Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Atul Kondaskar"'
Autor:
Guus M Bol, Farhad Vesuna, Min Xie, Jing Zeng, Khaled Aziz, Nishant Gandhi, Anne Levine, Ashley Irving, Dorian Korz, Saritha Tantravedi, Marise R Heerma van Voss, Kathleen Gabrielson, Evan A Bordt, Brian M Polster, Leslie Cope, Petra van der Groep, Atul Kondaskar, Michelle A Rudek, Ramachandra S Hosmane, Elsken van der Wall, Paul J van Diest, Phuoc T Tran, Venu Raman
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 648-669 (2015)
Abstract Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which is overexpressed in many cancer types including
Externí odkaz:
https://doaj.org/article/e07c631e5fec4cceaa092c7b616dd2dc
Autor:
Min Xie, Ramachandra S. Hosmane, Dorian Korz, Guus M. Bol, Phuoc T. Tran, Farhad Vesuna, Leslie Cope, Atul Kondaskar, Brian M. Polster, Ashley Irving, Marise R. Heerma van Voss, Jing Zeng, Michelle A. Rudek, Petra van der Groep, Nishant Gandhi, Evan A. Bordt, Anne Levine, Elsken van der Wall, Paul J. van Diest, Saritha Tantravedi, Venu Raman, Kathleen L. Gabrielson, Khaled Aziz
Publikováno v:
Embo Molecular Medicine, 7(5), 648. Wiley-Blackwell
EMBO Molecular Medicine
EMBO Molecular Medicine
Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which is overexpressed in many cancer types including lung can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5551fb038398fb1155edc9fc376069a2
https://dspace.library.uu.nl/handle/1874/331617
https://dspace.library.uu.nl/handle/1874/331617
Publikováno v:
Expert Opinion on Therapeutic Patents. 16:733-751
Gonadotropin releasing hormone (GnRH), also known as luteinising hormone releasing hormone (LHRH), is a decapeptide released from the hypothalamus that binds to the G-protein-coupled GnRH receptor located on the pituitary gland. This receptor plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8c5e49738205e015824ed6d60683613
https://doi.org/10.1517/13543776.16.6.733
https://doi.org/10.1517/13543776.16.6.733
Publikováno v:
Tetrahedron. 60:9085-9091
Montmorillonite K 10 efficiently catalyses the opening of epoxide rings by amines in high yields with excellent regio- and diastereo-selectivities under solvent-free conditions at room temperature affording an improved process for synthesis of 2-amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f8018e3dc43c2c481c97f7d390eaecc
https://doi.org/10.1016/j.tet.2004.07.077
https://doi.org/10.1016/j.tet.2004.07.077
Autor:
Ramachandra S. Hosmane, Rena G. Lapidus, Shilpi Kondaskar, Brandon Carter-Cooper, Atul Kondaskar, Martin J. Edelman, James C. Fishbein, Mariola Sadowska
Judicial structural modifications of 5:7-fused ring-expanded nucleosides (RENs), based on molecular modeling studies with one of its known targets, human RNA helicase (hDDX3), led to the lead, novel, 5:7-5-fused tricyclic heterocycle (1). The latter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6ec925160d324142ca6b3871590ce1
https://europepmc.org/articles/PMC3546142/
https://europepmc.org/articles/PMC3546142/
Autor:
Ramachandra S. Hosmane, Nidal Muvarak, Guus M. Bol, Raj Kumar, Rena G. Lapidus, James C. Fishbein, Shilpi Kondaskar, Atul Kondaskar, Martin J. Edelman, Farhad Vesuna, Mariola Sadowska, Venu Raman
Synthesis of a series of novel, broad-spectrum anti-cancer agents containing the tricyclic 5:7:5-fused diimidazo[4,5-d:4',5'-f][1,3]diazepine ring system is reported. Compounds 1, 2, 8, 11, and 12 in the series show promising in vitro antitumor activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545790ac0e7786abb795595ca41b25b1
https://europepmc.org/articles/PMC3092706/
https://europepmc.org/articles/PMC3092706/
Publikováno v:
ChemInform. 37
Carboxylic acids are converted to benzothiazoles in a one-pot reaction with thionyl chloride followed by treatment with 2-aminothiophenol under acid- and catalyst-free conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b990a515b5e6e9b60f4c71eac1d57b04
https://doi.org/10.1002/chin.200607139
https://doi.org/10.1002/chin.200607139
Autor:
Nitya Anand, Jung B. Gupta, Sankaranarayanan Dharmarajan, Atul Kondaskar, Pks Sarma, Anita Chugh, Kamna Nanda, Praful Gupta, Neelima Sinha, Laxminarayan G. Hedge, Sanjay Jain
Publikováno v:
Bioorganicmedicinal chemistry letters.
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48472b2c2ad37eaf987e5c71332cb218
https://pubmed.ncbi.nlm.nih.gov/16275082
https://pubmed.ncbi.nlm.nih.gov/16275082
Publikováno v:
ChemInform. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d5b710f777adcb6988ddb2d9c949766
https://doi.org/10.1002/chin.200501075
https://doi.org/10.1002/chin.200501075
Publikováno v:
ChemInform. 35
Lithium bromide has been found to be an inexpensive and efficient catalyst for the opening of epoxide rings by amines, and this provides an environmentally friendly method for the synthesis of β-amino alcohols. Aromatic and aliphatic amines react wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cad7a50f43dd3b8d4d1dfc1d44a9ecd
https://doi.org/10.1002/chin.200448096
https://doi.org/10.1002/chin.200448096