Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment

Autor: Antimycobacterial Susceptibility Testing Group, Georghiou, Sophia B., Rodwell, Timothy C., Korobitsyn, Alexei, Abbadi, Said H., Ajbani, Kanchan, Alffenaar, Jan-Willem, Alland, David, Alvarez, Nataly, Andres, Sönke, Ardizzoni, Elisa, Aubry, Alexandra, Baldan, Rossella, Ballif, Marie, Barilar, Ivan, Böttger, Erik C., Chakravorty, Soumitesh, Claxton, Pauline M., Cirillo, Daniela M., Comas, Iñaki, Coulter, Chris, Denkinger, Claudia M., Derendinger, Brigitta, Desmond, Edward P., Steenwinkel, Jurriaan E. M. de, Dheda, Keertan, Diacon, Andreas H., Dolinger, David L., Dooley, Kelly E., Egger, Matthias, Ehsani, Soudeh, Farhat, Maha R., Fattorini, Lanfranco, Finci, Iris, Fournier Le Ray, Laure, Furió, Victoria, Groenheit, Ramona, Gumbo, Tawanda, Heysell, Scott K., Hillemann, Doris, Hoffmann, Harald, Hsueh, Po-Ren, Hu, Yi, Huang, Hairong, Hussain, Alamdar, Ismail, Farzana, Izumi, Kiyohiko, Jagielski, Tomasz, Johnson, John L., Kambli, Priti, Kaniga, Koné, Karunaratne, G. H. R. Eranga, Sharma, Meenu Kaushal, Keller, Peter M., Kelly, Ellis C., Kholina, Margarita, Kohli, Mikashmi, Kranzer, Katharina, Laurenson, Ian F., Limberis, Jason, Lin, S-Y. Grace, Liu, Yongge, López-Gavín, Alexandre, Lyander, Anna, Machado, Diana, Martínez, Elena, Masood, Faisal, Mitarai, Satoshi, Mvelase, Nomonde R., Niemann, Stefan, Nikolayevskyy, Vladyslav, Maurer, Florian P., Merker, Matthias, Miotto, Paolo, Omar, Shaheed V., Otto-Knapp, Ralf, Palaci, Moisés, Palacios Gutiérrez, Juan José, Peacock, Sharon J., Peloquin, Charles A., Perera, Jennifer, Pierre-Audigier, Catherine, Pholwat, Suporn, Posey, James E., Prammananan, Therdsak, Rigouts, Leen, Robledo, Jaime, Rockwood, Neesha, Rodrigues, Camilla, Salfinger, Max, Schechter, Marcos C., Seifert, Marva, Sengstake, Sarah, Shinnick, Thomas, Shubladze, Natalia, Sintchenko, Vitali, Sirgel, Frederick, Somasundaram, Sulochana, Sterling, Timothy R., Spitaleri, Andrea, Streicher, Elizabeth, Supply, Philip, Svensson, Erik, Tagliani, Elisa, Tahseen, Sabira, Takaki, Akiko, Theron, Grant, Torrea, Gabriela, Van Deun, Armand, van Ingen, Jakko, Van Rie, Annelies, van Soolingen, Dick, Vargas Jr, Roger, Venter, Amour, Veziris, Nicolas, Villellas, Cristina, Viveiros, Miguel, Warren, Robin, Wen, Shu'an, Werngren, Jim, Wilkinson, Robert J., Yang, Caie, Yılmaz, F. Ferda, Zhang, Tingting, Zimenkov, Danila, Ismail, Nazir, Köser, Claudio U., Schön, Thomas

Publikováno v: European Respiratory Journal
European Respiratory Journal, 2022, 59 (4), pp.2200166. ⟨10.1183/13993003.00166-2022⟩
The European respiratory journal, vol 59, iss 4
European Respiratory Journal, 59, 4
Digital.CSIC. Repositorio Institucional del CSIC
instname
The European respiratory journal
European Respiratory Journal, 59

11 páginas, 2 figuras, 1 tabla
Inappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd6f200bc5d671097df27e2b044f06d
https://doi.org/10.1183/13993003.00166-2022

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Molecular detection of fluoroquinolone-resistance in multi-drug resistant tuberculosis in Cambodia suggests low association with XDR phenotypes

Autor: Murray Alan, Namouchi Amine, Cadet-Daniel Véronique, Pierre-Audigier Catherine, Heng Seiha, Surcouf Corinne, Gicquel Brigitte, Guillard Bertrand

Publikováno v: BMC Infectious Diseases, Vol 11, Iss 1, p 255 (2011)

Abstract Background Drug susceptibility testing (DST) remains an important concern for implementing treatment of MDR tuberculosis patients. Implementation of molecular tests for drug resistance identification would facilitate DST particularly in deve

Externí odkaz: https://doaj.org/article/27a2010963dc41959c30570b2db714c4

The use of GeneXpert remnants for drug resistance profiling and molecular epidemiology of tuberculosis in Libreville, Gabon

Autor: Alame-Emane, Amel Kévin, Pierre-Audigier, Catherine, Aboumegone-Biyogo, Oriane Cordelia, Nzoghe-Mveang, Amandine, Cadet-Daniel, Véronique, Sola, Christophe, Djoba-Siawaya, Joël Fleury, Gicquel, Brigitte, Takiff, Howard E.

Publikováno v: Journal of Clinical Microbiology
Journal of Clinical Microbiology, American Society for Microbiology, 2017, 55 (7), pp.2105-2115. ⟨10.1128/JCM.02257-16⟩
Journal of Clinical Microbiology, 2017, 55 (7), pp.2105-2115. ⟨10.1128/JCM.02257-16⟩

Multidrug-resistant (MDR) and extensively drug resistant (XDR) strains of Mycobacterium tuberculosis pose major problems for global health. The GeneXpert MTB/RIF (Xpert) assay rapidly detects resistance to rifampin (RIFr), but for detection of the ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b16a7ab5c28f5d6a93f90f7cd3ccc3c9
https://hal.archives-ouvertes.fr/hal-02185221

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