Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Aubin, Moutal"'
Autor:
Lucas J. Handlin, Natalie L. Macchi, Nicolas L. A. Dumaire, Lyuba Salih, Erin N. Lessie, Kyle S. McCommis, Aubin Moutal, Gucan Dai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cell membranes consist of heterogeneous lipid nanodomains that influence key cellular processes. Using FRET-based fluorescent assays and fluorescence lifetime imaging microscopy (FLIM), we find that the dimension of cholesterol-enriched orde
Externí odkaz:
https://doaj.org/article/fad39d75223c4dd28e6df44fc3615e59
Autor:
Robson C. Lillo Vizin, Hisakatsu Ito, Caroline M. Kopruszinski, Megumi Ikegami, Daigo Ikegami, Xu Yue, Edita Navratilova, Aubin Moutal, Stephen L. Cowen, Frank Porreca
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Sleep disruption and negative affect are attendant features of many psychiatric and neurological conditions that are often co-morbid including major depressive disorder, generalized anxiety disorder and chronic pain. Whether there is a causa
Externí odkaz:
https://doaj.org/article/e9f2b7dbc8284f51a50b42ea8e576b55
Autor:
Chinnasamy Dhanalakshmi, Udaiyappan Janakiraman, Aubin Moutal, Kohji Fukunaga, Rajesh Khanna, Mark A. Nelson
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106620- (2024)
Externí odkaz:
https://doaj.org/article/019782f4aa7943a487410ee36aa7ba39
Autor:
Yue-Peng Jiang, Song Wang, Wei-Dong Lai, Xue-Qing Wu, Yan Jin, Zheng-Hao Xu, Aubin Moutal, Rajesh Khanna, Ki Duk Park, Zhi-Ming Shan, Cheng-Ping Wen, Jie Yu
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-17 (2022)
Abstract Background Rheumatoid arthritis patients usually suffer from arthritic chronic pain. However, due to an incomplete understanding of the mechanisms underlying autoimmune disorders, the management of arthritic pain is unsatisfactory. Here, we
Externí odkaz:
https://doaj.org/article/9f159bb881ee4f6ea9415d3b16a41318
Autor:
Xue-Qing Wu, Bei Tan, Yu Du, Lin Yang, Ting-Ting Hu, Yi-La Ding, Xiao-Yun Qiu, Aubin Moutal, Rajesh Khanna, Jie Yu, Zhong Chen
Publikováno v:
Neurobiology of Disease, Vol 183, Iss , Pp 106164- (2023)
Phototherapy is an emerging non-pharmacological treatment for depression, circadian rhythm disruptions, and neurodegeneration, as well as pain conditions including migraine and fibromyalgia. However, the mechanism of phototherapy-induced antinocicept
Externí odkaz:
https://doaj.org/article/b044bfcefcf34a06b0117ff1d1f4cda1
Autor:
Liberty François-Moutal, David Donald Scott, Andrew J. Ambrose, Christopher J. Zerio, Marina Rodriguez-Sanchez, Kumara Dissanayake, Danielle G. May, Jacob M. Carlson, Edward Barbieri, Aubin Moutal, Kyle J. Roux, James Shorter, Rajesh Khanna, Sami J. Barmada, Leeanne McGurk, May Khanna
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no cure or effective treatment in which TAR DNA Binding Protein of 43 kDa (TDP-43) abnormally accumulates into misfolded protein aggregates in affected neurons. It
Externí odkaz:
https://doaj.org/article/15ebfd3809d6429cb150916d1d91bb88
Autor:
Santiago I. Loya-López, Paz Duran, Dongzhi Ran, Aida Calderon-Rivera, Kimberly Gomez, Aubin Moutal, Rajesh Khanna
Publikováno v:
Neurobiology of Pain, Vol 12, Iss , Pp 100109- (2022)
The voltage-gated sodium NaV1.7 channel sets the threshold for electrogenesis. Mutations in the gene encoding human NaV1.7 (SCN9A) cause painful neuropathies or pain insensitivity. In dorsal root ganglion (DRG) neurons, activity and trafficking of Na
Externí odkaz:
https://doaj.org/article/a9a696a84f284dbf8f3cba3f123aad63
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/c9485a88a2f641b4ae93b49f446dc6e1
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Voltage-gated sodium channels are key players in neuronal excitability and pain signaling. Functional expression of the voltage-gated sodium channel NaV1.7 is under the control of SUMOylated collapsin response mediator protein 2 (CRMP2). Whe
Externí odkaz:
https://doaj.org/article/8b9e30711e1d4322957af6878601721d
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Effective treatment of high-impact pain patients is one of the major stated goals of the National Pain Strategy in the United States. Identification of new targets and mechanisms underlying neuropathic pain will be critical in developing new
Externí odkaz:
https://doaj.org/article/5b9dae28a1e748d580610e9b5e3b061e