Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Audra F. Bryan"'
Autor:
Miles R. Bryan III, Xu Tian, Jui-Heng Tseng, Baggio A. Evangelista, Joey V. Ragusa, Audra F. Bryan, Winifred Trotman, David Irwin, Todd J. Cohen
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Tauopathies, including Alzheimer’s disease (AD), are a class of neurodegenerative diseases characterized by the presence of insoluble tau inclusions. Tau phosphorylation has traditionally been viewed as the dominant post-translational modi
Externí odkaz:
https://doaj.org/article/a224761b89a941c684570125212d6515
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-20 (2022)
Abstract Background Cohesin is an important structural regulator of the genome, regulating both three-dimensional genome organization and gene expression. The core cohesin trimer interacts with various HEAT repeat accessory subunits, yielding cohesin
Externí odkaz:
https://doaj.org/article/e29d9d38906e425f9f01183480dc16c9
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background The cohesin complex is essential for proper chromosome structure and gene expression. Defects in cohesin subunits and regulators cause changes in cohesin complex dynamics and thereby alter three-dimensional genome organization. Ho
Externí odkaz:
https://doaj.org/article/a35eeecd837c4d9cbac7861d46e725af
Autor:
Stephen W. Fesik, Dai H. Chung, William P. Tansey, David K. Flaherty, Alissa D. Guarnaccia, Eric J. Rellinger, April M. Weissmiller, Shelly L. Lorey, Brittany K. Matlock, Erin R. Aho, Chase M Woodley, Gregory C. Howard, Qi Liu, Audra F Bryan, Jing Wang
Publikováno v:
Nucleic Acids Research
WDR5 is a highly-conserved nuclear protein that performs multiple scaffolding functions in the context of chromatin. WDR5 is also a promising target for pharmacological inhibition in cancer, with small molecule inhibitors of an arginine-binding pocke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e98e8c1595ddbc0d9942a951da6351
https://doi.org/10.1093/nar/gkaa051
https://doi.org/10.1093/nar/gkaa051
Autor:
Alexandra F. Williams, Kyle Gregory, Prince J. Kannankeril, Feng Li, Cole Bozeman, Tarek S. Absi, Audra F Bryan, Yan Ru Su, Kelsey Tomasek, Carlos A. Fulmer
Publikováno v:
Heart Rhythm
Sudden unexpected infant death (SUID) occurs unpredictably and remains unexplained after scene investigation and autopsy. Approximately 1 in 7 cases of SUID can be related to a cardiac cause, and developmental regulation of cardiac ion channel genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c49d03fe023d3c482e3016d37dfa36
https://europepmc.org/articles/PMC8977237/
https://europepmc.org/articles/PMC8977237/
Publikováno v:
BMC genomics. 23(1)
Background The cohesin complex is essential for proper chromosome structure and gene expression. Defects in cohesin subunits and regulators cause changes in cohesin complex dynamics and thereby alter three-dimensional genome organization. However, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0214642f8c81f64f0dc186d56a08f23
https://pubmed.ncbi.nlm.nih.gov/35501690
https://pubmed.ncbi.nlm.nih.gov/35501690
Autor:
Feng Li, Prince J. Kannankeril, Carlos Fulmer, Yan Ru Su, Kelsey Tomasek, Cole Bozeman, Alexandra F. Williams, Kyle Gregory, Audra F Bryan
Publikováno v:
Circulation Research. 127
Sodium Voltage-Gated Channel Alpha Subunit 5 (SNC5A) plays a vital role in cardiac depolarization and has been implicated in Long QT Syndrome and sudden cardiac death. SCN5A encodes fetal and adult isoforms, differing by splicing of exon 6A or 6B, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5747cae64389fa602072816b723fbc0f
https://doi.org/10.1161/res.127.suppl_1.346
https://doi.org/10.1161/res.127.suppl_1.346