Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aubrey C. Cantrell"'
Publikováno v:
Cells, Vol 12, Iss 10, p 1428 (2023)
Cardiac fibrosis plays an essential role in the development of diastolic dysfunction and contributes to heart failure with preserved ejection fraction (HFpEF). Our previous studies suggested Sirtuin 3 (SIRT3) as a potential target for cardiac fibrosi
Externí odkaz:
https://doaj.org/article/550926eac8ad4ba28486c308f12dc2b5
Publikováno v:
Cells, Vol 12, Iss 7, p 1060 (2023)
The induction of hypoxia tolerance has emerged as a novel therapeutic strategy for the treatment of ischemic diseases. The disruption of hypoxic signaling by hyperglycemia has been shown to contribute to diabetic cardiomyopathy. In this study, we exp
Externí odkaz:
https://doaj.org/article/d5abf02186db48c792f6027249ef7fa9
Publikováno v:
Physiological Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract Angiotensin II (Ang‐II) is one of the major contributors to the progression of renal fibrosis, inflammation, glomerular injury, and chronic kidney disease. Emerging evidence suggests that renal glycolysis plays an important role in renal f
Externí odkaz:
https://doaj.org/article/6eb662de8baf43abbbcaba403fb10c43
Publikováno v:
Cells, Vol 10, Iss 3, p 548 (2021)
Pericytes, as mural cells covering microvascular capillaries, play an essential role in vascular remodeling and maintaining vascular functions and blood flow. Pericytes are crucial participants in the physiological and pathological processes of cardi
Externí odkaz:
https://doaj.org/article/dcd7fa61434a45a7ad00e89c97142ca0
Autor:
Xiaochen He, Aubrey C Cantrell, Quinesha A Williams, Wei Gu, Yingjie Chen, Jian-Xiong Chen, Heng Zeng
Publikováno v:
bioRxiv
Coronary microvascular dysfunction (CMD) has been shown to contribute to cardiac hypertrophy and heart failure with preserved ejection fraction. At this point, there are no proven treatments for CMD. We have shown that histone acetylation may play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e7324f98adeb1297e5d78a373550f8
https://europepmc.org/articles/PMC9934706/
https://europepmc.org/articles/PMC9934706/
Publikováno v:
Hypertension. 79
Aims: Cardiomyocyte-specific knockout of Sirtuin 3 (SIRT3cKO) in mice results in heart failure which is, at least in part, attributable to activation of the ferroptotic cell death pathway. Using a ferroptosis inhibitor ferrostatin-1 (Fer-1), we teste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce2bd9e4c6f8c73ba228e18f1974965
https://doi.org/10.1161/hyp.79.suppl_1.p028
https://doi.org/10.1161/hyp.79.suppl_1.p028
Publikováno v:
Journal of cellular physiology. 237(8)
Hypertension is an important risk factor in the pathogenesis of diastolic dysfunction. Growing evidence indicates that glucose metabolism plays an essential role in diastolic dysfunction. TP53-induced glycolysis and apoptosis regulator (TIGAR) has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ab395e2646a899459b4377a9c90f9d
https://pubmed.ncbi.nlm.nih.gov/35621078
https://pubmed.ncbi.nlm.nih.gov/35621078
Publikováno v:
Journal of cellular physiologyREFERENCES. 236(11)
Endothelial glycolytic metabolism plays an important role in the process of angiogenesis. TP53-induced glycolysis and apoptosis regulator (TIGAR) is a significant mediator of cellular energy homeostasis. However, the role of TIGAR in endothelial meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72e4f2d59838b375fb71de16e93ec46
https://pubmed.ncbi.nlm.nih.gov/33928637
https://pubmed.ncbi.nlm.nih.gov/33928637
Publikováno v:
Cells, Vol 10, Iss 548, p 548 (2021)
Cells
Cells
Pericytes, as mural cells covering microvascular capillaries, play an essential role in vascular remodeling and maintaining vascular functions and blood flow. Pericytes are crucial participants in the physiological and pathological processes of cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a20ba02d176c7329e45fc3ad97c1221
https://www.mdpi.com/2073-4409/10/3/548
https://www.mdpi.com/2073-4409/10/3/548