Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Atul Varadhachary"'
Publikováno v:
Cancer Research. 83:1630-1630
Improved characterization of the etiology and biology of cancer cells have led to the development of targeted chemotherapeutics, which rely on alterations of particular molecules in cancer cells to exert therapeutic effects. As heterogeneity is an im
Autor:
Stephanie P. Vega, Dev Chatterjee, Atul Varadhachary, Michael Ritchie, Michael Heffernan, Daniel Ciznadija
Publikováno v:
Cancer Research. 83:456-456
While antibody-drug conjugates (ADC) are an attractive modality for targeted cancer therapy, they face limitations. These include a reduced volume of distribution with limited penetration into solid tumors, and an expensive, long and complicated prod
Autor:
Uksha Saini, Julie Hixon, Gisele Rodrigues, Christopher Foley, Leniher Castan Chibas, Ross Hamilton, Wenqing Li, Eric S. Schafer, Susan Rheingold, Michael Heffernan, Philip Breitfeld, Scott Durum, Atul Varadhachary
Publikováno v:
Cancer Research. 83:5664-5664
Successful treatment of ALL has been a major feat of modern medicine. Overall, 5-year survival in pediatric ALL patients approaches 90%, but 10-15% of patients will relapse. In relapse, ALL is still challenging to cure with 5-year overall survival ra
Publikováno v:
medRxiv
COVID-19 has affected billions of people around the world directly or indirectly. The response to the pandemic has focused on preventing the spread of the disease and improving treatment options. Diagnostic technologies have played a key role in this
Autor:
Leo Linbeck, Robbyn Traylor, Rohan Nath, Andrew Malek, Atul Varadhachary, Robert Patrick Garr, John R. Dean, Dev K. Chatterjee, Christopher N. Foley, Juliet Breeze, Andrea Ford Letkeman, David Haug, Javier Garza
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
BackgroundMucosal immunity, including secretory IgA (sIgA), plays an important role in early defenses against respiratory pathogens. Salivary testing, the most convenient way to measure sIgA, has been used to characterize mucosal immune responses to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174665a31717bc613f8bd4eb7443222e
https://doi.org/10.1101/2020.08.07.20170258
https://doi.org/10.1101/2020.08.07.20170258
Autor:
Matthew C. Madison, Dev K. Chatterjee, David B. Corry, Ed Felix, Atul Varadhachary, John S. McMurray, Melissa M. Singh, Joel M. Sederstrom, Brandon Saxton, Pietro Morlacchi, Garbo Mak, Cameron T. Landers, Pijus K. Mandal, Brian E. Gilbert, J. Morgan Knight, Evan Li
Publikováno v:
Journal of Biological Chemistry. 293:10026-10040
Asthma is a chronic inflammatory disease of the lungs and airways and one of the most burdensome of all chronic maladies. Previous studies have established that expression of experimental and human asthma requires the IL-4/IL-13/IL-4 receptor α (IL-
Autor:
Susan R. Rheingold, Wengqing Li, Christopher Foley, Scott K. Durum, Julie A. Hixon, Atul Varadhachary, Eric S. Schafer
Publikováno v:
Cancer Immunology Research. 9:PR014-PR014
With the recent addition of nelarabine to first-line therapy, the overall 5-year survival for pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients approaches 90%. Patient prognosis for those who relapse is heavily dependent on their specifi
Publikováno v:
Journal of Surgical Research. 149:278-286
Background Inflammation is an acute, early process during normal wound healing. Talactoferrin, a recombinant human lactoferrin, can induce the secretion of inflammatory mediators. Materials and methods We measured wound healing activity of topical ta
Autor:
Walter M. Stadler, Eric Jonasch, Robert A. Figlin, Atul Varadhachary, Ronald M. Bukowski, Sandy Srinivas, Rajesh Malik, Teresa G. Hayes
Publikováno v:
Cancer. 113:72-77
BACKGROUND. Talactoferrin (TLF), a recombinant form of human lactoferrin (hLF), is an immunomodulatory iron-binding glycoprotein first identified in breast milk. Its immunomodulatory functions include activation of natural killer (NK) and lymphokine-
Publikováno v:
The Journal of Immunology. 180:6868-6876
Lactoferrin is an 80-kDa iron-binding protein present at high concentrations in milk and in the granules of neutrophils. It possesses multiple activities, including antibacterial, antiviral, antifungal, and even antitumor effects. Most of its antimic