Tecovirimat Resistance in Mpox Patients, United States, 2022–2023

Autor: Todd G. Smith, Crystal M. Gigante, Nhien T. Wynn, Audrey Matheny, Whitni Davidson, Yong Yang, Rene Edgar Condori, Kyle O’Connell, Lynsey Kovar, Tracie L. Williams, Yon C. Yu, Brett W. Petersen, Nicolle Baird, David Lowe, Yu Li, Panayampalli S. Satheshkumar, Christina L. Hutson

Publikováno v: Emerging Infectious Diseases, Vol 29, Iss 12, Pp 2426-2432 (2023)

During the 2022 multinational outbreak of monkeypox virus (MPXV) infection, the antiviral drug tecovirimat (TPOXX; SIGA Technologies, Inc., https://www.siga.com) was deployed in the United States on a large scale for the first time. The MPXV F13L gen

Externí odkaz: https://doaj.org/article/9a123816218646aabeb63e8826093b2a

Orthopoxvirus Infections in Rodents, Nigeria, 2018–2019

Autor: Clement Meseko, Adeyinka Adedeji, Ismaila Shittu, Emmanuel Obishakin, Maurice Nanven, Ladan Suleiman, Daniel Okomah, Visa Tyakaray, Damilola Kolade, Adesola Yinka-Ogunleye, Saleh Muhammad, Clint N. Morgan, Audrey Matheny, Yoshinori Nakazawa, Andrea McCollum, Jeffrey B. Doty

Publikováno v: Emerging Infectious Diseases, Vol 29, Iss 2, Pp 433-434 (2023)

To investigate animal reservoirs of monkeypox virus in Nigeria, we sampled 240 rodents during 2018–2019. Molecular (real-time PCR) and serologic (IgM) evidence indicated orthopoxvirus infections, but presence of monkeypox virus was not confirmed. T

Externí odkaz: https://doaj.org/article/fcc7f7335fad4e9b96efafdd4115fed3

Rapid Diagnostic Testing for Response to the Monkeypox Outbreak — Laboratory Response Network, United States, May 17–June 30, 2022

Autor: Tricia A, Aden, Patricia, Blevins, Shannon Whitman, York, Stacy, Rager, Devika, Balachandran, Christina L, Hutson, David, Lowe, Chris N, Mangal, Tyler, Wolford, Audrey, Matheny, Whitni, Davidson, Kimberly, Wilkins, Rachael, Cook, Rebecca M, Roulo, Michael K, White, LaShondra, Berman, Janna, Murray, John, Laurance, Drew, Francis, Nicole M, Green, Ricardo A, Berumen, Anthony, Gonzalez, Stacy, Evans, Meghan, Hudziec, Diane, Noel, Michael, Adjei, Gregory, Hovan, Phil, Lee, Lisa, Tate, Remedios B, Gose, Robert, Voermans, Jennifer, Crew, Phillip R, Adam, Danielle, Haydel, Salimatu, Lukula, Nick, Matluk, Sandip, Shah, Joshua, Featherston, Daphne, Ware, Denise, Pettit, Emily, McCutchen, Edward, Acheampong, Erin, Buttery, Andrew, Gorzalski, Michael, Perry, Randal, Fowler, Robert B, Lee, Robert, Nickla, Richard, Huard, Amanda, Moore, Katie, Jones, Renee, Johnson, Erin, Swaney, Juan, Jaramillo, Cynthia, Reinoso Webb, Brandon, Guin, Janine, Yost, Annette, Atkinson, Latoya, Griffin-Thomas, Jessica, Chenette, Jessica, Gant, Alana, Sterkel, Harjinder K, Ghuman, James, Lute, Sandra C, Smole, Vaneet, Arora, Courtney K, Demontigny, Meilan, Bielby, Evelyn, Geeter, Kimberly A M, Newman, Mark, Glazier, Whitney, Lutkemeier, Megan, Nelson, Raymond, Martinez, Jasmine, Chaitram, Margaret A, Honein, Julie M, Villanueva

Publikováno v: MMWR. Morbidity and Mortality Weekly Report. 71:904-907

As part of public health preparedness for infectious disease threats, CDC collaborates with other U.S. public health officials to ensure that the Laboratory Response Network (LRN) has diagnostic tools to detect Orthopoxviruses, the genus that include

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57dfb1abf521876c794c0d56ae3c5b57
https://doi.org/10.15585/mmwr.mm7128e1

Genomic deletions and rearrangements in monkeypox virus from the 2022 outbreak, USA

Autor: Crystal M. Gigante, Matthew Plumb, Ali Ruprecht, Hui Zhao, Vaughn Wicker, Kimberly Wilkins, Audrey Matheny, Theodora Khan, Whitni Davidson, Mili Sheth, Alex Burgin, Mark Burroughs, Jasmine Padilla, Justin S. Lee, Dhwani Batra, Ethan E. Hetrick, Dakota T. Howard, Jacob Garfin, Lisa Tate, Shan J. Hubsmith, Rafael M. Mendoza, Danielle Stanek, Sarah Gillani, Michelle Lee, Anil Mangla, David Blythe, Sean SierraPatev, Kristin Carpenter-Azevedo, Richard C. Huard, Glen Gallagher, Joshua Hall, Stephanie Ash, Lynsey Kovar, Matthew H. Seabolt, Michael R. Weigand, Inger Damon, Panayampalli S. Satheshkumar, Andrea M. McCollum, Christina L. Hutson, Xiong Wang, Yu Li

Genomic surveillance of monkeypox virus (MPXV) during the 2022 outbreak has been mainly focused on single nucleotide polymorphism (SNP) changes. DNA viruses, including MPXV, have a lower SNP mutation rate than RNA viruses due to higher fidelity repli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5763fefc70cca8ab547dbfdbe8312eb
https://doi.org/10.1101/2022.09.16.508251