Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Audray K Harris"'
Autor:
Dustin M McCraw, Mallory L Myers, Neetu M Gulati, Madhu Prabhakaran, Joshua Brand, Sarah Andrews, John R Gallagher, Samantha Maldonado-Puga, Alexander J Kim, Udana Torian, Hubza Syeda, Seyhan Boyoglu-Barnum, Masaru Kanekiyo, Adrian B McDermott, Audray K Harris
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011514 (2023)
Despite the availability of seasonal vaccines and antiviral medications, influenza virus continues to be a major health concern and pandemic threat due to the continually changing antigenic regions of the major surface glycoprotein, hemagglutinin (HA
Externí odkaz:
https://doaj.org/article/82d3481038c84757a30ef4e14fbf435c
Autor:
Mallory L. Myers, John R. Gallagher, De’Marcus D. Woolfork, Regan K. Stradtmann-Carvalho, Samantha Maldonado-Puga, Kevin W. Bock, Seyhan Boyoglu-Barnum, Hubza Syeda, Adrian Creanga, Derron A. Alves, Masaru Kanekiyo, Audray K. Harris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As new vaccine technologies and platforms, such as nanoparticles and novel adjuvants, are developed to aid in the establishment of a universal influenza vaccine, studying traditional influenza split/subunit vaccines should not be overlooked. Commerci
Externí odkaz:
https://doaj.org/article/12a8ae4464884095aa89e2048a346218
Autor:
Mallory L. Myers, John R. Gallagher, Alexander J. Kim, Walker H. Payne, Samantha Maldonado-Puga, Haralabos Assimakopoulos, Kevin W. Bock, Udana Torian, Ian N. Moore, Audray K. Harris
Publikováno v:
Nature Communications. 14
Influenza virus infects millions of people annually and can cause global pandemics. Hemagglutinin (HA) is the primary component of commercial influenza vaccines (CIV), and antibody titer to HA is a primary correlate of protection. Continual antigenic
Autor:
Mallory L. Myers, John R. Gallagher, Alexander J. Kim, Walker H. Payne, Kevin W. Bock, Udana Torian, Ian N. Moore, Audray K. Harris
Influenza virus infects millions of people annually and can cause global pandemics. Hemagglutinin (HA) is the primary component of commercial influenza vaccines (CIV), and antibody to HA is a primary correlate of protection. Persistent antigenic vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f9f4709a995fa8210ba14834066ae3
https://doi.org/10.1101/2022.09.22.509041
https://doi.org/10.1101/2022.09.22.509041
Autor:
John R. Gallagher, Dustin M. McCraw, Udana Torian, Neetu M. Gulati, Mallory L. Myers, Michael T. Conlon, Audray K. Harris
Publikováno v:
Vaccines, Vol 6, Iss 2, p 31 (2018)
Influenza viruses affect millions of people worldwide on an annual basis. Although vaccines are available, influenza still causes significant human mortality and morbidity. Vaccines target the major influenza surface glycoprotein hemagglutinin (HA).
Externí odkaz:
https://doaj.org/article/b2da208d3d264c15b8467b66aa2365de
Autor:
Syed M. Moin, Jeffrey C. Boyington, Seyhan Boyoglu-Barnum, Rebecca A. Gillespie, Gabriele Cerutti, Crystal Sao-Fong Cheung, Alberto Cagigi, John R. Gallagher, Joshua Brand, Madhu Prabhakaran, Yaroslav Tsybovsky, Tyler Stephens, Brian E. Fisher, Adrian Creanga, Sila Ataca, Reda Rawi, Kizzmekia S. Corbett, Michelle C. Crank, Gunilla B. Karlsson Hedestam, Jason Gorman, Adrian B. McDermott, Audray K. Harris, Tongqing Zhou, Peter D. Kwong, Lawrence Shapiro, John R. Mascola, Barney S. Graham, Masaru Kanekiyo
Publikováno v:
Immunity. 55:2405-2418.e7
Current influenza vaccines predominantly induce immunity to the hypervariable hemagglutinin (HA) head, requiring frequent vaccine reformulation. Conversely, the immunosubdominant yet conserved HA stem harbors a supersite that is targeted by broadly n
Publikováno v:
Microscopy and Microanalysis. 26:1308-1310
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses
Autor:
Rebecca A. Gillespie, Peter D. Kwong, Julie E. Ledgerwood, John R. Gallagher, Richard A. Koup, Madhu Prabhakaran, Brian E. Fisher, David R. Ambrozak, John R. Mascola, Ulrich Baxa, Masaru Kanekiyo, Barney S. Graham, Wing-Pui Kong, M. Gordon Joyce, Kathryn L Zephir, Adrian B. McDermott, Sarah F. Andrews, Hanne Andersen, Adrian Creanga, Adam K. Wheatley, Audray K. Harris, Kwanyee Leung, Ivelin S. Georgiev, Eun Sung Yang, Seyhan Boyoglu-Barnum, Yaroslav Tsybovsky, Hadi M. Yassine
Publikováno v:
Nature immunology
The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy. This necessitates new approaches that provide broader protection against
Autor:
Audray K. Harris, John R. Gallagher
Publikováno v:
The Journal of biological chemistry. 295(1)
African swine fever virus (ASFV) is a complex nucleocytoplasmic large DNA virus (NCLDV) that causes a devastating swine disease currently present in many countries of Africa, Europe, and Asia. Despite intense research efforts, relevant gaps in the ar
Autor:
Neetu M. Gulati, Audray K. Harris, Mallory L. Myers, Udana Torian, Michael T. Conlon, John R. Gallagher, Dustin M. McCraw
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
Influenza virus continues to be a major health problem due to the continually changing immunodominant head regions of the major surface glycoprotein, hemagglutinin (HA). However, some emerging vaccine platforms designed by biotechnology efforts, such