Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Atsushi Sanbe"'
Autor:
Toshihiro Yamaguchi, Tomokazu S. Sumida, Seitaro Nomura, Masahiro Satoh, Tomoaki Higo, Masamichi Ito, Toshiyuki Ko, Kanna Fujita, Mary E. Sweet, Atsushi Sanbe, Kenji Yoshimi, Ichiro Manabe, Toshikuni Sasaoka, Matthew R. G. Taylor, Haruhiro Toko, Eiki Takimoto, Atsuhiko T. Naito, Issei Komuro
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
The pathophysiological role of dopamine D1 receptor (D1R) in chronic heart failure remains elusive. Here the authors show that D1R-expressing cardiomyocytes appear in chronic heart failure and play a pivotal role in triggering lethal ventricular arrh
Externí odkaz:
https://doaj.org/article/59249ab8e1b144e4814231c3afc24f46
Autor:
Nanae Ishida, Maki Saito, Sachiko Sato, Yu Tezuka, Atsushi Sanbe, Eiichi Taira, Masamichi Hirose
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Previously, we showed that sodium/glucose cotransporter 1 (SGLT1) participates in vascular cognitive impairment in small vessel disease. We hypothesized that SGLT1 inhibitors can improve the small vessel disease induced‐vascular cognitive
Externí odkaz:
https://doaj.org/article/1e0e990177ba4dcf88705313dbc2b738
Autor:
Naoko Matsushita, Toshihide Kashihara, Hisashi Shimojo, Satoshi Suzuki, Tsutomu Nakada, Yasuchika Takeishi, Ulrike Mende, Eiichi Taira, Mitsuhiko Yamada, Atsushi Sanbe, Masamichi Hirose
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106354 (2014)
Transgenic mice with transient cardiac expression of constitutively active Galpha q (Gαq-TG) exhibt progressive heart failure and ventricular arrhythmias after the initiating stimulus of transfected constitutively active Gαq becomes undetectable. H
Externí odkaz:
https://doaj.org/article/645fbbeae7b649299460c15e1a616d18
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61649 (2013)
Neural cell differentiation during development is controlled by multiple signaling pathways, in which protein phosphorylation and dephosphorylation play an important role. In this study, we examined the role of pyrophosphatase1 (PPA1) in neuronal dif
Externí odkaz:
https://doaj.org/article/7ae8df823aa643f89ccb0aad6a6fb03b
Autor:
Atsushi Sanbe, Tetsuro Marunouchi, Junji Yamauchi, Kouichi Tanonaka, Hideo Nishigori, Akito Tanoue
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18922 (2011)
BACKGROUND: Transgenic (TG) mice with overexpression of an arg120gly (R120G) missense mutation in HSPB5 display desmin-related cardiomyopathy, which is characterized by formation of aggresomes. It is also known that progressive mitochondrial abnormal
Externí odkaz:
https://doaj.org/article/18ab49b99d904440874969a71f016b2e
Autor:
Atsushi Sanbe, Takuya Daicho, Reiko Mizutani, Toshiya Endo, Noriko Miyauchi, Junji Yamauchi, Kouichi Tanonaka, Charles Glabe, Akito Tanoue
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5351 (2009)
An arg120gly (R120G) missense mutation in HSPB5 (alpha-beta-crystallin ), which belongs to the small heat shock protein (HSP) family, causes desmin-related cardiomyopathy (DRM), a muscle disease that is characterized by the formation of inclusion bod
Externí odkaz:
https://doaj.org/article/05d3b98d87f64f76914b3d7a48cebbc2
Autor:
Atsushi, Sanbe, Yui, Inomata, Naoko, Matsushita, Yohei, Sawa, Chizuru, Hino, Hinano, Yamazaki, Kei, Takanohashi, Natsuko, Takahashi, Rieko, Higashio, Hideki, Tsumura, Toshinori, Aoyagi, Masamichi, Hirose
Publikováno v:
Biochemical and Biophysical Research Communications. 631:48-54
Histone deacetylase 6 (HDAC6) is known to deacetylate amino acid lysine in alpha-tubulin. However, the functional role of HDAC6 in the progression of cardiac disease remains uncertain. The functional role of HDAC6 in the hearts was examined using tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf96136e55d3ae08defbe82243b1ae4
https://doi.org/10.1016/j.bbrc.2022.09.055
https://doi.org/10.1016/j.bbrc.2022.09.055
Autor:
Masamichi Ito, Toshikuni Sasaoka, Eiki Takimoto, Ichiro Manabe, Tomoaki Higo, Tomokazu Sumida, Toshiyuki Ko, Haruhiro Toko, Matthew R.G. Taylor, Atsushi Sanbe, Mary E. Sweet, Masahiro Satoh, Atsuhiko T. Naito, Seitaro Nomura, Issei Komuro, Kanna Fujita, Toshihiro Yamaguchi, Kenji Yoshimi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications
Nature Communications
Pathophysiological roles of cardiac dopamine system remain unknown. Here, we show the role of dopamine D1 receptor (D1R)-expressing cardiomyocytes (CMs) in triggering heart failure-associated ventricular arrhythmia. Comprehensive single-cell resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58215becc3d0eb17337ed61be34b0d2c
https://doaj.org/article/59249ab8e1b144e4814231c3afc24f46
https://doaj.org/article/59249ab8e1b144e4814231c3afc24f46
Autor:
Daijiro Kurosaka, Daisuke Sakai, Kazuhiro Fukuda, Umi Tanaka, Atsushi Sanbe, Toshiyasu Imaizumi
Publikováno v:
Experimental Eye Research. 181:145-149
The deposition of extracellular matrix (ECM)-which is mainly composed of type I collagen-in anterior subcapsular cataracts (ASCs) during epithelial-to-mesenchymal transition (EMT) of lens epithelial cells (LECs) decreases visual function. Transformin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3972bd69efa8267303faf55e78e8e7b0
https://doi.org/10.1016/j.exer.2019.01.016
https://doi.org/10.1016/j.exer.2019.01.016
Autor:
Atsushi Sanbe, Yui Inomata, Shintaro Takahashi, Sachi Tamada, Youko Natsubori, Rieko Higashio
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:4-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b420e068fa7a173bf721077a4491280
https://doi.org/10.1254/jpssuppl.96.0_4-b-p-267
https://doi.org/10.1254/jpssuppl.96.0_4-b-p-267