Nuclear rupture induced by capillary constriction forces promotes differential effects on metastatic and normal breast cells.

Autor: Perea Paizal J; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK. jp2219@ic.ac.uk.; Division of Cancer Biology, Chester Beatty Laboratories, Institute of Cancer Research, 237 Fulham Road, London, SW6 6JB, UK. jp2219@ic.ac.uk.; Cancer Research UK Convergence Science Centre, Roderic Hill Building, Imperial College London, London, SW7 2BB, UK. jp2219@ic.ac.uk., Au SH; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK.; Cancer Research UK Convergence Science Centre, Roderic Hill Building, Imperial College London, London, SW7 2BB, UK., Bakal C; Division of Cancer Biology, Chester Beatty Laboratories, Institute of Cancer Research, 237 Fulham Road, London, SW6 6JB, UK.; Cancer Research UK Convergence Science Centre, Roderic Hill Building, Imperial College London, London, SW7 2BB, UK.

Publikováno v: Scientific reports [Sci Rep] 2024 Jun 26; Vol. 14 (1), pp. 14793. Date of Electronic Publication: 2024 Jun 26.

Capillary-Scale Hydrogel Microchannel Networks by Wire Templating.

Autor: Kawara S; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK., Cunningham B; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK.; Cancer Research UK Convergence Science Centre, London, SW7 2AZ, UK., Bezer J; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK., Kc N; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK., Zhu J; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK., Tang MX; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK., Ishihara J; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK., Choi JJ; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK., Au SH; Department of Bioengineering, Imperial College London, South Kensington, London, SW7 2AZ, UK.; Cancer Research UK Convergence Science Centre, London, SW7 2AZ, UK.

Publikováno v: Small (Weinheim an der Bergstrasse, Germany) [Small] 2023 Oct; Vol. 19 (42), pp. e2301163. Date of Electronic Publication: 2023 Jun 02.

Microfluidic T Cell Selection by Cellular Avidity.

Autor: Ashby JF; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK., Schmidt J; Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, 1066, Switzerland., Kc N; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK., Kurum A; Institute of Materials Science and Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, 1015, Switzerland., Koch C; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK., Harari A; Department of Oncology UNIL CHUV, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, 1066, Switzerland., Tang L; Institute of Materials Science and Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, 1015, Switzerland.; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, 1015, Switzerland., Au SH; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK.; Cancer Research UK Convergence Science Centre, London, SW7 2AZ, UK.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2022 Aug; Vol. 11 (16), pp. e2200169. Date of Electronic Publication: 2022 Jun 21.

Squeezing through the microcirculation: survival adaptations of circulating tumour cells to seed metastasis.

Autor: Perea Paizal J; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK. j.perea-paizal19@imperial.ac.uk.; Division of Cancer Biology, Chester Beatty Laboratories, Institute of Cancer Research, 237 Fulham Road, London, SW6 6JB, UK. j.perea-paizal19@imperial.ac.uk.; Cancer Research UK Convergence Science Centre, Roderic Hill Building, Imperial College London, London, SW7 2BB, UK. j.perea-paizal19@imperial.ac.uk., Au SH; Department of Bioengineering, Imperial College London, London, SW7 2AZ, UK.; Cancer Research UK Convergence Science Centre, Roderic Hill Building, Imperial College London, London, SW7 2BB, UK., Bakal C; Division of Cancer Biology, Chester Beatty Laboratories, Institute of Cancer Research, 237 Fulham Road, London, SW6 6JB, UK. chris.bakal@icr.ac.uk.; Cancer Research UK Convergence Science Centre, Roderic Hill Building, Imperial College London, London, SW7 2BB, UK. chris.bakal@icr.ac.uk.

Publikováno v: British journal of cancer [Br J Cancer] 2021 Jan; Vol. 124 (1), pp. 58-65. Date of Electronic Publication: 2020 Dec 01.

Effect of Ice Nucleation and Cryoprotectants during High Subzero-Preservation in Endothelialized Microchannels.

Autor: Tessier SN; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States.; Shriners Hospital for Children, 51 Blossom Street, Boston, Massachusetts 02114, United States., Weng L; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States., Moyo WD; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States., Au SH; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States., Wong KHK; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States.; Shriners Hospital for Children, 51 Blossom Street, Boston, Massachusetts 02114, United States., Angpraseuth C; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States., Stoddard AE; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States., Lu C; Massachusetts General Hospital Cancer Center, Harvard Medical School, 149 13th Street, Charlestown, Massachusetts 02129, United States., Nieman LT; Massachusetts General Hospital Cancer Center, Harvard Medical School, 149 13th Street, Charlestown, Massachusetts 02129, United States., Sandlin RD; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States.; Shriners Hospital for Children, 51 Blossom Street, Boston, Massachusetts 02114, United States., Uygun K; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States.; Shriners Hospital for Children, 51 Blossom Street, Boston, Massachusetts 02114, United States., Stott SL; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Massachusetts General Hospital Cancer Center, Harvard Medical School, 149 13th Street, Charlestown, Massachusetts 02129, United States.; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States., Toner M; Center for Engineering in Medicine and BioMEMS Resource Center, Surgical Services, Massachusetts General Hospital, Harvard Medical School, 114 16th Street, Charlestown, Massachusetts 02129, United States.; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States.; Shriners Hospital for Children, 51 Blossom Street, Boston, Massachusetts 02114, United States.

Publikováno v: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2018 Aug 13; Vol. 4 (8), pp. 3006-3015. Date of Electronic Publication: 2018 Jun 26.