Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aubrey K. Hubbard"'
Autor:
Derek W. Brown, Liam D. Cato, Yajie Zhao, Satish K. Nandakumar, Erik L. Bao, Eugene J. Gardner, Aubrey K. Hubbard, Alexander DePaulis, Thomas Rehling, Lei Song, Kai Yu, Stephen J. Chanock, John R. B. Perry, Vijay G. Sankaran, Mitchell J. Machiela
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Clonal hematopoiesis (CH)—age-related expansion of mutated hematopoietic clones—can differ in frequency and cellular fitness by CH type (e.g., mutations in driver genes (CHIP), gains/losses and copy-neutral loss of chromosomal segments (
Externí odkaz:
https://doaj.org/article/77165817170e4e85a1c42338d2c3eefb
Autor:
Tianzhong Yang, Lauren J. Mills, Aubrey K. Hubbard, Rui Cao, Andrew Raduski, Mitchell J. Machiela, Logan G. Spector
Publikováno v:
HGG Advances, Vol 5, Iss 1, Pp 100254- (2024)
Summary: Knowledge of Ewing sarcoma (EWS) risk factors is exceedingly limited; however, multiple small, independent studies have suggested a possible connection between hernia and EWS. By leveraging hernia summary statistics from the UK Biobank and a
Externí odkaz:
https://doaj.org/article/4174c41eac61493c9d85b5d97c8878a5
Autor:
Mitchell J. Machiela, Wen-Yi Huang, Wendy Wong, Sonja I. Berndt, Joshua Sampson, Jonas De Almeida, Mustapha Abubakar, Jada Hislop, Kai-Ling Chen, Casey Dagnall, Norma Diaz-Mayoral, Mary Ferrell, Michael Furr, Alex Gonzalez, Belynda Hicks, Aubrey K. Hubbard, Amy Hutchinson, Kevin Jiang, Kristine Jones, Jia Liu, Erikka Loftfield, Jennifer Loukissas, Jerome Mabie, Shannon Merkle, Eric Miller, Lori M. Minasian, Ellen Nordgren, Brian Park, Paul Pinsky, Thomas Riley, Lorena Sandoval, Neeraj Saxena, Aurelie Vogt, Jiahui Wang, Craig Williams, Patrick Wright, Meredith Yeager, Bin Zhu, Claire Zhu, Stephen J. Chanock, Montserrat Garcia-Closas, Neal D. Freedman
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial is a prospective cohort study of nearly 155,000 U.S. volunteers aged 55–74 at enrollment in 1993–2001. We developed the PLCO Atlas Project, a large resource for mul
Externí odkaz:
https://doaj.org/article/18e9cf5db56e4fb2a19dac1e5bed4a75
Autor:
Diana W. Lone, Karim T. Sadak, Bradley S. Miller, Jeannette M. Sample, Aubrey K. Hubbard, Caryn Wolter, Michelle Roesler, Michelle Nuno, Jenny N. Poynter
Publikováno v:
J Endocrinol Metab
BACKGROUND AND AIMS: Intracranial germ cell tumor (iGCT) survivors have multiple risk factors for growth hormone (GH) deficiency, a commonly reported late effect in childhood cancer survivors. The objective of this study is to examine the prevalence
Autor:
Brandon J. Diessner, Mitchell J. Machiela, Beau R. Webber, Logan G. Spector, Joshua D. Schiffman, Aubrey K. Hubbard
Publikováno v:
Int J Cancer
Ewing sarcoma (ES) is the second most common primary bone tumor in children and adolescents. There are few known epidemiological or genetic risk factors for ES. Numerous reports describe incidence rates and trends within the United States, but intern
Autor:
Karina Braga Ribeiro, Gabriela A Rojas, Brandon J. Diessner, Aubrey K. Hubbard, Logan G. Spector
Publikováno v:
Int J Cancer
Osteosarcoma (OS) is the most common primary bone tumor in children and adolescents. The etiology of OS is largely unknown but may be informed by comparisons of incidence and trends between geographic regions. Using the Cancer Incidence in Five Conti
Autor:
Jason Yat-Yang Wong, Batel Blechter, Aubrey K. Hubbard, Jianxin Shi, Wei Hu, Mohammad Rahman, Shahinaz Gadalla, Mitchell Machiela, Nathaniel Rothman, Qing Lan
Publikováno v:
Cancer Research. 83:3009-3009
Telomere length is a biomarker reflective of aging and genomic instability. We previously found associations between longer measured leukocyte telomere length (LTL) and increased lung cancer risk in a pooled nested case-control study with 847 cases.
Publikováno v:
Leukemia Research. 126:107022
Autor:
Aubrey K. Hubbard, Michaela Richardson, Michelle A. Rosesler, Adina Cioc, Erica D. Warlick, Jenny N. Poynter, Phuong L. Nguyen
Publikováno v:
Leuk Lymphoma
Myelodysplastic syndromes (MDS) are a heterogeneous group of blood disorders. Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with a chemopreventive effect in some cancers. We evaluated associations between NSAID use and MDS in a popula
Publikováno v:
Pediatric Blood & Cancer. 69
Although global differences in the incidence of neuroblastoma have been examined, the underlying mechanism has yet to be elucidated. Previous studies have suggested genetic ancestry and human development index (HDI) as contributing factors, but few s