Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Atsutaka Masuda"'
Autor:
Toru Nakamura, Atsutaka Masuda, Makoto Kako, Hirayuki Enomoto, Masaki Kaibori, Yasuyuki Fujita, Kyoko Tanizawa, Tetsuya Ioji, Yoshihiro Fujimori, Kei Fukami, Takuma Hazama, Hideki Iwamoto, Yasukazu Kako, Kaoru Kobayashi, Hironori Koga, Koji Nagafuji, Takayasu Ohtake, Hiroyuki Suzuki, Tomoyuki Takashima, Toshitaka Tsukiyama, Haruki Uojima, Kenichi Yamahara, Koichiro Yamakado, Hidekazu Yamamoto, Kazunori Yoh, Satoshi Yoshihara, Atsuhiko Kawamoto, Shuhei Nishiguchi, Shuzo Kobayashi, Takuji Torimura, Takumi Kawaguchi
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 455-463 (2024)
Introduction: In this multicenter clinical study, we aimed to investigate the efficacy and safety of the transhepatic arterial administration of granulocyte-colony stimulating factor (G–CSF)–mobilized autologous peripheral blood (PB)-CD34+ cells
Externí odkaz:
https://doaj.org/article/b19699346ecd4bd1940b165cd426aae3
Autor:
Takahiko Sakaue, Hironori Koga, Hideki Iwamoto, Toru Nakamura, Atsutaka Masuda, Toshimitsu Tanaka, Hiroyuki Suzuki, Hideya Suga, Shingo Hirai, Toru Hisaka, Yoshiki Naito, Keisuke Ohta, Kei-ichiro Nakamura, Karuppaiyah Selvendiran, Yoshinobu Okabe, Takuji Torimura, Takumi Kawaguchi
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 6, Pp 761-772 (2024)
Background and Aims: Precise diagnostic biomarkers are urgently required for pancreatic ductal adenocarcinoma (PDAC). Therefore, the aim of this study was to identify PDAC-specific exosomal microRNAs (Ex-miRs) from pancreatic juice (PJ) and evaluate
Externí odkaz:
https://doaj.org/article/0bd6bf97ce7742739998df37a350eb8b
Autor:
Hideki Iwamoto, Hiroyuki Suzuki, Atsutaka Masuda, Takahiko Sakaue, Toru Nakamura, Toshimitsu Tanaka, Miwa Sakai, Yasuko Imamura, Hirohisa Yano, Takuji Torimura, Hironori Koga, Kaori Yasuda, Masakatsu Tsurusaki, Takahiro Seki, Takumi Kawaguchi
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108797- (2024)
Summary: Current approved anti-angiogenic drugs (AAD) for hepatocellular carcinoma (HCC) inhibit tumor angiogenesis, but affect the hepatic vasculature resulting in adverse effects. Tumor endothelial cells (TECs) differ from normal endothelial cells.
