Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Attila Szemzo"'
Autor:
L. Kovács, Béla Fekete, András Falus, Attila Szemzo, Klára Tamássy, Katalin Pálóczi, Valeria Lia Varga, János Sági
Publikováno v:
Immunology Letters. 58:181-190
Based on cDNA sequence data epsilon chain-specific antisense oligonucleotides were synthesized and checked on in vitro IgE production. Using peripheral blood cells from a hypereosinophilic patient and a human IgE myeloma cell line, U266, marked reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7caf7d4e663bf6b0572fe3710def14
https://doi.org/10.1016/s0165-2478(97)00082-5
https://doi.org/10.1016/s0165-2478(97)00082-5
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 13:999-1006
X-form is an unusual double helix of DNA adopted by poly(dA-dT) or (dT-dA)4 at high concentrations of CsF. On the other hand, poly(dA), poly(dT), (dA-dT)4 and most other DNAs do not adopt this conformer. Here we demonstrate that the X-form is strongl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce25c105cdabc4345a2d0a697d0a8ce
https://doi.org/10.1080/07391102.1996.10508914
https://doi.org/10.1080/07391102.1996.10508914
Publikováno v:
International Journal of Biological Macromolecules. 17:239-246
Acyclic analogues of oligothymidylate and oligoadenylate and their alternating copolymers were synthesized to study their thermal melting, their stability against snake venom phosphodiesterase and their primer/template properties using the Klenow fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7d87e17efb7b494bee83bac5c33741
https://doi.org/10.1016/0141-8130(95)98150-w
https://doi.org/10.1016/0141-8130(95)98150-w
Autor:
László Ötvös, Janos Sagi, Eva Ruff, Gyula Sági, Attila Szemzo, Katalin Ebinger, Anna Szabolcs
Publikováno v:
Tetrahedron Letters. 34:2191-2194
Properties of oligodeoxynucleotides essential for the antisense effect can be favourably modified by substitution of the heterocyclic base moiety. This is shown here for duplex stability by 5 alkyl, 5-(1-alkenyl) and 5-(1-alkynyl) substitution of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc8681e10dd477276308a2141e9e367
https://doi.org/10.1016/s0040-4039(00)60379-9
https://doi.org/10.1016/s0040-4039(00)60379-9
Publikováno v:
Journal of Chromatography A. 506:35-44
A series of 5-alkyl-, 5-alkenyl- and 5-alkynyl-substituted deoxyuridines and their triphosphate derivatives were synthesized and studied in DNA polymerase reactions. The initial rate of incorporation of the derivatives catalysed by Klenow fragment DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da5cccae2f48f8f8eed5c7bea6b704f0
https://doi.org/10.1016/s0021-9673(01)91565-1
https://doi.org/10.1016/s0021-9673(01)91565-1
Publikováno v:
Tetrahedron Letters. 31:1463-1466
5'-O-(dimethoxytrityl)-(+)-carbocyclic thymidine 1 is converted into different 3'-substituted intermediates 2a-c following standard procedures. From these compounds stereochemically pure carbocyclic oligothymidylates 4 are obtained using solid phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::904e262f30cebca0d949107bb3fc8b8a
https://doi.org/10.1016/s0040-4039(00)88833-4
https://doi.org/10.1016/s0040-4039(00)88833-4
Publikováno v:
Nucleic Acids Research. 18:2133-2140
We report here spectroscopic and biochemical data of a novel series of sugar-modified oligodeoxy-nucleotides, the carbocyclic oligothymidylates, c(dT)3-20. In c(dT)n a methylene group has been substituted for the oxygen atom of the deoxyribose ring o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d611eda43f801d8199ca0dff09c03c
https://doi.org/10.1093/nar/18.8.2133
https://doi.org/10.1093/nar/18.8.2133
Publikováno v:
Nucleosidesnucleotides. 18(6-7)
Two series of alternating ODNs containing 5-n.alkyl-, alkenyl- and alkynyl-dU and -dC units have been prepared in order to study the kinetics of their hydrolysis by SV PDE and human serum, respectively. Both in (r5dUpdA)10 and (r5dCpdG)6 series the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b760e81b3e5bc41b73f44d86f84b293
https://pubmed.ncbi.nlm.nih.gov/10474242
https://pubmed.ncbi.nlm.nih.gov/10474242
Some biochemical properties of an acyclic oligonucleotide analogue. A plausible ancestor of the DNA?
Publikováno v:
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life. 23(2)
As acyclic oligonucleotides have been suggested as a primitive model of DNA or RNA in prebiotic times, we compared some biochemical properties of these analogues to that of natural ones. Firstly, an acyclic analogue of deoxyribonucleoside triphosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47741420ee73ccf7ce8afa3fd79d757
https://pubmed.ncbi.nlm.nih.gov/8384707
https://pubmed.ncbi.nlm.nih.gov/8384707
Publikováno v:
International journal of biological macromolecules. 13(6)
The B-to-Z conformational transition of poly(dG-dC) is highly promoted by 5-methyl substitution of the dC moiety, i.e. in poly(dG-methyl5dC). By the synthesis of a new poly(dG-dC) analogue, poly(dG-ethyl5dC), the effect of a longer alkyl-chain substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60ab3c2e788787a6804ef82a0d9f354
https://pubmed.ncbi.nlm.nih.gov/1772823
https://pubmed.ncbi.nlm.nih.gov/1772823