Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Audrey A. O'Neill"'
Autor:
Terren K. Niethamer, Andrew R. Larson, Audrey K. O’Neill, Marina Bershteyn, Edward C. Hsiao, Ophir D. Klein, Jason H. Pomerantz, Jeffrey O. Bush
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 529-537 (2017)
Although human induced pluripotent stem cells (hiPSCs) hold great potential for the study of human diseases affecting disparate cell types, they have been underutilized in seeking mechanistic insights into the pathogenesis of congenital craniofacial
Externí odkaz:
https://doaj.org/article/fd30d514e8f0484a83b89035b904b324
Autor:
Audrey G O’Neill, Anika L Burrell, Michael Zech, Orly Elpeleg, Tamar Harel, Simon Edvardson, Hagar Mor Shaked, Alyssa L Rippert, Tomoki Nomakuchi, Kosuke Izumi, Justin M Kollman
Publikováno v:
bioRxiv
Inosine 5’ monophosphate dehydrogenase (IMPDH) is a critical regulatory enzyme in purine nucleotide biosynthesis that is inhibited by the downstream product GTP. Multiple point mutations in the human isoform IMPDH2 have recently been associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9193d0be8d04f82e75c69af528335290
https://europepmc.org/articles/PMC10055058/
https://europepmc.org/articles/PMC10055058/
Publikováno v:
Nano LIFE. 12
Dexamethasone is a synthetic corticosteroid that has historically been used to treat inflammation, such as from osteoarthritis, spinal cord injury and, more recently, COVID-19. The mechanism of action of dexamethasone is generally known to include at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0292c7414c25926df28b1651009a89b
https://doi.org/10.1142/s1793984422300035
https://doi.org/10.1142/s1793984422300035
Publikováno v:
Appl Environ Microbiol
Soil bacteria can detoxify Cr(VI) ions by reduction. Within the last 2 decades, numerous reports of chromate reductase enzymes have been published. These reports describe catalytic reduction of chromate ions by specific enzymes. These enzymes each ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ac7ba3d1dee2cfb5deb765f54afc12
https://europepmc.org/articles/PMC7642083/
https://europepmc.org/articles/PMC7642083/
Autor:
Terren K. Niethamer, Audrey K. O’Neill, Jeffrey O. Bush, Andrew R. Larson, Hsin-Yi Henry Ho, Abigail A. Kindberg, Michael E. Greenberg
Publikováno v:
The Journal of cell biology, vol 215, iss 2
The Journal of Cell Biology
The Journal of Cell Biology
Eph/ephrins drive cell segregation and boundary formation. O’Neill et al. discover that segregation is driven by unidirectional kinase-dependent EphB signaling. Unidirectional signaling generates a cortical actin differential between ephrin-B1– a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a6303d6d91ca03987c89406a4e6752
https://doi.org/10.1083/jcb.201604097
https://doi.org/10.1083/jcb.201604097
Autor:
Jeffrey O. Bush, Audrey K. O’Neill
Publikováno v:
Epstein's Inborn Errors of Development: The Molecular Basis of Clinical Disorders of Morphogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8824d173027fc12675158a282048f4db
https://doi.org/10.1093/med/9780199934522.003.0086
https://doi.org/10.1093/med/9780199934522.003.0086
Publikováno v:
FEBS Journal. 280:572-583
The recently discovered pleckstrin homology (PH) domain leucine-rich repeat protein phosphatase (PHLPP) family is emerging as a central component in suppressing cell survival pathways. Originally discovered in a rational search for a phosphatase that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4f3edfbdf267bcf618a662ba398822
https://doi.org/10.1111/j.1742-4658.2012.08537.x
https://doi.org/10.1111/j.1742-4658.2012.08537.x
Autor:
Audrey Myerson O'Neill
Publikováno v:
Journal of Applied Research in Intellectual Disabilities. 24:566-572
Background This longitudinal study of 20 average and bright adults with parents with cognitive difficulties follows a study 20 years earlier of their childhood adaptation to their parents. Method Semistructured interviews about life situation and cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00045ea6a3190e5745e4202c7def1de3
https://doi.org/10.1111/j.1468-3148.2011.00631.x
https://doi.org/10.1111/j.1468-3148.2011.00631.x
Publikováno v:
Journal of Neurochemistry. 100:1340-1350
Biosynthesis of peptide hormones and neurotransmittters involves proteolysis of proprotein precursors by secretory vesicle cathepsin L. Cathepsin L generates peptide intermediates with basic residues at their NH2-termini, indicating that Arg/Lys amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927274ed3ef351af82ac1d00a8ae1a4f
https://doi.org/10.1111/j.1471-4159.2006.04325.x
https://doi.org/10.1111/j.1471-4159.2006.04325.x
Publikováno v:
Developmental biology, vol 379, iss 2
The Wnt1-Cre transgenic mouse line is extensively used in the study of the development of the neural crest and its derivatives and the midbrain. The Wnt1 gene has important developmental roles in formation of the midbrain–hindbrain boundary, regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd592c35903c803b1a9bbea02b790d33
https://pubmed.ncbi.nlm.nih.gov/23648512
https://pubmed.ncbi.nlm.nih.gov/23648512