Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Atsuyuki Nishida"'
Publikováno v:
Experimental Animals. 59:85-93
The present study was designed to evaluate the time-dependent effects of Nanpao, a kampo medicine, on age-related changes in the estrous cycle of female rats, and to investigate the utility of measuring electrical impedance in the vagina (EIV) for st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1582fa871c861011564be434480cda5
https://doi.org/10.1538/expanim.59.85
https://doi.org/10.1538/expanim.59.85
Autor:
Masaru Ichihashi, Yoshikatsu Hashimoto, Tatsuya Honda, Chisato Kokubun, Kazuyuki Kitamura, Aoi Matsuda, Atsuyuki Nishida, Kouji Yano
Publikováno v:
The American Journal of Chinese Medicine. 36:873-887
The improvement effect of Nanpao, a Kampo medicine, on the age-related decline in reproductive function was evaluated in female rats given the test drug for a long-term period. Young rats were allocated to the cesarean section and natural delivery gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92162e87ebac093968293f94612a4802
https://doi.org/10.1142/s0192415x08006314
https://doi.org/10.1142/s0192415x08006314
Autor:
Atsuyuki Nishida, Hiroko Satou, Naoya Masutomi, Tamiko Adachi, Hiroshi Shibata, Satoko Miwa, Yuko Satou, Yumiko Iwase, Toshinobu Yamamoto
Publikováno v:
International journal of toxicology. 34(1)
Phototoxicity has a strong impact on drug development. Although several animal models have been developed to quantitatively assess human risks, none have been validated for standardized use. In this study, we validated an in vivo phototoxicity model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e7bdf61e9bf0ee87db6ec3262c5221
https://pubmed.ncbi.nlm.nih.gov/25432946
https://pubmed.ncbi.nlm.nih.gov/25432946
Autor:
Munekazu Shigekawa, Koji Wakimoto, Sumiyo Kudoh, Hiroshi Imahie, Atsushi Yao, Osami Kohmoto, Kinji Kobayashi, Sadahiro Azuma, Kenji Omori, Issei Komuro, Makoto Kuro-o, Takahiro Iwamoto, Yo-ichi Nabeshima, Satomi Kita, Yutaka Toyoda, Noriyuki Yanaka, Yoshio Yazaki, Toru Oka, Atsuyuki Nishida, Yuji Imai
Publikováno v:
Journal of Biological Chemistry. 275:36991-36998
Ca(2+), which enters cardiac myocytes through voltage-dependent Ca(2+) channels during excitation, is extruded from myocytes primarily by the Na(+)/Ca(2+) exchanger (NCX1) during relaxation. The increase in intracellular Ca(2+) concentration in myocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8b4c07f9f278e92b64a8d0c4e59b63
https://doi.org/10.1074/jbc.m004035200
https://doi.org/10.1074/jbc.m004035200
Publikováno v:
The Journal of Toxicological Sciences. 22:395-403
Teratogenicity study of taltirelin hydrate, a thyrotropin releasing hormone analogue, was carried out in Japanese white rabbits. Female rabbits were orally given taltirelin hydrate at a dose of 0 (control), 0.15, 1.5, or 15 mg/kg from day 6 to day 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9ca765f1332e3fc238c44e8704555d
https://doi.org/10.2131/jts.22.supplementii_395
https://doi.org/10.2131/jts.22.supplementii_395
Relationship between Teratogenic Effects and Tissue Binding Pattern of Concanavalin A in Rat Embryos
Publikováno v:
Congenital Anomalies. 34:113-123
This study was conducted to examine the effects of concanavalin A (Con A) on rat neurulation. Con A was injected intravenously to pregnant rats at a single dose of 5, 10, or 20 mg/kg between gestational days (GD) 7.5 and 10.0, and the embryos were ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57ba29c566b64eda1c1c40b4bddb5fd7
https://doi.org/10.1111/j.1741-4520.1994.tb00794.x
https://doi.org/10.1111/j.1741-4520.1994.tb00794.x
Autor:
Kazuyuki Kitamura, Kouji Yano, Masaru Ichihashi, Atsuyuki Nishida, Yoshikatsu Hashimoto, Hiromi Takatani
Publikováno v:
Experimental animals. 58(1)
The effects of long-term treatment with Nanpao, a kampo medicine, on cold constitution were evaluated in aged female rats. Five-month-old rats were administered Nanpao orally at doses of 0, 30, or 100 mg/kg/day. The peripheral blood flow and surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0734f2ebe067ea1e196653ff766f6d45
https://pubmed.ncbi.nlm.nih.gov/19151515
https://pubmed.ncbi.nlm.nih.gov/19151515
Autor:
Atsuyuki Nishida, Kazuyuki Kitamura, Tomonari Nishimura, Chisato Kokubun, Mina Hasegawa, Toshihide Inui, Tatsuya Honda, Katsuya Honda
Publikováno v:
The Journal of toxicological sciences. 33(3)
The aim of this study is to report how pregnancy alters hematology and clinical chemistry values in rats. Female and male Sprague-Dawley rats were mated; the day of copulation was designated as Day 0. Hematology and clinical chemistry measurements we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9831e4be442d90602e9dbcc1a032841b
https://pubmed.ncbi.nlm.nih.gov/18670170
https://pubmed.ncbi.nlm.nih.gov/18670170
Publikováno v:
The Journal of toxicological sciences. 22
Teratogenicity study of taltirelin hydrate, a thyrotropin releasing hormone analogue, was carried out in Wistar rats. Female rats were orally given taltirelin hydrate at a dose of 0 (control), 0.15, 1.5, or 15 mg/kg from day 7 to day 17 of gestation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989db62e5109932245b6abb3b7a704b9
https://pubmed.ncbi.nlm.nih.gov/9430096
https://pubmed.ncbi.nlm.nih.gov/9430096
Publikováno v:
Teratogenesis, carcinogenesis, and mutagenesis. 17(3)
The developmental toxicity of concanavalin A (Con A) was evaluated in vitro using a rat whole embryo culture system, and the distributions of the neural crest cells were immunohistochemically investigated in embryos with monoclonal antibody HNK-1. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376e53159a9aa0481a25e4ea64e374e3
https://pubmed.ncbi.nlm.nih.gov/9436260
https://pubmed.ncbi.nlm.nih.gov/9436260