Zobrazeno 1 - 10
of 603
pro vyhledávání: '"Audrain, P."'
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD
Autor:
Elodie Chevalier, Mickael Audrain, Monisha Ratnam, Romain Ollier, Aline Fuchs, Kasia Piorkowska, Andrea Pfeifer, Marie Kosco-Vilbois, Tamara Seredenina, Tariq Afroz
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Abnormal cytoplasmic localization and accumulation of pathological transactive response DNA binding protein of 43 kDa (TDP-43) underlies several devastating diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degene
Externí odkaz:
https://doaj.org/article/eb7a4f8889a94b1f9b377bfd2cada429
Autor:
Thomas Gargot, Amandine Vachaud, Clémence Gilard, Alexia Audrain, Marie Gomot, Marco Guidotti, Frédéric Briend, Joëlle Malvy, Frédérique Bonnet Brilhault
Publikováno v:
JMIR Human Factors, Vol 11, p e55754 (2024)
BackgroundDeep pressure therapy (DPT) is widely used to reduce anxiety in children with autism spectrum disorder (ASD), but evidence of its efficacy is limited. ObjectiveThis study aims to design a usable, nonstigmatizing compressive armchair that c
Externí odkaz:
https://doaj.org/article/f4c35bbde57042d597c5fd406266fc2a
Autor:
Peter P. Reese, Salima Shah, Emily Funsten, Sandra Amaral, Janet Audrain-McGovern, Kristen Koepsell, Hunter Wessells, Jonathan D. Harper, Rebecca McCune, Charles D. Scales, Ziya Kirkali, Naim M. Maalouf, H. Henry Lai, Alana C. Desai, Hussein R. Al-Khalidi, Gregory E. Tasian
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Structured Problem Solving (SPS) is a patient-centered approach to promoting behavior change that relies on productive collaboration between coaches and participants and reinforces participant autonomy. We aimed to describe the de
Externí odkaz:
https://doaj.org/article/a4b4deee3e1d4641ae0c0263b5a8e5a5
Autor:
Allen L. Pan, Mickael Audrain, Emmy Sakakibara, Rajeev Joshi, Xiaodong Zhu, Qian Wang, Minghui Wang, Noam D. Beckmann, Eric E. Schadt, Sam Gandy, Bin Zhang, Michelle E. Ehrlich, Stephen R. Salton
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionDual specificity protein phosphatase 6 (DUSP6) was recently identified as a key hub gene in a causal VGF gene network that regulates late-onset Alzheimer’s disease (AD). Importantly, decreased DUSP6 levels are correlated with an increas
Externí odkaz:
https://doaj.org/article/66424ab08fc74d3ebe9d7d031f32fecc
Publikováno v:
Drug and Alcohol Dependence Reports, Vol 11, Iss , Pp 100234- (2024)
Background: Young adults 18–24 years old have the highest prevalence of cigarillo use, exposing young adults to comparable or higher nicotine levels and many of the same toxicants as combustible cigarettes. Identifying individual and product charac
Externí odkaz:
https://doaj.org/article/ba98e91d73ca434f9f5c3e74c0abfd19
Autor:
Rebecca J. Stevick, Bianca Audrain, Sébastien Bedu, Nicolas Dray, Jean-Marc Ghigo, David Pérez-Pascual
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Background Perturbations of animal-associated microbiomes from chemical stress can affect host physiology and health. While dysbiosis induced by antibiotic treatments and disease is well known, chemical, nonantibiotic drugs have recently bee
Externí odkaz:
https://doaj.org/article/2ae5d990e6034411a1ef50f0be5e7a3a
Autor:
Kyrie P. Grasekamp, Basile Beaud Benyahia, Najwa Taib, Bianca Audrain, Benjamin Bardiaux, Yannick Rossez, Nadia Izadi-Pruneyre, Maylis Lejeune, Xavier Trivelli, Zina Chouit, Yann Guerardel, Jean-Marc Ghigo, Simonetta Gribaldo, Christophe Beloin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract E. coli and most other diderm bacteria (those with two membranes) have an inner membrane enriched in glycerophospholipids (GPLs) and an asymmetric outer membrane (OM) containing GPLs in its inner leaflet and primarily lipopolysaccharides in
Externí odkaz:
https://doaj.org/article/b9942281d51d4ac09338188f3910d54c
Autor:
Matthew D. Stone, Melissa Mercincavage, E. Paul Wileyto, Andy S.L. Tan, Janet Audrain-McGovern, Andrea C. Villanti, Andrew A. Strasser
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Objective Plain packaging and graphic warning labels are two regulatory strategies that may impact cigarette risk beliefs and reduce consumption, but data are needed to better understand how smokers respond to such regulations. Methods Adult
Externí odkaz:
https://doaj.org/article/19a408be97734c70a28e270efad4b81a
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e48182 (2024)
BackgroundIn chronic mental illness, noncompliance with treatment significantly worsens the illness course and outcomes for patients. Considering that nearly 1 billion people worldwide experience mental health issues, including 1 of 5 Canadians in an
Externí odkaz:
https://doaj.org/article/912d026e09394bce8a816e6cc9621417
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