Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Attila Gácser"'
Autor:
Leandro Honorato, Jhon J. Artunduaga Bonilla, Alessandro F. Valdez, Susana Frases, Glauber Ribeiro de Sousa Araújo, Albaniza Liuane Ribeiro do Nascimento Sabino, Natalia Martins da Silva, Larissa Ribeiro, Marina da Silva Ferreira, Julio Kornetz, Marcio L. Rodrigues, Iain Cunningham, Neil A. R. Gow, Attila Gacser, Allan J. Guimarães, Fabianno F. Dutra, Leonardo Nimrichter
Publikováno v:
mSphere, Vol 9, Iss 8 (2024)
ABSTRACT Systemic candidiasis remains a significant public health concern worldwide, with high mortality rates despite available antifungal drugs. Drug-resistant strains add to the urgency for alternative therapies. In this context, vaccination has r
Externí odkaz:
https://doaj.org/article/1dc59086ea434c24bf763a412b238806
Autor:
Eszter Bokor, Judit Ámon, Mónika Varga, András Szekeres, Zsófia Hegedűs, Tamás Jakusch, Zsolt Szakonyi, Michel Flipphi, Csaba Vágvölgyi, Attila Gácser, Claudio Scazzocchio, Zsuzsanna Hamari
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A novel nicotinate degradation pathway is described in Aspergillus nidulans, with metabolic products identified that were not previously found in prokaryotic species. This is the first such pathway to be described in a eukaryote.
Externí odkaz:
https://doaj.org/article/9e9ab06af27f41c9be825dfd21fdd68a
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2571-2582 (2021)
Candida infections are the most prevalent cause of serious human mycoses and are the third most common pathogens isolated from bloodstream infections in hospitalized patients. C. parapsilosis is a member of the non-albicans spp., which have a predile
Externí odkaz:
https://doaj.org/article/9933457a41054294a57b23a8a19d6034
Autor:
Tamás Takács, Mihály Tibor Németh, Flóra Bohner, Csaba Vágvölgyi, Ferenc Jankovics, Duncan Wilson, Attila Gácser
Publikováno v:
Open Biology, Vol 12, Iss 7 (2022)
The zinc restriction and zinc toxicity are part of host defence, called nutritional immunity. The crucial role of zinc homeostasis in microbial survival within a host is established, but little is known about these processes in the opportunistic huma
Externí odkaz:
https://doaj.org/article/aa1a93b13ae04289b1ca7084eb2f5285
Autor:
Máté Vadovics, Jemima Ho, Nóra Igaz, Róbert Alföldi, Dávid Rakk, Éva Veres, Balázs Szücs, Márton Horváth, Renáta Tóth, Attila Szücs, Andrea Csibi, Péter Horváth, László Tiszlavicz, Csaba Vágvölgyi, Joshua D. Nosanchuk, András Szekeres, Mónika Kiricsi, Rhonda Henley-Smith, David L. Moyes, Selvam Thavaraj, Rhys Brown, László G. Puskás, Julian R. Naglik, Attila Gácser
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Oral squamous cell carcinoma (OSCC) is associated with oral Candida albicans infection, although it is unclear whether the fungus promotes the genesis and progression of OSCC or whether cancer facilitates fungal growth. In this study, we inv
Externí odkaz:
https://doaj.org/article/93f44f6d7ed54b7a813a14b3df629848
Autor:
Zsolt Balla, Eszter Sára Kormányos, Balázs Kui, Emese Réka Bálint, Gabriella Fűr, Erik Márk Orján, Béla Iványi, László Vécsei, Ferenc Fülöp, Gabriella Varga, András Harazin, Vilmos Tubak, Mária A. Deli, Csaba Papp, Attila Gácser, Tamara Madácsy, Viktória Venglovecz, József Maléth, Péter Hegyi, Lóránd Kiss, Zoltán Rakonczay
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The pathophysiology of acute pancreatitis (AP) is not well understood, and the disease does not have specific therapy. Tryptophan metabolite L-kynurenic acid (KYNA) and its synthetic analogue SZR-72 are antagonists of the N-methyl-D-aspartate recepto
Externí odkaz:
https://doaj.org/article/0139ec1a8ec142cd8e979869ce158f65
Autor:
Erik Zajta, Katalin Csonka, Adél Tóth, Laszló Tiszlavicz, Tamás Németh, Anita Orosz, Ádám Novák, Máté Csikós, Csaba Vágvölgyi, Attila Mócsai, Attila Gácser
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT The spleen tyrosine kinase (Syk) and the downstream adaptor protein CARD9 are crucial signaling molecules in antimicrobial immunity. Candida parapsilosis is an emerging fungal pathogen with a high incidence in neonates, while Candida albican
Externí odkaz:
https://doaj.org/article/c011d03ff5bf4b71b4e56284953a58df
Autor:
Márton Horváth, Gábor Nagy, Nóra Zsindely, László Bodai, Péter Horváth, Csaba Vágvölgyi, Joshua D. Nosanchuk, Renáta Tóth, Attila Gácser
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
A relatively new topic within the field of immunology involves the role of miRNAs in innate as well as adaptive immune response regulation. In recent years, posttranscriptional regulation of host-pathogenic fungal interactions through miRNAs was also
Externí odkaz:
https://doaj.org/article/f310da977f33481e82f5c1f1a5cc1d5e
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 970-975 (2019)
Eicosanoids are bioactive lipid mediators generated in almost all mammalian cells from the oxidation of arachidonic acid and other related twenty-carbon polyunsaturated fatty acids (PUFA). Eicosanoids regulate various physiological functions, includi
Externí odkaz:
https://doaj.org/article/e3abe73ad3a14083b12ea878d209b9ce
Autor:
Tanmoy Chakraborty, Ernst Thuer, Marieke Heijink, Renáta Tóth, László Bodai, Csaba Vágvölgyi, Martin Giera, Toni Gabaldón, Attila Gácser
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1019-1035 (2018)
Lipid mediators, derived from arachidonic acid metabolism, play an important role in immune regulation. The functions of bioactive eicosanoids range from modulating cytokine signaling and inflammasome formation to anti-inflammatory and pro-resolving
Externí odkaz:
https://doaj.org/article/b743a4e9447c4e9bb83919e16e7cb950