Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Atsuya Maruyama"'
Autor:
Yoshiaki Masaki, Atsuya Maruyama, Keita Yoshida, Takahito Tomori, Tomohiro Kishimura, Kohji Seio
Publikováno v:
Bioconjugate Chemistry. 33:272-278
Publikováno v:
Organic & Biomolecular Chemistry. 17:859-866
To systematically determine the effect of N2-heteroaryl modification on the stability of G-quadruplex structures, six types of N2-heteroarylated deoxyguanosines were incorporated into oligonucleotides with intramolecular quadruplex-forming sequences
Autor:
Jun Tanihata, Keishi Yamamoto, Kohji Seio, Shin'ichi Takeda, Tetsuya Nagata, Keita Yoshida, Atsuya Maruyama, Takeshi Inde, Yoshiaki Masaki, Mitsuo Sekine
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:160-163
The effect of 2'-O-(N-methylcarbamoyl)ethyl (MCE) modification on splice-switching oligonucleotides (SSO) was systematically evaluated. The incorporation of five MCE nucleotides at the 5'-termini of SSOs effectively improved the splice switching effe
Publikováno v:
The Proceedings of the Annual Convention of the Japanese Psychological Association. 82:3EV-042
Autor:
Kohji Seio, Mitsuo Sekine, Yoshiaki Masaki, Yuya Miyatake, Takahito Tomori, Yu Ito, Naoaki Makio, Takeshi Inde, Atsuya Maruyama
Publikováno v:
Organic & Biomolecular Chemistry. 15:8371-8383
To systematically understand the effect of 2-N-heteroarylguanine (GHA) modification on the stability of higher-order DNA structures, nucleoside derivatives and oligodeoxyribonucleotides containing guanine residues modified with four kinds of hereroar
Autor:
Takahito Tomori, Atsuya Maruyama, Hiroyuki Nakajima, Yusuke Iriyama, Keishi Yamamoto, Keita Yoshida, Yoshiaki Masaki, Tatsuro Kanaki, Kohji Seio
Publikováno v:
Organicbiomolecular chemistry. 17(19)
For the improvement of nuclease resistance, four kinds of new modifications through a carbamoylethyl linker were designed. Among them, the 2′-O-[2-N-{2-(benzimidazol-1-yl)ethyl}carbamoylethyl] modification showed 20-fold longer half-life when treat
Publikováno v:
Organicbiomolecular chemistry. 17(4)
To systematically determine the effect of N2-heteroaryl modification on the stability of G-quadruplex structures, six types of N2-heteroarylated deoxyguanosines were incorporated into oligonucleotides with intramolecular quadruplex-forming sequences