Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Audrey Baguette"'
Autor:
Melissa Zwaig, Audrey Baguette, Bo Hu, Michael Johnston, Hussein Lakkis, Emily M. Nakada, Damien Faury, Nikoleta Juretic, Benjamin Ellezam, Alexandre G. Weil, Jason Karamchandani, Jacek Majewski, Mathieu Blanchette, Michael D. Taylor, Marco Gallo, Claudia L. Kleinman, Nada Jabado, Jiannis Ragoussis
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Juvenile Pilocytic Astrocytomas (JPAs) are one of the most common pediatric brain tumors, and they are driven by aberrant activation of the mitogen-activated protein kinase (MAPK) signaling pathway. RAF-fusions are the most common
Externí odkaz:
https://doaj.org/article/4381905f37b94a1eb20515d76b4091cd
Autor:
Christophe Tav, Éric Fournier, Michèle Fournier, Fatemeh Khadangi, Audrey Baguette, Maxime C. Côté, Maruhen A. D. Silveira, Félix-Antoine Bérubé-Simard, Guillaume Bourque, Arnaud Droit, Steve Bilodeau
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Transcription-factor binding to cis-regulatory regions regulates the gene expression program of a cell, but occupancy is often a poor predictor of the gene response. Here, we show that glucocorticoid stimulation led to the reorganization of transcrip
Externí odkaz:
https://doaj.org/article/46a0e08edf1d4f4bbd95e182c99dc81e
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across more than 10,000 adult and pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741da86f253c6e42c0401531e9509b90
https://doi.org/10.1158/0008-5472.c.6514136.v1
https://doi.org/10.1158/0008-5472.c.6514136.v1
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c77d20498973705d006fee266ee01a
https://doi.org/10.1158/0008-5472.22432439.v1
https://doi.org/10.1158/0008-5472.22432439.v1
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b86034115df2220900de572ba0818
https://doi.org/10.1158/0008-5472.22432385
https://doi.org/10.1158/0008-5472.22432385
Autor:
Jessica W. Tsai, Paloma Cejas, Marissa Coppola, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P. Dubois, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Annarah Charles, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Volker Hovestadt, Claudia Kleinman, Henry Long, David T. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Research. 83:3562-3562
Background: Diffuse midline gliomas (DMGs) are a universally fatal brain tumor of childhood. While histone mutations are a critical tumor initiating event, they are insufficient to drive gliomagenesis. Histone mutations co-occur with somatic alterati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d55b572d6d64893013f01366528f7ed
https://doi.org/10.1158/1538-7445.am2023-3562
https://doi.org/10.1158/1538-7445.am2023-3562
FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
Autor:
Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P.B. Dubois, Alexander Crane, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, François Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Volker Hovestadt, Claudia L. Kleinman, Henry Long, David T.W. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Res
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across more than 10,000 adult and pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b04fde1eafeb27aba2cd478be2c63a8
https://europepmc.org/articles/PMC9437574/
https://europepmc.org/articles/PMC9437574/
Autor:
Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P. Dubois, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Claudia Kleinman, Henry Long, David T. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Research. 82:5730-5730
Background: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology. Forkhead box (FOX) proteins are a superfamily of transcriptional regulators characterized by a fork
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf770cb8febb799d1dfd12cdab65b172
https://doi.org/10.1158/1538-7445.am2022-5730
https://doi.org/10.1158/1538-7445.am2022-5730
Autor:
Jessica W Tsai, Paloma Cejas, Dayle K Wang, Smruti Patel, David W Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P B Dubois, Alexander Crane, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L Condurat, Sarah E Dixon-Clarke, Kevin N Zhou, Sophie D Lu, Elizabeth M Gonzalez, Madison S Chacon, Jeromy J Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J Baker, Jinghui Zhang, James M McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M Pfister, Keith L Ligon, Claudia L Kleinman, Henry Long, David T W Jones, Pratiti Bandopadhayay, Timothy N Phoenix
BACKGROUND: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology. Forkhead box (FOX) proteins are a superfamily of transcriptional regulators characterized by a fork
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d62d7fc7e751a4d28899955a247a5d
Autor:
Frank Dubois, Ofer Shapira, Noah Greenwald, Travis Zack, Jeremiah Wala, Jessica Tsai, Alexander Crane, Audrey Baguette, Djihad Hadjadj, Ashot Harutyunyan, Kiran Kumar, Mirjam Blattner-Johnson, Jayne Vogelzang, Cecilia Sousa, Kyung Shin Kang, Claire Sinai, Dayle Wang, Prasidda Khadka, Hayley Malkin, Patricia Ho, Ryan O'Rourke, Shu Zhang, Rose Gold, Davy Deng, Jonathan Serrano, Matija Snuderl, Chris Jones, Karen Wright, Susan Chi, Jacques Grill, Claudia Kleinman, Liliana Goumnerova, Nada Jabado, David Jones, Mark Kieran, Keith Ligon, Rameen Beroukhim, Pratiti Bandopadhayay
Publikováno v:
Neuro-Oncology. 24:i75-i76
Pediatric high-grade gliomas (pHGGs), encompassing hemispheric and diffuse midline gliomas (DMGs), remain a devastating disease. The last decade has revealed oncogenic drivers including single nucleotide variants (SNVs) in histones. However, the cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63aed46ffd772188ffdb70dbcdac28e6
https://doi.org/10.1093/neuonc/noac079.275
https://doi.org/10.1093/neuonc/noac079.275