Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Attila Brunyanszki"'
Autor:
Bartosz Szczesny, Michela Marcatti, Akbar Ahmad, Mauro Montalbano, Attila Brunyánszki, Sofia-Iris Bibli, Andreas Papapetropoulos, Csaba Szabo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract This report identifies mitochondrial DNA (mtDNA) as a target and active mediator that links low-level oxidative stress to inflammatory response in pulmonary epithelial cells. Extrusion of mtDNA into the bronchoalveolar lavage fluid occurs as
Externí odkaz:
https://doaj.org/article/7eeba3dbce074d0b8540463c8f17b8c1
Autor:
Judit Márton, Tamás Fodor, Lilla Nagy, András Vida, Gréta Kis, Attila Brunyánszki, Miklós Antal, Bernhard Lüscher, Péter Bai
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0187789 (2018)
Poly(ADP-ribose) polymerase (PARP)10 is a PARP family member that performs mono-ADP-ribosylation of target proteins. Recent studies have linked PARP10 to metabolic processes and metabolic regulators that prompted us to assess whether PARP10 influence
Externí odkaz:
https://doaj.org/article/063032bef69c497e8f46306661aec995
Autor:
Gábor Oláh, Bartosz Szczesny, Attila Brunyánszki, Isabel A López-García, Domokos Gerö, Zsolt Radák, Csaba Szabo
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134227 (2015)
Poly(ADP-ribose) polymerase 1 (PARP-1), the major isoform of the poly (ADP-ribose) polymerase family, is a constitutive nuclear and mitochondrial protein with well-recognized roles in various essential cellular functions such as DNA repair, signal tr
Externí odkaz:
https://doaj.org/article/1b010de0ceaa45bf9fe28483f525b90f
Autor:
Bartosz Szczesny, Attila Brunyánszki, Akbar Ahmad, Gabor Oláh, Craig Porter, Tracy Toliver-Kinsky, Labros Sidossis, David N Herndon, Csaba Szabo
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143730 (2015)
Severe thermal injury induces a pathophysiological response that affects most of the organs within the body; liver, heart, lung, skeletal muscle among others, with inflammation and hyper-metabolism as a hallmark of the post-burn damage. Oxidative str
Externí odkaz:
https://doaj.org/article/d0083c7da34e44d096956e337fa3e5ac
Autor:
Lilla Nagy, Tibor Docsa, Magdolna Szántó, Attila Brunyánszki, Csaba Hegedűs, Judit Márton, Bálint Kónya, László Virág, László Somsák, Pál Gergely, Péter Bai
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69420 (2013)
Glycogen phosphorylase (GP) catalyzes the breakdown of glycogen and largely contributes to hepatic glucose production making GP inhibition an attractive target to modulate glucose levels in diabetes. Hereby we present the metabolic effects of a novel
Externí odkaz:
https://doaj.org/article/313a746639f7435f87eba45d50e39286
Autor:
Bartosz Szczesny, Csaba Szabó, Kazunori Yanagi, Andreas Papapetropoulos, Ciro Coletta, Attila Brunyanszki, Ester Rios, Gabor Olah, Akbar Ahmad, Katalin Módis
Publikováno v:
Molecular Medicine. 21:1-14
Hydrogen sulfide (H2S), as a reducing agent and an antioxidant molecule, exerts protective effects against hyperglycemic stress in the vascular endothelium. The mitochondrial enzyme 3-mercaptopyruvate sulfurtransferase (3-MST) is an important biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abdb11bdbcdcd3cfcfcf76bb9241383
https://doi.org/10.2119/molmed.2015.00035
https://doi.org/10.2119/molmed.2015.00035
Autor:
Attila Brunyanszki, Bartosz Szczesny, Katalin Erdelyi, Reinaldo Salomão, Gabor Olah, David N. Herndon, Csaba Szabó
Publikováno v:
Molecular Medicine. 21:666-675
The classical role of hemoglobin in the erythrocytes is to carry oxygen from the lungs to the tissues via the circulation. However, hemoglobin also acts as a redox regulator and as a scavenger of the gaseous mediators nitric oxide (NO) and hydrogen s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cf15512959a49e443bf83c3619a6e0
https://doi.org/10.2119/molmed.2015.00187
https://doi.org/10.2119/molmed.2015.00187
Publikováno v:
Nucleic Acids Research
The positive role of PARP1 in regulation of various nuclear DNA transactions is well established. Although a mitochondrial localization of PARP1 has been suggested, its role in the maintenance of the mitochondrial DNA is currently unknown. Here we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6ef7c1beb13437800adb63f045315b
http://europepmc.org/articles/PMC4245951
http://europepmc.org/articles/PMC4245951
Autor:
Attila Brunyanszki, László Virág, Borbála Kiss, Lilla Nikoletta Nagy, György Vámosi, Péter Bai, Pál Gergely, Tamás Fodor, Judit Márton, Magdolna Szántó
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1842:594-602
Poly(ADP-ribose) polymerase-2 (PARP-2) is acknowledged as a DNA repair enzyme. However, recent investigations have attributed unique roles to PARP-2 in metabolic regulation in the liver. We assessed changes in hepatic lipid homeostasis upon the delet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a534bd223e7343b3e88b970a9aed8a2a
https://doi.org/10.1016/j.bbadis.2013.12.006
https://doi.org/10.1016/j.bbadis.2013.12.006
Autor:
Gréta Kis, Attila Brunyanszki, Judit Márton, Péter Bai, Bernhard Lüscher, András Vida, Miklós Antal, Lilla Nikoletta Nagy, Tamás Fodor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0187789 (2018)
PLOS ONE 13(1), e0187789 (2018). doi:10.1371/journal.pone.0187789
PLoS ONE, Vol 13, Iss 1, p e0187789 (2018)
PLOS ONE 13(1), e0187789 (2018). doi:10.1371/journal.pone.0187789
Poly(ADP-ribose) polymerase (PARP)10 is a PARP family member that performs mono-ADP-ribosylation of target proteins. Recent studies have linked PARP10 to metabolic processes and metabolic regulators that prompted us to assess whether PARP10 influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f8bebb502303fb6e8c0fca86ee6e6a
https://pubmed.ncbi.nlm.nih.gov/29293500
https://pubmed.ncbi.nlm.nih.gov/29293500