Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Atte P. Kyllönen"'
Publikováno v:
The Prostate. 62:267-274
Background The molecular mechanisms underlying the development and progression of prostate cancer have remained poorly understood. To find out potential genetic markers likely to underlie tumor progression, the pattern of allelic loss on chromosome a
Publikováno v:
Cancer. 92:2975-2984
BACKGROUND There is a need for specific markers that can indicate the different stages of prostate carcinoma. There is ongoing speculation concerning the value of prostate specific glandular kallikrein (hK2) in this regard. METHODS The expression lev
Publikováno v:
International Journal of Cancer. 94:705-710
The serine protease TMPRSS2 gene expression was studied by in situ hybridization using benign prostatic hyperplasia and prostate cancer tissue samples from 32 patients. Expression of TMPRSS2 gene was higher in cancer cells than that in benign cells i
Autor:
Olavi Lukkarinen, Atte P. Kyllönen, Markku H. Vaarala, Timo Marttila, Katja Porvari, Pirkko Vihko
Publikováno v:
World Journal of Urology. 18:406-410
This study was aimed at exploring the effect of finasteride, a non-steroidal competitive inhibitor of the enzyme 5alpha-reductase, on 5alpha-reductase type 2 at the mRNA level in human prostate, using an in situ hybridization technique. After randomi
Publikováno v:
Laboratory Investigation. 80:1259-1268
Prostate cancer tends to become transformed to androgen-independent disease over time when treated by androgen-deprivation therapy. We used two variants of the human prostate cancer cell line LNCaP to study gene expression differences during prostate
Autor:
Pirkko Vihko, Olavi Lukkarinen, Mika Mustonen, Markku H. Vaarala, Atte P. Kyllönen, Katja Porvari
Publikováno v:
International Journal of Cancer. 78:27-32
A cDNA library specific for mRNA over-expressed in prostate cancer was generated by subtractive hybridization of transcripts originating from prostatic hyperplasia and cancer tissues. cDNA encoding ribosomal proteins L4, L5, L7a, L23a, L30, L37, S14
Autor:
Pirkko Vihko, Olavi Lukkarinen, Lateef A. Akinola, Matti Poutanen, Atte P. Kyllönen, Jussi P. Elo, Reijo Vihko
Publikováno v:
International Journal of Cancer. 66:37-41
In the present study, expressions of 17beta-hydroxysteroid dehydrogenase (17HSD) types 1, 2, and 3, 5alpha-reductase type 2 and human androgen receptor mRNAs were determined in 12 benign prostatic hyperplasia and 17 prostatic carcinoma specimens. 17H
Publikováno v:
Gynecologic Oncology. 82:389-391
Background. Granulosa cell tumors are known to be hormonally active. They usually produce estrogen and inhibin, and the serum inhibin level is often considered a useful tumor marker during the follow-up of this illness. Case. We present a case of mal
Autor:
Tuomo J. Karttunen, Annikki Liakka, Karoliina Tuppurainen, Atte P. Kyllönen, Hannu Tuominen, Oili E. Junttila, Markus J. Mäkinen, Johanna M. Mäkinen
Publikováno v:
The Journal of pathology. 207(3)
Colorectal serrated adenocarcinoma originates from serrated adenoma, but definite histological criteria have not yet been established. It presents with frequent DNA microsatellite instability (MSI), but the frequency of low-level (MSI-L) and high-lev
Publikováno v:
The Prostate. 62(3)
The molecular mechanisms underlying the development and progression of prostate cancer have remained poorly understood. To find out potential genetic markers likely to underlie tumor progression, the pattern of allelic loss on chromosome arm 16q in m