Zobrazeno 1 - 10
of 607
pro vyhledávání: '"Atsushi SUGIYAMA"'
Autor:
Makoto Miura, Atsushi Sugiyama, Yoshinobu Oshikiri, Ryoichi Morimoto, Iwao Mogi, Miki Miura, Yusuke Yamauchi, Ryoichi Aogaki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Through a copper double bipolar magnetohydrodynamic (MHD) electrode (MHDE) producing twice the amounts of ionic vacancies than a conventional single MHDE, the molar excess heat of the pair annihilation of ionic vacancies, 702 kJ mol−1 at 1
Externí odkaz:
https://doaj.org/article/ff3e8870ff874c19945504547d0dc9cc
Autor:
Ai Goto, Ryuichi Kambayashi, Hiroko Izumi-Nakaseko, Makoto Shinozaki, Yoshinori Takei, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 4, Pp 201-209 (2023)
We simultaneously assessed electropharmacological effects of anti-atrial fibrillatory drug vernakalant and its potential risk toward torsade de pointes. Vernakalant hydrochloride in doses of 0.3 and 3 mg/kg/10 min was intravenously administered to is
Externí odkaz:
https://doaj.org/article/b956d5c03fd84d6aa6002752932fa2bc
Autor:
Misa Kimura, Yoichi Sakurada, Yoshiko Fukuda, Mio Matsubara, Yumi Kotoda, Yuka Kasai, Atsushi Sugiyama, Wataru Kikushima, Daphne Viel Tsuru, Kenji Kashiwagi
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 687 (2024)
Purpose: We compared 12-month outcomes of eyes with polypoidal choroidal vasculopathy (PCV) with or without complete regression of polyps observed one month after three monthly intravitreal administrations (loading phase) of aflibercept (2.0 mg/0.05
Externí odkaz:
https://doaj.org/article/42563a0195374928b27c42ffc46960ec
Autor:
Ryoichi Morimoto, Miki Miura, Atsushi Sugiyama, Makoto Miura, Yoshinobu Oshikiri, Iwao Mogi, Yusuke Yamauchi, Ryoichi Aogaki
Publikováno v:
Magnetochemistry, Vol 10, Iss 4, p 25 (2024)
The contributions of magnetohydrodynamic (MHD) vortexes to chiral electrodeposition in a vertical magnetic field were theoretically examined based on the three-generation model of the 2D nucleus, 3D nucleus, and screw dislocation; for the vortexes to
Externí odkaz:
https://doaj.org/article/699e3e6c4dcc4efa9be0a154d58ad2f6
Autor:
Wataru Kikushima, Yoichi Sakurada, Atsushi Sugiyama, Seigo Yoneyama, Mio Matsubara, Yoshiko Fukuda, Taiyo Shijo, Yumi Kotoda, Serena Fragiotta, Kenji Kashiwagi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Hyperreflective foci (HRF) are the findings observed in optical coherence tomography (OCT) in several retinal diseases and are believed to be associated with the increased risk of atrophy in eyes with age-related macular degeneration (AMD).
Externí odkaz:
https://doaj.org/article/19ca26257fdd426dba9c83b79b3994b1
Autor:
Ryuichi Kambayashi, Ai Goto, Hiroko Izumi-Nakaseko, Ichiro Oikawa, Naoki Ikeda, Kazuki Matsuda, Yoshinori Takei, Akio Matsumoto, Yuji Kumagai, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 3, Pp 191-199 (2022)
We investigated how a lack of placebo control affects the interpretation of results of thorough QT/QTc (TQT) study. Results of TQT study in 48 healthy Japanese subjects assessing the effects of 480 and 960 mg of carotegrast methyl (test drug) and 400
Externí odkaz:
https://doaj.org/article/f7331423d2d34f96a3ee8982550b8a7f
Autor:
Koki Chiba, Ryuichi Kambayashi, Mayu Onozato, Ai Goto, Hiroko Izumi-Nakaseko, Yoshinori Takei, Akio Matsumoto, Koichiro Tanaka, Yasunari Kanda, Takeshi Fukushima, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 3, Pp 154-162 (2022)
Imatinib has been reported to induce heart failure and/or QTc prolongation. To better understand their underlying mechanisms, we assessed its effects on cardiohemodynamic, electrocardiographic and echocardiographic variables along with biomarkers of
Externí odkaz:
https://doaj.org/article/fd87e9c0826943c79c0ee21cfceafe87
Autor:
Aneesh V. Karkhanis, Gopalakrishnan Venkatesan, Ryuichi Kambayashi, Jacqueline Wen Hui Leow, Marcus Qingrui Han, Hiroko Izumi-Nakaseko, Ai Goto, Jeremy Kah Sheng Pang, Boon Seng Soh, Pipin Kojodjojo, Atsushi Sugiyama, Eric Chun Yong Chan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 10, Pp 3905-3923 (2022)
Cytochrome P4502J2 (CYP2J2) metabolizes arachidonic acid (AA) to cardioprotective epoxyeicosatrienoic acids (EETs). Dronedarone, an antiarrhythmic drug prescribed for treatment of atrial fibrillation (AF) induces cardiac adverse effects (AEs) with po
Externí odkaz:
https://doaj.org/article/e6843c2c6f2348c9b79633b11dd4d46d
Autor:
Ryuichi Kambayashi, Ai Goto, Hiroko Izumi-Nakaseko, Yoshinori Takei, Akio Matsumoto, Shinichi Kawai, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 4, Pp 175-178 (2022)
Since information is still limited whether atrial IK,ACh may become a potential therapeutic target to terminate persistent atrial fibrillation (AF), we assessed it by using the persistent AF canine model with representative IK,ACh inhibitor AVE0118 a
Externí odkaz:
https://doaj.org/article/fe14cffa9ba44d31a53fd6e227c8f262
Autor:
Seigo Yoneyama, Ayumi Fukui, Yoichi Sakurada, Nobuhiro Terao, Taiyo Shijo, Natsuki Kusada, Atsushi Sugiyama, Mio Matsubara, Yoshiko Fukuda, Wataru Kikushima, Ravi Parikh, Fumihiko Mabuchi, Chie Sotozono, Kenji Kashiwagi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract To investigate the differences in clinical and genetic characteristics between males and females with central serous chorioretinopathy (CSC). Consecutive 302 patients (mean age; 56.3 ± 11.7, male/female: 249/53) with CSC were evaluated on t
Externí odkaz:
https://doaj.org/article/bfb0dde9f3ca4978a018dc892df7314c