Pepine, Meena Kumari, Aroon D Hingorani, Philippa J Talmud, Sonia Shah, Steve E Humphries, Wolfgang Sadee
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31930 (2012)
Polymorphisms in and around the Cholesteryl Ester Transfer Protein (CETP) gene have been associated with HDL levels, risk for coronary artery disease (CAD), and response to therapy. The mechanism of action of these polymorphisms has yet to be defined
Externí odkaz:
https://doaj.org/article/e6846031eab348b5a7925fc31e4fa446
Autor:
Brian E Roe, Michael R Tilley, Howard H Gu, David Q Beversdorf, Wolfgang Sadee, Timothy C Haab, Audrey C Papp
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6704 (2009)
With recent advances in understanding of the neuroscience of risk taking, attention is now turning to genetic factors that may contribute to individual heterogeneity in risk attitudes. In this paper we test for genetic associations with risk attitude
Externí odkaz:
https://doaj.org/article/8883ad2eff964b0aa766464698b89663
Autor:
Evelyn Guirado Caceres, Larry S. Schlesinger, Elliott D. Crouser, Van T Le, Mark W. Julian, Landon W. Locke, Audrey C. Papp, Wolfgang Sadee, Peter White
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 60:84-95
The mechanisms underlying abnormal granuloma formation in patients with sarcoidosis are complex and remain poorly understood. A novel in vitro human granuloma model was used to determine the molecu...
Autor:
Larry S. Schlesinger, Audrey C. Papp, Landon W. Locke, Elliott D. Crouser, Peter White, Mark W. Julian, Evelyn Guirado Caceres, Wolfgang Sadee
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 57:487-498
Many aspects of pathogenic granuloma formation are poorly understood, requiring new relevant laboratory models that represent the complexity (genetics and diversity) of human disease. To address this need, we developed an in vitro model of granuloma
Publikováno v:
European Journal of Pharmaceutical Sciences. 103:47-51
The blood-brain barrier (BBB) expresses numerous membrane transporters that supply needed nutrients to the central nervous system (CNS), consisting mostly of solute carriers (SLC transporters), or remove unwanted substrates via extrusion pumps throug
Autor:
Audrey C. Papp, Yan Guo, Jianqi Yang, Takayuki Shiomi, Isabel Cunningham, Rory A. Fisher, Bandana Chakravarti, Yu Shyr, Diane Hamele-Bena
Publikováno v:
American journal of hematologyREFERENCES. 94(11)
Recent studies of leukemic tumors in individual extramedullary sites showed they adopt the clinical and metastatic behavior of solid cancers originating in those sites. To elucidate features of leukemic tumors that render them resistant to agents eff
Autor:
Amanda Curtis, Wolfgang Sadee, Audrey C. Papp, Douglas W. Scharre, Grzegorz A. Rempala, Maciej Pietrzak, Maria Kataki, Samuel K. Handelman
Publikováno v:
Biochemical and Biophysical Research Communications. 479:875-880
Dementia with Lewy Bodies (DLB) is the second most common neurodegenerative disorder in the elderly. The development and progression of DLB remain unclear. In this study we used next generation sequencing to assess RNA expression profiles and cellula
Publikováno v:
Pharmacogenetics and Genomics. 25:394-401
BACKGROUND Cholesteryl ester transfer protein (CETP) is involved in reverse cholesterol transport by exchanging cholesteryl esters for triglycerides between high-density lipoprotein and low-density lipoprotein particles, effectively decreasing high-d