Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Attila, Braun"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Galectins are carbohydrate-binding proteins that regulate many cellular functions including proliferation, adhesion, migration, and phagocytosis. Increasing experimental and clinical evidence indicates that galectins influence many steps of cancer de
Externí odkaz:
https://doaj.org/article/09b507b7d0994ac7a291c72ec26bf62c
Autor:
Chao Han, Pengxuan Ren, Medina Mamtimin, Linus Kruk, Edita Sarukhanyan, Chenyu Li, Hans-Joachim Anders, Thomas Dandekar, Irena Krueger, Margitta Elvers, Silvia Goebel, Kristin Adler, Götz Münch, Thomas Gudermann, Attila Braun, Elmina Mammadova-Bach
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 423 (2023)
Glycoprotein VI (GPVI) is a platelet-specific receptor for collagen and fibrin, regulating important platelet functions such as platelet adhesion and thrombus growth. Although the blockade of GPVI function is widely recognized as a potent anti-thromb
Externí odkaz:
https://doaj.org/article/baa6ba13cc5e43369b4b0d501f8dc336
Autor:
Johannes Balkenhol, Kristin V. Kaltdorf, Elmina Mammadova-Bach, Attila Braun, Bernhard Nieswandt, Marcus Dittrich, Thomas Dandekar
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Understanding the molecular mechanisms of platelet activation and aggregation is of high interest for basic and clinical hemostasis and thrombosis research. The central platelet protein interaction network is involved in major res
Externí odkaz:
https://doaj.org/article/760b9ec82a144097ad7cb901477a4c76
Autor:
Medina Mamtimin, Akif Pinarci, Chao Han, Attila Braun, Hans-Joachim Anders, Thomas Gudermann, Elmina Mammadova-Bach
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Extracellular DNA may serve as marker in liquid biopsies to determine individual diagnosis and prognosis in cancer patients. Cell death or active release from various cell types, including immune cells can result in the release of DNA into the extrac
Externí odkaz:
https://doaj.org/article/19f3ea51dc35449dac6132cd65dd90fb
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Although platelets are critically involved in thrombosis and hemostasis, experimental and clinical evidence indicate that platelets promote tumor progression and metastasis through a wide range of physical and functional interactions between platelet
Externí odkaz:
https://doaj.org/article/fc68906f99b243fe8f339677f3df0e0a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Clotting and inflammation are effective danger response patterns positively selected by evolution to limit fatal bleeding and pathogen invasion upon traumatic injuries. As a trade-off, thrombotic, and thromboembolic events complicate severe forms of
Externí odkaz:
https://doaj.org/article/0acf0d101d0744258b35199e86589d1c
Autor:
Inga Scheller, Simon Stritt, Sarah Beck, Bing Peng, Irina Pleines, Katrin G. Heinze, Attila Braun, Oliver Otto, Robert Ahrends, Albert Sickmann, Markus Bender, Bernhard Nieswandt
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
Platelet aggregate formation is a multistep process involving receptor-mediated, as well as biomechanical, signaling cascades, which are highly dependent on actin dynamics. We have previously shown that actin depolymerizing factor (ADF)/n-cofilin and
Externí odkaz:
https://doaj.org/article/3210c51d380148f59dedc478c1e5a825
Publikováno v:
Platelets, Vol 29, Iss 6, Pp 541-548 (2018)
Platelets serotonin (5-hydroxytrytamine, 5-HT) uptake and storage in dense granules is tightly regulated by the serotonergic transport system in the blood. Several 5-HT transporters (5-HTTs) have been identified in the vasculature and blood cells, be
Externí odkaz:
https://doaj.org/article/a011e7f41046496784f5db6571d3c3f0
Autor:
Simon Stritt, Inga Birkholz, Sarah Beck, Simona Sorrentino, K. Tanuj Sapra, Julien Viaud, Johannes Heck, Frédérique Gaits-Iacovoni, Harald Schulze, Xiaoping Du, John H. Hartwig, Attila Braun, Markus Bender, Ohad Medalia, Bernhard Nieswandt
Publikováno v:
Blood Advances, Vol 2, Iss 9, Pp 1040-1045 (2018)
Externí odkaz:
https://doaj.org/article/1d71a5cd9b934bc4bd3992708594c9c0
Autor:
Magdolna Nagy, Johanna P. van Geffen, David Stegner, David J. Adams, Attila Braun, Susanne M. de Witt, Margitta Elvers, Mitchell J. Geer, Marijke J. E. Kuijpers, Karl Kunzelmann, Jun Mori, Cécile Oury, Joachim Pircher, Irina Pleines, Alastair W. Poole, Yotis A. Senis, Remco Verdoold, Christian Weber, Bernhard Nieswandt, Johan W. M. Heemskerk, Constance C. F. M. J. Baaten
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Genetically modified mice are indispensable for establishing the roles of platelets in arterial thrombosis and hemostasis. Microfluidics assays using anticoagulated whole blood are commonly used as integrative proxy tests for platelet function in mic
Externí odkaz:
https://doaj.org/article/bf144e9b91d74d40b88d09d030089336