Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aubrey B. Gosnell"'
Autor:
Claude L. Holder, Paul H. Slitonen, William Slikker, Carolyn J. Branscomb, Walter A. Korfmacher, Harold C. Thompson, Carl E. Cerniglia, Aubrey B. Gosnell, Jackson O. Lay
Publikováno v:
Journal of analytical toxicology. 14(4)
Elimination and metabolic profiles of the glucuronide products of doxylamine and its N-demethylated metabolites were determined after the oral administration of (14C)-doxylamine succinate (13.3 and 133 mg/kg doses) to male and female Fischer 344 rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2751e27daf143bc1bddd666d3702cd54
https://pubmed.ncbi.nlm.nih.gov/1975634
https://pubmed.ncbi.nlm.nih.gov/1975634
Autor:
Aubrey B. Gosnell
Publikováno v:
Journal of Chemical Education. 67:A84
This is an excellent text for an introductory course in macromolecular science for the student who has a good understanding of organic and physical chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c1177b1d30199fcde0a89308e7a6df
https://doi.org/10.1021/ed067pa84.1
https://doi.org/10.1021/ed067pa84.1
Publikováno v:
Organic Mass Spectrometry. 20:435-439
The chemical ionization mass spectrometric (CIMS) analysis of doxylamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine, and related compounds, using both ammonia and methane as reagent gases, is discussed. The two reagent gases did not p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716a9627e4792e701b1a23f510e3fb0b
https://doi.org/10.1002/oms.1210200702
https://doi.org/10.1002/oms.1210200702
Autor:
Harold C. Thompson, Aubrey B. Gosnell, Kenneth L. Rowland, J L Cmarik, Paul H. Siitonen, Claude L. Holder
Publikováno v:
Journal of Analytical Toxicology. 11:252-256
Male and female Fisher 344 rats (12 per group) were dosed by gavage with either 2 or 10 mg (based on the free amine) pyrilamine maleate containing about 12 and 6 muCi 14C-pyrilamine maleate, respectively, to determine excretion of the activity as a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163cee97bd3abb65dca8ae420c7a1ec3
https://doi.org/10.1093/jat/11.6.252
https://doi.org/10.1093/jat/11.6.252
Publikováno v:
Journal of High Resolution Chromatography. 9:435-440
A high resolution gas chromatographic method is described for the separation of rhesus monkey urinary metabolites of doxylamine with the use of on-column injection, a fused silica column (DB-1701), and nitrogen/phosphorus detection. An ancillary sepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1fc85362d4ae9fbf272487dc25f92fb
https://doi.org/10.1002/jhrc.1240090804
https://doi.org/10.1002/jhrc.1240090804
Autor:
Walter A. Korfmacher, Claude L. Holder, Harold C. Thompson, William Slikker, Larry G. Rushing, Aubrey B. Gosnell
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 419:113-122
This study describes the use of gas chromatographic-mass spectrometric, high-performance liquid chromatographic and capillary column gas chromatographic separation techniques in demonstrating the production of several artifactual compounds reported i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6556b33d689f56e35e237f43160713fe
https://doi.org/10.1016/0378-4347(87)80271-2
https://doi.org/10.1016/0378-4347(87)80271-2
Publikováno v:
Archives of Environmental Contamination and Toxicology. 11:447-455
A simple bioassay procedure employingDaphnia orHyalella that can be conducted in the field is described as an alternative to chemical analysis to determine safe reentry into crops treated with pesticides. Dislodgeable residues on the foliage of peach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7329adf684b6c539fa5b4e1fed432edb
https://doi.org/10.1007/bf01056071
https://doi.org/10.1007/bf01056071
Autor:
Aubrey B. Gosnell, Dwight W. Miller, Walter A. Korfmacher, Claude L. Holder, Jackson O. Lay, Paul H. Siitonen
Publikováno v:
Biological Mass Spectrometry. 13:627-632
Three glucuronide metabolites of doxylamine succinate were collected in a single fraction using high-performance liquid chromatography (HPLC) from the urine of dosed male Fischer 344 rats. The metabolites were then separated using an additional HPLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031df7d0cfe1adbc3bc0d488d112f485
https://doi.org/10.1002/bms.1200131108
https://doi.org/10.1002/bms.1200131108
Autor:
Paul H. Siitonen, Joan L. Cmarik, Claude L. Holder, Aubrey B. Gosnell, Harold C. Thompson, Kenneth L. Rowland
Publikováno v:
Journal of analytical toxicology. 10(1)
Experiments were conducted with male and female rats (12 per group) dosed by gavage with 2 or 20 mg (based on the free amine) doxylamine succinate containing about 10 microCi 14C-doxylamine succinate to determine distribution and excretion of the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd5a3a0e5ae0b1c55164a40914798aa
https://pubmed.ncbi.nlm.nih.gov/3951203
https://pubmed.ncbi.nlm.nih.gov/3951203
Autor:
Aubrey B. Gosnell, William Slikker, Harold C. Thompson, Walter A. Korfmacher, Claude L. Holder
Publikováno v:
Biomedical mass spectrometry. 12(4)
This study describes the use of mass spectrometry (MS), high-performance liquid chromatography (HPLC) and chemical derivatization techniques for the identification of doxylamine and five rhesus monkey urinary metabolites. The analyses were performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb62a218c2febd9914710457c501a9b
https://pubmed.ncbi.nlm.nih.gov/2861861
https://pubmed.ncbi.nlm.nih.gov/2861861