Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Audrey, Sirvent"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The tumor microenvironment facilitates cancer progression and therapeutic resistance. Tumor collagens and their architecture play an essential role in this process. However, little is known about the mechanisms by which tumor cells sense and respond
Externí odkaz:
https://doaj.org/article/72e27be2633244d4979fc6cce662a8eb
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Colorectal cancer (CRC) is one of the leading causes of tumor-related death worldwide. While surgery can cure patients with early stage CRC, the 5-year survival rate is only 10% for patients with metastatic disease. Therefore, new anti-metastatic the
Externí odkaz:
https://doaj.org/article/3e6e6a88776d43d196264073a97f399b
Autor:
Maya Jeitany, Cédric Leroy, Priscillia Tosti, Marie Lafitte, Jordy Le Guet, Valérie Simon, Debora Bonenfant, Bruno Robert, Fanny Grillet, Caroline Mollevi, Safia El Messaoudi, Amaëlle Otandault, Lucile Canterel‐Thouennon, Muriel Busson, Alain R Thierry, Pierre Martineau, Julie Pannequin, Serge Roche, Audrey Sirvent
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 4, Pp 1-16 (2018)
Abstract The clinical management of metastatic colorectal cancer (mCRC) faces major challenges. Here, we show that nilotinib, a clinically approved drug for chronic myeloid leukaemia, strongly inhibits human CRC cell invasion in vitro and reduces the
Externí odkaz:
https://doaj.org/article/c79f020dc047450c9db38f20c405e854
Autor:
Bruno Robert, Christel Larbouret, André Pèlegrin, Jean-Max Pasquet, Dany Chalbos, Charles Theillet, Nina Radosevic-Robin, Marta Jarlier, Muriel Busson, Imade Aït-Arsa, Audrey Sirvent, Clément Chevalier, Stanislas du Manoir, Myriam Chentouf, Wilhem Leconet
Supplementary Figure 1. AXL, MER and TYRO-3 expression in Triple Negative Breast Cancer (TNBC) cell lines and PDXs by Western blot analysis. Supplementary Figure 2. AXL mRNA expression in a large dataset of breast cancer tumors. Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023a6dc180a6d199242c3f56b2350681
https://doi.org/10.1158/1078-0432.22461975
https://doi.org/10.1158/1078-0432.22461975
Autor:
Bruno Robert, Christel Larbouret, André Pèlegrin, Jean-Max Pasquet, Dany Chalbos, Charles Theillet, Nina Radosevic-Robin, Marta Jarlier, Muriel Busson, Imade Aït-Arsa, Audrey Sirvent, Clément Chevalier, Stanislas du Manoir, Myriam Chentouf, Wilhem Leconet
Suppl.Table 1: Analysis of the cellular localization, pathways and gene expression modification of the 100 genes most correlated with AXL expression in 254 basal-like breast cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635155602a6aa74a17415c756f8d5c63
https://doi.org/10.1158/1078-0432.22461969.v1
https://doi.org/10.1158/1078-0432.22461969.v1
Autor:
Bruno Robert, Christel Larbouret, André Pèlegrin, Jean-Max Pasquet, Dany Chalbos, Charles Theillet, Nina Radosevic-Robin, Marta Jarlier, Muriel Busson, Imade Aït-Arsa, Audrey Sirvent, Clément Chevalier, Stanislas du Manoir, Myriam Chentouf, Wilhem Leconet
Purpose: AXL receptor tyrosine kinase has been described as a relevant molecular marker and a key player in invasiveness, especially in triple-negative breast cancer (TNBC).Experimental Design: We evaluate the antitumor efficacy of the anti-AXL monoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab178ad928c1e3fe9b0a52f7ac1582dd
https://doi.org/10.1158/1078-0432.c.6524970.v1
https://doi.org/10.1158/1078-0432.c.6524970.v1
Autor:
Serge Roche, Patrick Jouin, Bruno Robert, Joël Poncet, Serge Urbach, Valérie Simon, Audrey Sirvent, Camille Fialin, Cédric Leroy
The nonreceptor tyrosine kinase Src is frequently overexpressed and/or activated in human colorectal carcinoma (CRC), and its increased activity has been associated with a poor clinical outcome. Src has been implicated in growth and invasion of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::402fa6a429b60cc19e63d77ee34a2bc8
https://doi.org/10.1158/0008-5472.c.6499608.v1
https://doi.org/10.1158/0008-5472.c.6499608.v1
Autor:
Serge Roche, Patrick Jouin, Bruno Robert, Joël Poncet, Serge Urbach, Valérie Simon, Audrey Sirvent, Camille Fialin, Cédric Leroy
Supplementary Figure 1 from Quantitative Phosphoproteomics Reveals a Cluster of Tyrosine Kinases That Mediates Src Invasive Activity in Advanced Colon Carcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab635a1a8e8c4baf215487bf7d37d10
https://doi.org/10.1158/0008-5472.22380579
https://doi.org/10.1158/0008-5472.22380579
Autor:
Serge Roche, Patrick Jouin, Bruno Robert, Joël Poncet, Serge Urbach, Valérie Simon, Audrey Sirvent, Camille Fialin, Cédric Leroy
Supplementary Table 1 from Quantitative Phosphoproteomics Reveals a Cluster of Tyrosine Kinases That Mediates Src Invasive Activity in Advanced Colon Carcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08370527142f0a5f41e070e88fa0f264
https://doi.org/10.1158/0008-5472.22380576.v1
https://doi.org/10.1158/0008-5472.22380576.v1
Publikováno v:
Molecular & Cellular Oncology, Vol 5, Iss 4 (2018)
The clinical management of metastatic colorectal cancer (mCRC) is still a major challenge. Recently, we discovered that nilotinib, an approved treatment for chronic myeloid leukaemia, inhibits invasive and metastatic properties of CRC cells by target
Externí odkaz:
https://doaj.org/article/f723639e92de496aa43465b831e22ae4