MKS-NPHP module proteins control ciliary shedding at the transition zone.

Autor: Delphine Gogendeau, Michel Lemullois, Pierrick Le Borgne, Manon Castelli, Anne Aubusson-Fleury, Olivier Arnaiz, Jean Cohen, Christine Vesque, Sylvie Schneider-Maunoury, Khaled Bouhouche, France Koll, Anne-Marie Tassin

Publikováno v: PLoS Biology, Vol 18, Iss 3, p e3000640 (2020)

Ciliary shedding occurs from unicellular organisms to metazoans. Although required during the cell cycle and during neurogenesis, the process remains poorly understood. In all cellular models, this phenomenon occurs distal to the transition zone (TZ)

Externí odkaz: https://doaj.org/article/111959731b764aa29041317dbaa14256

Sequence and Properties of Cagein, a Coiled‐Coil Scaffold Protein Linking Basal Bodies in the Polykinetids of the Ciliate Euplotes aediculatus

Autor: Deben Banerjee, Maurice D Butler, John A. Kloetzel, Anne Aubusson-Fleury, Matteo Mozzicafreddo

Publikováno v: Journal of Eukaryotic Microbiology. 68

In the hypotrich ciliate Euplotes, many individual basal bodies are grouped together in tightly packed clusters, forming ventral polykinetids. These groups of basal bodies (which produce compound ciliary organelles such as cirri and oral membranelles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8c07818d085d34001f5dbb1d0aa23b
https://doi.org/10.1111/jeu.12850

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Mutations in Outer Dynein Arm Heavy Chain DNAH9 Cause Motile Cilia Defects and Situs Inversus

Autor: Siobhán B. Carr, Anne Aubusson-Fleury, Mellisa Dixon, Amelia Shoemark, Thomas Burgoyne, Jean-François Papon, Lucy Jenkins, Lucie Thomas, Claire Hogg, Robert A. Hirst, Estelle Escudier, Farheen Daudvohra, Hannah M. Mitchison, Bruno Louis, Andrew G. Nicholson, Mitali P. Patel, Pierrick le Borgne, Serge Amselem, Paul Aurora, Thomas Cullup, Michel Lemullois, Anne-Marie Tassin, Marie Legendre, Joseph Hayes, Mahmoud R. Fassad, Christopher O'Callaghan

Publikováno v: American Journal of Human Genetics
American Journal of Human Genetics, 2018, 103 (6), pp.984--994. ⟨10.1016/j.ajhg.2018.10.016⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2018, 103 (6), pp.984--994. ⟨10.1016/j.ajhg.2018.10.016⟩

International audience; Motile cilia move body fluids and gametes and the beating of cilia lining the airway epithelial surfaces ensures that they are kept clear and protected from inhaled pathogens and consequent respiratory infections. Dynein motor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa4277af9cbe1ee0855a58d345d0e1f
https://hal.science/hal-02178023

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