Externí odkaz:
https://doaj.org/article/031aaec1a390453d82be69fc0ff3cd30
Autor:
Hiroyuki Suzuki, Hideki Iwamoto, Takahiro Seki, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Yasuko Imamura, Takashi Niizeki, Masahito Nakano, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Miwa Sakai, Kazutoyo Morita, Masamichi Nakayama, Tomoharu Yoshizumi, Ryoko Kuromatsu, Hirohisa Yano, Yihai Cao, Hironori Koga, Takuji Torimura
Publikováno v:
Cancer Communications, Vol 43, Iss 4, Pp 415-434 (2023)
Abstract Background Antiangiogenic tyrosine kinase inhibitors (TKIs) provide one of the few therapeutic options for effective treatment of hepatocellular carcinoma (HCC). However, patients with HCC often develop resistance toward antiangiogenic TKIs,
Externí odkaz:
https://doaj.org/article/b014bbfe6ace4455a5688b7b5212c659
Autor:
Hiroyuki Suzuki, Hideki Iwamoto, Ken Yamamoto, Mai Tsukaguchi, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Takashi Niizeki, Shusuke Okamura, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Ryoko Kuromatsu, Toru Hisaka, Hirohisa Yano, Hironori Koga, Takuji Torimura
Publikováno v:
Gastro Hep Advances, Vol 1, Iss 4, Pp 555-562 (2022)
Background and Aims: Hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) progresses with a highly multicentric occurrence (MO) even after radical hepatectomy. Despite several efforts to clarify the pathogenesis of MO, the underlying molecu
Externí odkaz:
https://doaj.org/article/030a69a874c843fc9efe892d239bae68
Autor:
Hiroyuki Suzuki, Hideki Iwamoto, Masahito Nakano, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Dan Nakano, Ryoko Kuromatsu, Takashi Niizeki, Shusuke Okamura, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Hirohisa Yano, Atsushi Kawaguchi, Hironori Koga, Takuji Torimura
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101201- (2021)
Objective: Although sorafenib, a molecular targeted agent, has survival benefits for advanced hepatocellular carcinoma (HCC) patients, its disease control rate remains limited. To explore the potential for augmenting its antitumor effect, we assessed
Externí odkaz:
https://doaj.org/article/693f8ec225684fd0ac15143ba6a50f1b
Ex vivo expansion of circulating CD34+ cells enhances the regenerative effect on rat liver cirrhosis
Autor:
Toru Nakamura, Hironori Koga, Hideki Iwamoto, Victor Tsutsumi, Yasuko Imamura, Masako Naitou, Atsutaka Masuda, Yu Ikezono, Mitsuhiko Abe, Fumitaka Wada, Takahiko Sakaue, Takato Ueno, Masaaki Ii, Cantas Alev, Atsuhiko Kawamoto, Takayuki Asahara, Takuji Torimura
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Ex vivo expansion of autologous cells is indispensable for cell transplantation therapy of patients with liver cirrhosis. The aim of this study was to investigate the efficacy of human ex vivo-expanded CD34+ cells for treatment of cirrhotic rat liver
Externí odkaz:
https://doaj.org/article/ba8dfbdb893c47a8b0a8c5883ae2f795
Autor:
Hideki Iwamoto, Toru Nakamura, Hironori Koga, Jesus Izaguirre-Carbonell, Shinji Kamisuki, Fumio Sugawara, Mitsuhiko Abe, Kazuki Iwabata, Yu Ikezono, Takahiko Sakaue, Atsutaka Masuda, Hirohisa Yano, Keisuke Ohta, Masahito Nakano, Shigeo Shimose, Tomotake Shirono, Takuji Torimura
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
âAngiogenic switch offâ is one of the ideal therapeutic concepts in the treatment of cancer. However, the specific molecules which can induce âangiogenic switch offâ in tumor have not been identified yet. In this study, we focused on von Hippel-L
Externí odkaz:
https://doaj.org/article/7639fc3321b84cceb509d4cc4306cfb7
Autor:
Takuji Torimura, Osamu Tsuruta, Hirohisa Yano, Takahiko Sakaue, Atsutaka Masuda, Hideki Iwamoto, Toru Nakamura, Fumitaka Wada, Takafumi Yoshida, Mitsuhiko Abe, Jun Akiba, Hironori Koga, Yu Ikezono
Sphere formation assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d890a4ddc820196b9abe61854a759c
https://doi.org/10.1158/1541-7786.22511088
https://doi.org/10.1158/1541-7786.22511088
Autor:
Takuji Torimura, Osamu Tsuruta, Hirohisa Yano, Takahiko Sakaue, Atsutaka Masuda, Hideki Iwamoto, Toru Nakamura, Fumitaka Wada, Takafumi Yoshida, Mitsuhiko Abe, Jun Akiba, Hironori Koga, Yu Ikezono
Expression of DCLK1 in primary liver NET (LNET) tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c36389c7e9d1680c7056632b774d229
https://doi.org/10.1158/1541-7786.22511094.v1
https://doi.org/10.1158/1541-7786.22511094.v1