Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Attan Kasid"'
Publikováno v:
Annals of the New York Academy of Sciences. 557:564-566
Autor:
Terence P. Wade, Leonard G. Gomella, Attan Kasid, Renato V. Larocca, Eric R. Sargent, Charles E. Myers, Cy A. Stein, W. Marston Linehan
Publikováno v:
Journal of Surgical Research. 53:195-198
Suramin is a polyanionic compound used clinically for the treatment of trypanosomiasis, which is known to inhibit the action of many protein factors in vitro. Transforming growth factor-beta (TGF-beta) is a multifunctional regulatory protein which in
Autor:
Principal Investigator: Steven A. Rosenberg, S. E. Ettinghausen, Patrick Hwu, David R. Parkinson, Suzanne L. Topalian, A. L. Asher, Jeffrey S. Weber, John R. Yannelli, James J. Mulé, Attan Kasid, James Chih-Hsin Yang, Douglas J. Schwartzentruber, Investigators: W. F. Anderson, M. R. Blaese, W. M. Linehan
Publikováno v:
Human Gene Therapy. 3:57-73
Autor:
Attan Kasid, Suzanne L. Topalian, Principal Investigator: Steven A. Rosenberg, S. E. Karp, Investigators: W. F. Anderson, Jeffrey S. Weber, M. R. Blaese, S. E. Ettinghausen, Patrick Hwu, John R. Yannelli, David R. Parkinson, W. M. Linehan, J. C. Salo, Douglas J. Schwartzentruber, James J. Mulé, James Chih-Hsin Yang
Publikováno v:
Human Gene Therapy. 3:75-90
Publikováno v:
Molecular Endocrinology. 5:1740-1747
We studied the effects of interleukin-1 alpha (IL-1) and tumor necrosis factor-alpha (TNF), alone and in combination, on MCF-7 breast cancer cells to determine whether these cytokines alter cell growth, TNF gene expression, and TNF secretion. We foun
Autor:
Attan Kasid, Steven A. Rosenberg, Kenneth Cornetta, Paul Aebersold, Karson E, W. French Anderson, R. Michael Blaese, Shoshana Morecki
Publikováno v:
Cancer Immunology Immunotherapy. 32:342-352
Studies were undertaken to test the susceptibility of individual T cell subpopulations to retroviral-mediated gene transduction. Gene transfer into human tumor-infiltrating lymphocytes (TIL) or peripheral blood mononuclear cells (PBMC) was carried ou
Publikováno v:
Human Gene Therapy. 1:373-384
Patients with malignant melanoma have been treated with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes (TIL) marked by retroviral gene transduction. The retroviral vector contained a gene coding for the bacterial enzyme neomycin phosphotrans
Autor:
Steven A. Rosenberg, Maria J. Merino, Michael T. Lotze, R. Michael Blaese, Paul Aebersold, Attan Kasid, Kenneth Cornetta, Richard A. Morgan, A. Dusty Miller, Kenneth W. Culver, James Chih-Hsin Yang, Suzanne L. Topalian, Robert C. Moen, Karson E, W. French Anderson
Publikováno v:
New England Journal of Medicine. 323:570-578
Treatment with tumor-infiltrating lymphocytes (TIL) plus interleukin-2 can mediate the regression of metastatic melanoma in approximately half of patients. To optimize this treatment approach and define the in vivo distribution and survival of TIL, w
Publikováno v:
Atherosclerosis. 156(1)
Human lecithin:cholesterol acyltransferase (LCAT) plays a key role in the biogenesis of circulating high-density lipoprotein-cholesterol (HDL-C) and reverse cholesterol efflux. We investigated the molecular defect in the LCAT gene in a family with lo
Autor:
Michael T. Lotze, Kenneth W. Culver, Wayne F. Anderson, Shoshana Morecki, Steven A. Rosenberg, Robert O. Morgan, Attan Kasid, Kenneth Cornetta, R M Blaese, Paul Aebersold
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 88(8)
The application of bone marrow gene therapy has been stalled by the inability to achieve stable high-level gene transfer and expression in the totipotent stem cells. We show that retroviral vectors can stably introduce genes into antigen-specific mur