Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Aude-Claire Morillon"'
Autor:
Sofina Begum, Blair Z. Johnson, Aude-Claire Morillon, Rongchang Yang, Sze How Bong, Luke Whiley, Nicola Gray, Vanessa S. Fear, Leila Cuttle, Andrew J. A. Holland, Jeremy K. Nicholson, Fiona M. Wood, Mark W. Fear, Elaine Holmes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A growing body of evidence supports the concept of a systemic response to non-severe thermal trauma. This provokes an immunosuppressed state that predisposes paediatric patients to poor recovery and increased risk of secondary morbidity. In
Externí odkaz:
https://doaj.org/article/bd738ef484744b0d99df495bd98504fa
Autor:
Aude-Claire Morillon, Rachel D Williamson, Philip N Baker, Douglas B Kell, Louise C Kenny, Jane A English, Fergus P McCarthy, Cathal McCarthy
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230977 (2020)
IntroductionPre-eclampsia is a major cause of maternal and fetal mortality and morbidity worldwide. Its pathophysiology remains unclear, but mitochondrial dysfunction and oxidative stress have been implicated. L-Ergothioneine is a naturally occurring
Externí odkaz:
https://doaj.org/article/c7954483a34a4e88b21d08f42d240a65
Autor:
Debora Farias Batista Leite, Aude-Claire Morillon, Elias F Melo Júnior, Renato T Souza, Philip Baker, Ali Khashan
Publikováno v:
BMJ Open, Vol 9, Iss 8 (2019)
IntroductionTo date, there is no robust enough test to predict small-for-gestational-age (SGA) infants, who are at increased lifelong risk of morbidity and mortality.ObjectiveTo determine the accuracy of metabolomics in predicting SGA babies and eluc
Externí odkaz:
https://doaj.org/article/7d9c84ce8f9a491085c2bf9041f29c81
Autor:
Samuele Sala, Philipp Nitschke, Reika Masuda, Nicola Gray, Nathan Lawler, James M. Wood, Georgy Berezhnoy, Alejandro Bolaños, Berin A. Boughton, Caterina Lonati, Titus Rössler, Yogesh Singh, Ian D. Wilson, Samantha Lodge, Aude-Claire Morillon, Ruey Leng Loo, Drew Hall, Luke Whiley, Gary B. Evans, Tyler L. Grove, Steven C. Almo, Lawrence D. Harris, Elaine Holmes, Uta Merle, Christoph Trautwein, Jeremy K. Nicholson, Julien Wist
We present compelling evidence for the existence of an evolutionary adaptive response to viral agents such as SARS-CoV-2, that results in the humanin vivobiosynthesis of a family of compounds with potential antiviral activity. Using nuclear magnetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ddce5fd876c958f18b755968cee278
https://doi.org/10.1101/2023.05.08.23289637
https://doi.org/10.1101/2023.05.08.23289637
Autor:
Sven Pettersson, Ruey Leng Loo, Monique Ryan, Manfred Spraul, Sze-How Bong, Dale W. Edgar, Philipp Nitschke, Rongchang Yang, Sofina Begum, Samantha Lodge, Torben Kimhofer, Sung Tong Chin, Nathan G. Lawler, Toby Richards, Reika Masuda, Julien Wist, John C. Lindon, Luke Whiley, Drew Hall, Hartmut Schaefer, Berin A. Boughton, Aude-Claire Morillon, Bu B. Yeap, Elaine Holmes, Nicola Gray, Jeremy K. Nicholson
Publikováno v:
Journal of Proteome Research
We present a multivariate metabotyping approach to assess the functional recovery of nonhospitalized COVID-19 patients and the possible biochemical sequelae of "Post-Acute COVID-19 Syndrome", colloquially known as long-COVID. Blood samples were taken
Autor:
Sofina Begum, Blair Z. Johnson, Aude-Claire Morillon, Rongchang Yang, Sze How Bong, Luke Whiley, Nicola Gray, Vanessa S. Fear, Leila Cuttle, Andrew J. A. Holland, Jeremy K. Nicholson, Fiona M. Wood, Mark W. Fear, Elaine Holmes
Publikováno v:
Scientific reports. 12(1)
A growing body of evidence supports the concept of a systemic response to non-severe thermal trauma. This provokes an immunosuppressed state that predisposes paediatric patients to poor recovery and increased risk of secondary morbidity. In this stud
Autor:
Sven Pettersson, Monique Ryan, Nathan G. Lawler, Toby Richards, Edward Raby, Berin A. Boughton, Torben Kimhofer, Aude-Claire Morillon, Sze-How Bong, Dale W. Edgar, Rongchang Yang, Sofina Begum, Sung Tong Chin, Luke Whiley, Jerome D Coudert, Nicola Gray, Jeremy K. Nicholson, Elaine Holmes
Publikováno v:
Journal of Proteome Research
We performed quantitative metabolic phenotyping of blood plasma in parallel with cytokine/chemokine analysis from participants who were either SARS-CoV-2 (+) (n = 10) or SARS-CoV-2 (-) (n = 49). SARS-CoV-2 positivity was associated with a unique meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c0dd8c2cbc2564546160c7caa37523
http://hdl.handle.net/10044/1/91210
http://hdl.handle.net/10044/1/91210
Autor:
Jane A. English, Débora F. Leite, Shirish Yakkundi, Philip N. Baker, Louise C. Kenny, Aude-Claire Morillon, Lee A. Gethings, Grégoire Thomas, Fergus P. McCarthy
Publikováno v:
Metabolomics
Introduction Small for gestational age (SGA) may be associated with neonatal morbidity and mortality. Our understanding of the molecular pathways implicated is poor. Objectives Our aim was to determine the metabolic pathways involved in the pathophys
Autor:
Douglas B. Kell, Fergus P. McCarthy, Rachel D. Williamson, Aude-Claire Morillon, Louise C. Kenny, Philip N. Baker, Jane A. English, Cathal McCarthy
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230977 (2020)
Morillon, A C, Williamson, R D, Baker, P N, Kell, D B, Kenny, L C, English, J A, McCarthy, F P & McCarthy, C 2020, ' Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of preeclampsia ', PLOS ONE, vol. 15, no. 3, e0230977 . https://doi.org/10.1371/journal.pone.0230977
PLoS ONE
Morillon, A C, Williamson, R D, Baker, P N, Kell, D B, Kenny, L C, English, J A, McCarthy, F P & McCarthy, C 2020, ' Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of preeclampsia ', PLOS ONE, vol. 15, no. 3, e0230977 . https://doi.org/10.1371/journal.pone.0230977
PLoS ONE
IntroductionPre-eclampsia is a major cause of maternal and fetal mortality and morbidity worldwide. Its pathophysiology remains unclear, but mitochondrial dysfunction and oxidative stress have been implicated. L-Ergothioneine is a naturally occurring
Autor:
Philip N. Baker, Louise C. Kenny, Grégoire Thomas, James I. Langridge, Aude-Claire Morillon, Fergus P. McCarthy, Lee A. Gethings, Jane A. English, Shirish Yakkundi
Publikováno v:
Metabolomics
METABOLOMICS
METABOLOMICS
Introduction Preterm birth (PTB) is defined as birth occurring before 37 weeks’ gestation, affects 5–9% of all pregnancies in developed countries, and is the leading cause of perinatal mortality. Spontaneous preterm birth (sPTB) accounts for 31