Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Audre May"'
Autor:
Justin A. Guerrero, Dorota D. Klysz, Yiyun Chen, Meena Malipatlolla, Jameel Lone, Carley Fowler, Lucille Stuani, Audre May, Malek Bashti, Peng Xu, Jing Huang, Basil Michael, Kévin Contrepois, Shaurya Dhingra, Chris Fisher, Katrin J. Svensson, Kara L. Davis, Maya Kasowski, Steven A. Feldman, Elena Sotillo, Crystal L. Mackall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The intensive nutrient requirements needed to sustain T cell activation and proliferation, combined with competition for nutrients within the tumor microenvironment, raise the prospect that glucose availability may limit CAR-T cell function.
Externí odkaz:
https://doaj.org/article/83e1ea5811734dc0b264ba4b71908511
Autor:
Grace X.Y. Zheng, Somya Khare, Brendan Galvin, Robby Moot, Aaron Cooper, Michelle Nguyen, Michelle Tan, Shan Sabri, Audre May, Jun Fung, Anzhi Yao, Andrea Liu, Matt Drever, Steve Santoro, W Nicholas Haining, Tarjei Mikkelsen
Publikováno v:
Cancer Research. 82:2840-2840
T cell therapies for cancer have shown striking clinical efficacy in different tumor settings. Integration of a transgene cassette expressing an antigen receptor into the genome enables T cells to recognize specific tumor antigens. Viral vectors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ccc8f61abb4c2e3d3288860fe9be2ea
https://doi.org/10.1158/1538-7445.am2022-2840
https://doi.org/10.1158/1538-7445.am2022-2840
Publikováno v:
Translational Research. 196:62-70
Immune checkpoint blockade therapy (ICBT) has resulted in extended overall survival for some patients with certain types of cancer, most prominently including colorectal cancer (CRC) patients associated with microsatellite instability (MSI). However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458624cbd95ca97fb1e3cc5d81dd879d
https://doi.org/10.1016/j.trsl.2018.02.001
https://doi.org/10.1016/j.trsl.2018.02.001