Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Aude Bonehill"'
Autor:
Daphné Benteyn, Sébastien Anguille, Sandra Van Lint, Carlo Heirman, An MT Van Nuffel, Jurgen Corthals, Sebastian Ochsenreither, Wim Waelput, Katrien Van Beneden, Karine Breckpot, Viggo Van Tendeloo, Kris Thielemans, Aude Bonehill
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Tumor antigen–encoding mRNA for dendritic cell (DC)-based vaccination has gained increasing popularity in recent years. Within this context, two main strategies have entered the clinical trial stage: the use of mRNA for ex vivo antigen loading of D
Externí odkaz:
https://doaj.org/article/a462f9b35af243399c03aa019a2d528a
Autor:
Miwako Narita, Shunpei Iwaya, Yoshinori Nishizawa, Masuhiro Takahashi, Minami Iwabuchi, Takayoshi Uchiyama, Jun Takizawa, Aude Bonehill, Noriyuki Kasahara, Eri Oiwa, Shigeo Hashimoto
Publikováno v:
Molecular Medicine Reports
Molecular medicine reports, vol 12, iss 2
Molecular medicine reports, vol 12, iss 2
The aim of the present study was to enhance the efficiency of leukemia immunotherapy by increasing the antigen-specific cytotoxic T lymphocyte-inducing ability of leukemia cells. The leukemic plasmacytoid dendritic cell line PMDC05 containing the HLA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dd03cac435c9a0e9d08005fffe4f56
http://europepmc.org/articles/PMC4464268
http://europepmc.org/articles/PMC4464268
Autor:
An M. T. Van Nuffel, Kris Thielemans, Aude Bonehill, Jurgen Corthals, Carlo Heirman, Bart Neyns, Daphné Benteyn, Sofie Wilgenhof
Publikováno v:
Cancer Immunology, Immunotherapy. 64:381-388
PURPOSE: Melanoma patients with a high risk of recurrence may benefit from immunotherapy with mRNA-electroporated autologous monocyte-derived dendritic cells (DCs). Further benefit may be found in combining DC-therapy with interferon alfa-2b. PATIENT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef25c2e9a4040cd8d8b834d5cea86763
https://doi.org/10.1007/s00262-014-1642-8
https://doi.org/10.1007/s00262-014-1642-8
Autor:
Jurgen Corthals, Bart Neyns, Karine Breckpot, Sofie Wilgenhof, Kris Thielemans, Carlo Heirman, Aude Bonehill, Sandra Van Lint
Publikováno v:
Vrije Universiteit Brussel
Since decades, the main goal of tumor immunologists has been to increase the capacity of the immune system to mediate tumor regression. In this regard, one of the major focuses of cancer immunotherapy has been the design of vaccines promoting strong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd3bfaf4a62c52eaf573b802ceb6381
https://doi.org/10.1007/s00262-014-1558-3
https://doi.org/10.1007/s00262-014-1558-3
Autor:
Daphné Benteyn, Sofie Wilgenhof, K. Thielemans, A. M. T. Van Nuffel, Aude Bonehill, Bart Neyns, Carlo Heirman, Jurgen Corthals
Publikováno v:
ISBT Science Series. 8:161-164
Dendritic cell therapy has been optimized a lot aiming to induce a strong and broad immune response in terms of the recognized epitopes by both CD8+ and CD4+ T cells and the use of the patients' complete unique set of HLA molecules. We here give an o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f27d4ab11cedd5833facbc135a564f88
https://doi.org/10.1111/voxs.12035
https://doi.org/10.1111/voxs.12035
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1428
Dendritic cells (DCs) are the orchestrators of the immune system and are frequently used in clinical trials in order to boost the immune system in cancer patients. Among several available techniques for DC modification, mRNA electroporation is an int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47be8d99067f9ebac26d4888412493fc
https://pubmed.ncbi.nlm.nih.gov/27236795
https://pubmed.ncbi.nlm.nih.gov/27236795
Publikováno v:
Methods in Molecular Biology ISBN: 9781493936236
Dendritic cells (DCs) are the orchestrators of the immune system and are frequently used in clinical trials in order to boost the immune system in cancer patients. Among several available techniques for DC modification, mRNA electroporation is an int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b81b7bb6cfa7aaa94ec86bb78eb3b45
https://hdl.handle.net/20.500.14017/b68bc4f8-365f-414b-bfc8-4f52eb6dc650
https://hdl.handle.net/20.500.14017/b68bc4f8-365f-414b-bfc8-4f52eb6dc650
Autor:
Ralf M. Leonhardt, Peter Cresswell, Nathalie Demotte, Benoît Van den Eynde, Vincent Stroobant, Alexandre Michaux, Aude Bonehill, Arend Mulder, Wenbin Ma, Rosalie M. Luiten, Nathalie Vigneron, Pierre van der Bruggen
Publikováno v:
European Journal of Immunology. 42:1417-1428
Antitumor cytolytic T lymphocytes (CTLs) recognize peptides derived from cellular proteins and presented on MHC class I. One category of peptides recognized by these CTLs is derived from proteins encoded by "cancer-germline" genes, which are specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d336d1a5148e6cbca4411326f274f63b
https://doi.org/10.1002/eji.201141954
https://doi.org/10.1002/eji.201141954
Publikováno v:
Molecular Therapy. 19(5):841-853
Cancer immunotherapy aims to establish immune-mediated control of tumor growth by priming T-cell responses to target tumor-associated antigens. Three signals are required for T-cell activation: (i) presentation of cognate antigen in self MHC molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1488a38b7d1b587e1219c96dfe30fa31
Autor:
Arlette De Coninck, Carlo Heirman, Annieta Goossens, An M. T. Van Nuffel, L. Pierret, Jurgen Corthals, Nicolas van Baren, G Verfaillie, Diane Roseeuw, Bart Neyns, Ellen Degreef, Kris Thielemans, Truus Roelandt, Aude Bonehill, Ivan Van Riet
Publikováno v:
Vrije Universiteit Brussel
Melanoma metastases are characterized by pronounced neo-angiogenesis and spontaneous bleeding frequently occurring within central nervous system metastases. Clinically apparent spontaneous hemorrhage within subcutaneous melanoma metastases, however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5c99ef4e91c08f6ca001f28a2c9d85
https://doi.org/10.1097/cmr.0b013e32832eabb5
https://doi.org/10.1097/cmr.0b013e32832eabb5