Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Aude, Ratier"'
1
Akademický článek
Estimating the dynamic early life exposure to PFOA and PFOS of the HELIX children: Emerging profiles via prenatal exposure, breastfeeding, and diet
Autor: Aude Ratier, Maribel Casas, Regina Grazuleviciene, Remy Slama, Line Småstuen Haug, Cathrine Thomsen, Marina Vafeiadi, John Wright, Florence A. Zeman, Martine Vrijheid, Céline Brochot
Publikováno v: Environment International, Vol 186, Iss , Pp 108621- (2024)
In utero and children’s exposure to per- and polyfluoroalkyl substances (PFAS) is a major concern in health risk assessment as early life exposures are suspected to induce adverse health effects. Our work aims to estimate children’s exposure (fro
Externí odkaz: https://doaj.org/article/3ab6f033a11d477c99d126fa86f7f776
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2
Akademický článek
Accumulation-depuration data collection in support of toxicokinetic modelling
Autor: Aude Ratier, Sandrine Charles
Publikováno v: Scientific Data, Vol 9, Iss 1, Pp 1-7 (2022)
Measurement(s) chemical concentration Technology Type(s) High-performance Liquid Chromatography-UV • radioactivity detection • high resolution mass spectrometry Sample Characteristic - Organism Gammarus pulex Sample Characteristic - Environment p
Externí odkaz: https://doaj.org/article/2a1b9137cba846a9911362c8d912221a
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3
Akademický článek
rbioacc: An R-package to analyze toxicokinetic data
Autor: Aude Ratier, Virgile Baudrot, Miléna Kaag, Aurélie Siberchicot, Christelle Lopes, Sandrine Charles
Publikováno v: Ecotoxicology and Environmental Safety, Vol 242, Iss , Pp 113875- (2022)
The R-package rbioacc allows to analyse experimental data from bioaccumulation tests where organisms are exposed to a chemical (exposure) then put into clean media (depuration). Internal concentrations are measured over time during the experiment. rb
Externí odkaz: https://doaj.org/article/035050a4056d4426b73d06187612b4a8
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4
Improvements in Estimating Bioaccumulation Metrics in the Light of Toxicokinetic Models and Bayesian Inference
Autor: Sandrine CHARLES, Christelle LOPES, Aude RATIER
Publikováno v: Archives of Environmental Contamination and Toxicology
Archives of Environmental Contamination and Toxicology, 2022, 83 (4), pp.339-348. ⟨10.1007/s00244-022-00947-2⟩
The surveillance of chemical substances in the scope of Environmental Risk Assessment (ERA) is classically performed through bio-assays from which data are collected and then analysed and/or modelled. Some analysis are based on the fitting of toxicok
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c06b08196838c75408ef2c6a8a93314
https://doi.org/10.1007/s00244-022-00947-2
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5
New perspectives on the calculation of bioaccumulation metrics for active substances in living organisms
Autor: Christelle Lopes, Sandrine Charles, Patrice Carpentier, Vanessa Mazerolles, Aude Ratier, Gauthier Multari
Publikováno v: Integrated Environmental Assessment and Management
Integrated Environmental Assessment and Management, 2022, 18 (1), pp.10-18. ⟨10.1002/ieam.4439⟩
Integrated Environmental Assessment and Management, Wiley, 2021, ⟨10.1002/ieam.4439⟩
Today, only few ready-to-use and convenient decision-making tools are available in ecotoxicology concerning accumulation and effects of chemical substances on organisms, accounting for exposure situations that are known to be complex (routes of expos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef225b5f3991cc0fbb97c32cde749934
https://doi.org/10.1002/ieam.4439
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6
In Silico Methods for Environmental Risk Assessment: Principles, Tiered Approaches, Applications, and Future Perspectives
Autor: Maria Chiara, Astuto, Matteo R, Di Nicola, José V, Tarazona, A, Rortais, Yann, Devos, A K Djien, Liem, George E N, Kass, Maria, Bastaki, Reinhilde, Schoonjans, Angelo, Maggiore, Sandrine, Charles, Aude, Ratier, Christelle, Lopes, Ophelia, Gestin, Tobin, Robinson, Antony, Williams, Nynke, Kramer, Edoardo, Carnesecchi, Jean-Lou C M, Dorne
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2425
This chapter aims to introduce the reader to the basic principles of environmental risk assessment of chemicals and highlights the usefulness of tiered approaches within weight of evidence approaches in relation to problem formulation i.e., data avai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41fa99114e0e4bd8223609000861a5e0
https://pubmed.ncbi.nlm.nih.gov/35188648
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8
Taking full advantage of modelling to better assess environmental risk due to xenobiotics
Autor: Baudrot, Gauthier Multari, Wu D, Christelle Lopes, Sandrine Charles, Aurélie Siberchicot, Aude Ratier
Publikováno v: Environmental Science and Pollution Research
Environmental Science and Pollution Research, In press, ⟨10.1007/s11356-021-15042-7⟩
Environmental Science and Pollution Research, Springer Verlag, In press, ⟨10.1007/s11356-021-15042-7⟩
In the European Union, more than 100,000 man-made chemical substances are awaiting an environmental risk assessment (ERA). Simultaneously, ERA of chemicals has now entered a new era. Indeed, recent recommendations from regulatory bodies underline a c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfc809410613bd6ecb0f047f08cccad
https://hal.science/hal-03362566/document
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9
Generic Solving of One-compartment Toxicokinetic Models
Autor: Christelle Lopes, Sandrine Charles, Aude Ratier
Publikováno v: Journal of Exploratory Research in Pharmacology
Journal of Exploratory Research in Pharmacology, 2021, ⟨10.14218/JERP.2021.00024⟩
Journal of Exploratory Research in Pharmacology, Xia & He Publishing, 2021, ⟨10.14218/JERP.2021.00024⟩
This paper gives the full analytical solution of the generic set of ordinary differential equations that define one-compartment toxicokinetic models. These models describe uptake and elimination processes taking place within living organisms when exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca483c4d7e4174539c2883738344f63
https://hal.science/hal-03362341/document
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10
rbioacc: An R-package to analyze toxicokinetic data
Autor: Aurélie Siberchicot, Miléna Kaag, Christelle Lopes, Sandrine Charles, Virgile Baudrot, Aude Ratier
Publikováno v: Ecotoxicology and Environmental Safety
Ecotoxicology and Environmental Safety, 2022, 242, pp.113875. ⟨10.1016/j.ecoenv.2022.113875⟩
Summary The R package rbioacc is dedicated to the analysis of experimental data collected from bioaccumulation tests. It provides ready-to-use functions to visualise a data set and to estimate bioaccumulation metrics to be further used in support of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca048fda4ef1c6bef5949ef9d646f230
https://doi.org/10.1016/j.ecoenv.2022.113875
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