Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Attya Omer"'
Autor:
Martina Fiumara, Samuele Ferrari, Attya Omer-Javed, Stefano Beretta, Luisa Albano, Daniele Canarutto, Angelica Varesi, Chiara Gaddoni, Chiara Brombin, Federica Cugnata, Erika Zonari, Matteo Maria Naldini, Matteo Barcella, Bernhard Gentner, Ivan Merelli, Luigi Naldini
Publikováno v:
HemaSphere, Vol 7, p e6237653 (2023)
Externí odkaz:
https://doaj.org/article/4dacf51b000c4c6baa7cbba5fcb5b5e7
Autor:
Samuele Ferrari, Valentina Vavassori, Daniele Canarutto, Aurelien Jacob, Maria Carmina Castiello, Attya Omer Javed, Pietro Genovese
Publikováno v:
Frontiers in Genome Editing, Vol 3 (2021)
In the field of hematology, gene therapies based on integrating vectors have reached outstanding results for a number of human diseases. With the advent of novel programmable nucleases, such as CRISPR/Cas9, it has been possible to expand the applicat
Externí odkaz:
https://doaj.org/article/b32545ce26e24840b29d5b4f310a9104
Autor:
Attya Omer Javed, Yun Li, Julien Muffat, Kuan-Chung Su, Malkiel A. Cohen, Tenzin Lungjangwa, Patrick Aubourg, Iain M. Cheeseman, Rudolf Jaenisch
Publikováno v:
Cell Reports, Vol 25, Iss 2, Pp 368-382.e5 (2018)
Summary: Most genes mutated in microcephaly patients are expressed ubiquitously, and yet the brain is the only major organ compromised in most patients. Why the phenotype remains brain specific is poorly understood. In this study, we used in vitro di
Externí odkaz:
https://doaj.org/article/2f620656beed49f08740a12579eca9ce
Autor:
Li, Yun, Muffat, Julien, Javed, Attya Omer, Keys, Heather R., Lungjangwa, Tenzin, Bosch, Irene, Khan, Mehreen, Virgilio, Maria C., Gehrke, Lee, Sabatini, David M., Jaenisch, Rudolf
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 May 01. 116(19), 9527-9532.
Externí odkaz:
https://www.jstor.org/stable/26705140
Akademický článek
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Autor:
Attya Omer-Javed, Gabriele Pedrazzani, Luisa Albano, Sherash Ghaus, Claire Latroche, Maura Manzi, Samuele Ferrari, Martina Fiumara, Aurelien Jacob, Valentina Vavassori, Alessandro Nonis, Daniele Canarutto, Luigi Naldini
Publikováno v:
Cell. 185:2248-2264.e21
Hematopoietic stem/progenitor cell gene therapy (HSPC-GT) is proving successful to treat several genetic diseases. HSPCs are mobilized, harvested, genetically corrected ex vivo, and infused, after the administration of toxic myeloablative conditionin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532c934ca5f6113d1af845da14286e3b
https://doi.org/10.1016/j.cell.2022.04.039
https://doi.org/10.1016/j.cell.2022.04.039
Autor:
Kirsten Schneider, Martin Trapecar, Devon S. Svoboda, Douglas A. Lauffenburger, Samuel Mildrum, Meelim J. Lee, Rudolf Jaenisch, Linda G. Griffith, Austin Hendricks, Jason Velazquez, Julien Muffat, Pierre Sphabmixay, Stuart S. Levine, Emile Wogram, Attya Omer, David L. Trumper, Catherine Communal, Charles W. Wright, Tenzin Lungjangwa
Publikováno v:
Science Advances
Engineered model of the human gut-liver-brain axis can be used to study the link between the microbiome and Parkinson’s disease.
Slow progress in the fight against neurodegenerative diseases (NDs) motivates an urgent need for highly controlled
Slow progress in the fight against neurodegenerative diseases (NDs) motivates an urgent need for highly controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549f6cea67252b7d64f64ef965b823c9
https://pubmed.ncbi.nlm.nih.gov/33514545
https://pubmed.ncbi.nlm.nih.gov/33514545
Autor:
Attya Omer, Ivan Merelli, Luisa Albano, Martina Fiumara, Stefano Beretta, Samuele Ferrari, Luigi Naldini
Publikováno v:
Blood. 138:3976-3976
Genome editing represents a promising tool to manipulate human hematopoietic stem and progenitor cells (HSPCs) opening the possibility to correct hematopoietic diseases avoiding the risk of insertional mutagenesis and uncontrolled expression of the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7a5cb39a541716b4363a249738324cf
https://doi.org/10.1182/blood-2021-147700
https://doi.org/10.1182/blood-2021-147700
Autor:
Lee Gehrke, Tenzin Lungjangwa, Mehreen Khan, Maria C. Virgilio, Heather R. Keys, Yun Li, Irene Bosch, Attya Omer Javed, Julien Muffat, David M. Sabatini, Rudolf Jaenisch
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(19)
Zika virus (ZIKV) is a neurotropic and neurovirulent arbovirus that has severe detrimental impact on the developing human fetal brain. To date, little is known about the factors required for ZIKV infection of human neural cells. We identified ZIKV ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b787b8dc8ba1d024712f6017f7c567a4
https://pubmed.ncbi.nlm.nih.gov/31019072
https://pubmed.ncbi.nlm.nih.gov/31019072
Akademický článek
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