Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Atul R Mahableshwarkar"'
Autor:
Donald L. Gilbert, Jordan S. Dubow, Timothy M. Cunniff, Stephen P. Wanaski, Sarah D. Atkinson, Atul R. Mahableshwarkar
Publikováno v:
Pediatrics. 151
BACKGROUND AND OBJECTIVES All US Food and Drug Administration-approved medications for Tourette syndrome are antipsychotics, and their use is limited by the risk of weight gain, metabolic changes, and drug-induced movement disorders. Several small tr
Autor:
Atul R. Mahableshwarkar, Judith Xu, George G. Nomikos, Paula L. Jacobsen, John Affinito, Elin Heldbo Reines
Publikováno v:
CNS Spectrums. 25:352-362
ObjectivesThis study aimed to evaluate the risk of suicidal ideation and behavior associated with vortioxetine treatment in adults with major depressive disorder (MDD).MethodsSuicide-related events were evaluated post hoc using 2 study pools: one sho
Publikováno v:
Psychiatry and Clinical Neurosciences. 72:64-72
Aim This study assessed the efficacy and safety of vortioxetine in adults with major depressive disorder. Methods In this double-blind, placebo-controlled study, 600 patients with major depressive disorder were randomly assigned (1:1:1:1) to receive
Autor:
Atul R. Mahableshwarkar, Gary S. Sachs, Joseph R. Calabrese, Xinxin Dong, Adedeji Adefuye, Thomas A. Macek, Kumar Budur, Elizabeth Hanson
Publikováno v:
Journal of Affective Disorders. 221:275-282
Background The optimal long-term management strategy for bipolar I disorder patients is not yet established. Evidence supports the rationale for circadian rhythm regulation to prevent mood episode relapse in bipolar patients. This study evaluated the
Consistency checks to improve measurement with the Montgomery-Asberg Depression Rating Scale (MADRS)
Autor:
Felice Ockun, Christian Yavorsky, Joyce Tsai, Atul R. Mahableshwarkar, Gretchen Friedberger, Janet B. W. Williams, Colin L. Sauder, Brianne Brown, Jonathan Rabinowitz, Bruce J Kinon, Mads Dalsgaard, Nina R. Schooler, Isctm Algorithms, Daniel Lee, Nina Engelhardt
Publikováno v:
Journal of affective disorders. 256
International Society for CNS Clinical Trials and Methodology convened an expert Working Group that assembled consistency/inconsistency flags for the Montgomery-Asberg Depression Rating Scale (MADRS). Twenty-two flags were identified. Seven flags are
Publikováno v:
European Neuropsychopharmacology. 26:979-993
The efficacy and safety of vortioxetine, an antidepressant approved for the treatment of adults with major depressive disorder (MDD), was studied in 11 randomized, double-blind, placebo-controlled trials of 6/8 weeks׳ treatment duration. An aggregat
Autor:
Maurizio, Fava, Atul R, Mahableshwarkar, William, Jacobson, Wei, Zhong, Richard Se, Keefe, Christina Kurre, Olsen, Judith, Jaeger
Publikováno v:
Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. 30(3)
Cognitive impairments, such as memory deficits and executive impairment, are common among patients with major depressive disorder (MDD) and can be captured with objective or subjective assessments. The aim of this post-hoc analysis of the CONNECT stu
Autor:
Xinxin Dong, Paul Goldsmith, Maggie McCue, Elizabeth Hanson, Atul R. Mahableshwarkar, John Affinito, Thomas A. Macek
Publikováno v:
Schizophrenia research. 204
Introduction TAK-063 is a potent, selective inhibitor of phosphodiesterase 10A, an enzyme selectively expressed in medium spiny neurons of the striatum. This randomized, parallel-group study evaluated the efficacy and safety of 20-mg daily TAK-063 ve
Publikováno v:
The Journal of Sexual Medicine. 12:2036-2048
Introduction Sexual dysfunction is common with serotonergic antidepressants, including selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs), and does not resolve in most patients. Vortioxetine, an
Autor:
Breanna Essoi, Haridarshan Patel, Atul R Mahableshwarkar, Jennifer C. Samp, Jiao Yang, Jonathan Kurlander, Kasem S Akhras, Valery Walker
Publikováno v:
Journal of Managed Care & Specialty Pharmacy. 21:742-752
Major depressive disorder is one of the most common and disabling mental health disorders and is associated with substantial costs in terms of direct health care utilization and workplace productivity. Cognitive dysfunction, which alone substantially