Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Atul Sethi"'
Autor:
Federica Zilli, Pedro Marques Ramos, Priska Auf der Maur, Charly Jehanno, Atul Sethi, Marie‐May Coissieux, Tobias Eichlisberger, Loïc Sauteur, Adelin Rouchon, Laura Bonapace, Joana Pinto Couto, Roland Rad, Michael Rugaard Jensen, Andrea Banfi, Michael B Stadler, Mohamed Bentires‐Alj
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
Abstract Metastasis is the main cause of deaths related to solid cancers. Active transcriptional programmes are known to regulate the metastatic cascade but the molecular determinants of metastatic colonization remain elusive. Using an inducible pigg
Externí odkaz:
https://doaj.org/article/42ad8c50455f42c9bfe8d2e92e8ddc15
Autor:
Tatjana Sajic, Yansheng Liu, Eirini Arvaniti, Silvia Surinova, Evan G. Williams, Ralph Schiess, Ruth Hüttenhain, Atul Sethi, Sheng Pan, Teresa A. Brentnall, Ru Chen, Peter Blattmann, Betty Friedrich, Emma Niméus, Susanne Malander, Aurelius Omlin, Silke Gillessen, Manfred Claassen, Ruedi Aebersold
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2819-2831.e5 (2018)
Cancer is mostly incurable when diagnosed at a metastatic stage, making its early detection via blood proteins of immense clinical interest. Proteomic changes in tumor tissue may lead to changes detectable in the protein composition of circulating bl
Externí odkaz:
https://doaj.org/article/f69a33aae6bb4289a7cf96673277a7c8
Autor:
Milica Vulin, Charly Jehanno, Atul Sethi, Ana Luísa Correia, Milan M. S. Obradović, Joana Pinto Couto, Marie-May Coissieux, Maren Diepenbruck, Bogdan-Tiberius Preca, Katrin Volkmann, Priska Auf der Maur, Alexander Schmidt, Simone Münst, Loïc Sauteur, Michal Kloc, Marta Palafox, Adrian Britschgi, Vincent Unterreiner, Olaf Galuba, Isabelle Claerr, Sandra Lopez-Romero, Giorgio G. Galli, Daniel Baeschlin, Ryoko Okamoto, Savas D. Soysal, Robert Mechera, Walter P. Weber, Thomas Radimerski, Mohamed Bentires-Alj
Publikováno v:
Oncogene. 41:4459-4473
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high cellular plasticity results
Autor:
Baptiste Hamelin, Milan Obradović, Atul Sethi, Michal Kloc, Simone Muenst, Christian Beisel, Katja Eschbach, Hubertus Kohler, Savas Soysal, Marcus Vetter, Walter P. Weber, Michael B. Stadler, Mohamed Bentires-Alj
Metastasis is the leading cause of cancer-related deaths of breast cancer patients. Some cancer cells in a tumour go through successive steps, referred to as the metastatic cascade, and give rise to metastases at a distant site. We know that the plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99dc6f48b63ac737ab99a11b209aacb
https://doi.org/10.1101/2022.10.16.512415
https://doi.org/10.1101/2022.10.16.512415
Autor:
Johannes Sam, Llucia Alberti Servera, Sina Nassiri, Atul Sethi, Alison Ribeiro, Gabrielle Leclercq-Cohen, Petra Schwalie, Tamara Hüsser, Emilio Yangueez, Sylvia Herter, Christian Klein, Pablo Umana, Marina Bacac
Publikováno v:
Cancer Research. 83:4117-4117
T Cell Bispecific Antibodies (TCBs) are potent molecules that induce durable complete remissions with a favorable safety profile in Relapsed Refractory Non Hodgkin Lymphoma patients. Despite the promising clinical efficacy, a proportion of patients e
Autor:
Gordon Bowen, Atul Sethi
The chapter is putting forward the idea that internal marketing is a tool of which there are many to embed a culture to combat cybersecurity threats. This conceptual paper is suggesting that cybersecurity threats are multi-facet and although internal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c250f338e198a89d5fea26a5d99c06fa
https://doi.org/10.4018/978-1-6684-3698-1.ch018
https://doi.org/10.4018/978-1-6684-3698-1.ch018
Autor:
Romain J. Amante, Priska Auf der Maur, Veronica Richina, Atul Sethi, Vytautas Iesmantavicius, Debora Bonenfant, Nicola Aceto, Mohamed Bentires-Alj
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia, 27 (2)
Treatment of metastasis remains a clinical challenge and the majority of breast cancer-related deaths are the result of drug-resistant metastases. The protein tyrosine phosphatase SHP2 encoded by the proto-oncogene PTPN11 promotes breast cancer progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807097728b1a30858a8b656140e41f97
Autor:
Susanne Malander, Ralph Schiess, Atul Sethi, Yansheng Liu, Peter Blattmann, Ruedi Aebersold, Teresa A. Brentnall, Sheng Pan, Aurelius Omlin, Betty Friedrich, Manfred Claassen, Evan G. Williams, Tatjana Sajic, Ruth Hüttenhain, Emma Niméus, Silvia Surinova, Ru Chen, Silke Gillessen, Eirini Arvaniti
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2819-2831.e5 (2018)
Sajic, T, Liu, Y, Arvaniti, E, Surinova, S, Williams, E G, Schiess, R, Hüttenhain, R, Sethi, A, Pan, S, Brentnall, T A, Chen, R, Blattmann, P, Friedrich, B, Niméus, E, Malander, S, Omlin, A, Gillessen, S, Claassen, M & Aebersold, R 2019, ' Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS ', Cell Reports, vol. 23, no. 9, pp. 2819-2831.e5 . https://doi.org/10.1016/j.celrep.2018.04.114
Sajic, T, Liu, Y, Arvaniti, E, Surinova, S, Williams, E G, Schiess, R, Hüttenhain, R, Sethi, A, Pan, S, Brentnall, T A, Chen, R, Blattmann, P, Friedrich, B, Niméus, E, Malander, S, Omlin, A, Gillessen, S, Claassen, M & Aebersold, R 2019, ' Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS ', Cell Reports, vol. 23, no. 9, pp. 2819-2831.e5 . https://doi.org/10.1016/j.celrep.2018.04.114
Summary Cancer is mostly incurable when diagnosed at a metastatic stage, making its early detection via blood proteins of immense clinical interest. Proteomic changes in tumor tissue may lead to changes detectable in the protein composition of circul
Autor:
Nenad Manevski, Baptiste Hamelin, Hubertus Kohler, Marie-May Coissieux, Joana Pinto Couto, Alexander Schmidt, Mohamed Bentires-Alj, Ryoko Okamoto, Simone Münst, Atul Sethi, Milan M. S. Obradović
Publikováno v:
Nature
Diversity within or between tumours and metastases (known as intra-patient tumour heterogeneity) that develops during disease progression is a serious hurdle for therapy(1-3). Metastasis is the fatal hallmark of cancer and the mechanisms of colonizat
Autor:
Ruedi Aebersold, Ulrike Kusebauch, Nathalie Selevsek, Christine Carapito, Emma Niméus-Malmström, Terry Farrah, Robert L. Moritz, Atul Sethi, Hannes L. Röst, Eric W. Deutsch, Ruth Hüttenhain, Oliver Rinner, Martin Soste
Publikováno v:
Science Translational Medicine
The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in translational research. This is particularly the case for the validation of protein biomarkers; the lack of accurate, reproducible, and sensitive assays for most p