Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aubrey C. Cantrell"'
Autor:
Xiaochen He, Quinesha A. Williams, Aubrey C. Cantrell, Jessie Besanson, Heng Zeng, Jian-Xiong Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2433 (2024)
Hypertension is the key contributor to pathological cardiac hypertrophy. Growing evidence indicates that glucose metabolism plays an essential role in cardiac hypertrophy. TP53-induced glycolysis and apoptosis regulator (TIGAR) has been shown to regu
Externí odkaz:
https://doaj.org/article/637f66e6f6834ff98bb15be04ff60b87
Publikováno v:
Cells, Vol 12, Iss 10, p 1428 (2023)
Cardiac fibrosis plays an essential role in the development of diastolic dysfunction and contributes to heart failure with preserved ejection fraction (HFpEF). Our previous studies suggested Sirtuin 3 (SIRT3) as a potential target for cardiac fibrosi
Externí odkaz:
https://doaj.org/article/550926eac8ad4ba28486c308f12dc2b5
Publikováno v:
Physiological Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract Angiotensin II (Ang‐II) is one of the major contributors to the progression of renal fibrosis, inflammation, glomerular injury, and chronic kidney disease. Emerging evidence suggests that renal glycolysis plays an important role in renal f
Externí odkaz:
https://doaj.org/article/6eb662de8baf43abbbcaba403fb10c43
Publikováno v:
Cells, Vol 12, Iss 7, p 1060 (2023)
The induction of hypoxia tolerance has emerged as a novel therapeutic strategy for the treatment of ischemic diseases. The disruption of hypoxic signaling by hyperglycemia has been shown to contribute to diabetic cardiomyopathy. In this study, we exp
Externí odkaz:
https://doaj.org/article/d5abf02186db48c792f6027249ef7fa9
Publikováno v:
Cells, Vol 10, Iss 3, p 548 (2021)
Pericytes, as mural cells covering microvascular capillaries, play an essential role in vascular remodeling and maintaining vascular functions and blood flow. Pericytes are crucial participants in the physiological and pathological processes of cardi
Externí odkaz:
https://doaj.org/article/dcd7fa61434a45a7ad00e89c97142ca0
Autor:
Xiaochen He, Aubrey C Cantrell, Quinesha A Williams, Wei Gu, Yingjie Chen, Jian-Xiong Chen, Heng Zeng
Publikováno v:
bioRxiv
Coronary microvascular dysfunction (CMD) has been shown to contribute to cardiac hypertrophy and heart failure with preserved ejection fraction. At this point, there are no proven treatments for CMD. We have shown that histone acetylation may play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e7324f98adeb1297e5d78a373550f8
https://europepmc.org/articles/PMC9934706/
https://europepmc.org/articles/PMC9934706/
Publikováno v:
Hypertension. 79
Aims: Cardiomyocyte-specific knockout of Sirtuin 3 (SIRT3cKO) in mice results in heart failure which is, at least in part, attributable to activation of the ferroptotic cell death pathway. Using a ferroptosis inhibitor ferrostatin-1 (Fer-1), we teste
Publikováno v:
Journal of cellular physiology. 237(8)
Hypertension is an important risk factor in the pathogenesis of diastolic dysfunction. Growing evidence indicates that glucose metabolism plays an essential role in diastolic dysfunction. TP53-induced glycolysis and apoptosis regulator (TIGAR) has be
Publikováno v:
Journal of cellular physiologyREFERENCES. 236(11)
Endothelial glycolytic metabolism plays an important role in the process of angiogenesis. TP53-induced glycolysis and apoptosis regulator (TIGAR) is a significant mediator of cellular energy homeostasis. However, the role of TIGAR in endothelial meta
Publikováno v:
Cells, Vol 10, Iss 548, p 548 (2021)
Cells
Cells
Pericytes, as mural cells covering microvascular capillaries, play an essential role in vascular remodeling and maintaining vascular functions and blood flow. Pericytes are crucial participants in the physiological and pathological processes of cardi