Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Atsushi Okabe"'
Autor:
Harue Mizokami, Atsushi Okabe, Ruchi Choudhary, Masato Mima, Kenta Saeda, Masaki Fukuyo, Bahityar Rahmutulla, Motoaki Seki, Boon-Cher Goh, Satoru Kondo, Hirotomo Dochi, Makiko Moriyama-Kita, Kiyoshi Misawa, Toyoyuki Hanazawa, Patrick Tan, Tomokazu Yoshizaki, Melissa Jane Fullwood, Atsushi Kaneda
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105057- (2024)
Summary: Background: Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignant epithelial tumor endemic to Southern China and Southeast Asia. While previous studies have revealed a low frequency of gene mutations in NPC, its
Externí odkaz:
https://doaj.org/article/0d406c389ac048dea04ff8c3811564af
Autor:
Kouichi Kitamura, Tyuji Hoshino, Atsushi Okabe, Masaki Fukuyo, Bahityar Rahmutulla, Nobuko Tanaka, Sohei Kobayashi, Tomoaki Tanaka, Takashi Shida, Mashiro Ueda, Toshinari Minamoto, Hisahiro Matsubara, Atsushi Kaneda, Hideshi Ishii, Kazuyuki Matsushita
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17341 (2023)
The interaction between mRNA and ribosomal RNA (rRNA) transcription in cancer remains unclear. RNAP I and II possess a common N-terminal tail (NTT), RNA polymerase subunit RPB6, which interacts with P62 of transcription factor (TF) IIH, and is a comm
Externí odkaz:
https://doaj.org/article/a0cff5f04aac422ea084b85f427bed9b
Autor:
Khine Myint, Linda Shyue Huey Chuang, Yu Xuan Teh, Nur Astiana Mawan, Edward Jizhong Shi, Michelle Meng Huang Mok, Napat Nuttonmanit, Junichi Matsuo, Ying Li, Henry Yang, Atsushi Okabe, Atsushi Kaneda, Motomi Osato, Jimmy Bok-Yan So, Wei Peng Yong, Patrick Tan, Khay Guan Yeoh, Yoshiaki Ito
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105194- (2022)
Summary: We reported earlier that IQGAP3 is an important stem cell factor in rapidly proliferating isthmus stem cells in the stomach and that IQGAP3 expression is robustly induced in terminally differentiated chief cells and de-differentiated cells f
Externí odkaz:
https://doaj.org/article/75ca2ac94f5b4c3b9d3f7a5561031c57
Autor:
Masahiro Sugiura, Hiroaki Sato, Atsushi Okabe, Masaki Fukuyo, Yasunobu Mano, Ken-ichi Shinohara, Bahityar Rahmutulla, Kosuke Higuchi, Maihulan Maimaiti, Manato Kanesaka, Yusuke Imamura, Tomomi Furihata, Shinichi Sakamoto, Akira Komiya, Naohiko Anzai, Yoshikatsu Kanai, Jun Luo, Tomohiko Ichikawa, Atsushi Kaneda
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100915- (2021)
Primary prostate cancer (PC) progresses to castration-resistant PC (CRPC) under androgen deprivation therapy, by mechanisms e.g. expression of androgen receptor (AR) splice variant-7 (AR-V7). Here we conducted comprehensive epigenome and transcriptom
Externí odkaz:
https://doaj.org/article/671acd9b19694fd9a7b26391bbb6ca70
Autor:
Atsushi Okabe, Sayaka Funata, Keisuke Matsusaka, Hiroe Namba, Masaki Fukuyo, Bahityar Rahmutulla, Motohiko Oshima, Atsushi Iwama, Masashi Fukayama, Atsushi Kaneda
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Epstein-Barr virus (EBV) infection is associated with tumours such as Burkitt lymphoma, nasopharyngeal carcinoma, and gastric cancer. We previously showed that EBV(+) gastric cancer presents an extremely high-methylation epigenotype and this
Externí odkaz:
https://doaj.org/article/259f6969d1784586ba7b0a61a019ae80
Autor:
Yoshikazu Johmura, Jia Sun, Kyoko Kitagawa, Keiko Nakanishi, Toshiya Kuno, Aya Naiki-Ito, Yumi Sawada, Tomomi Miyamoto, Atsushi Okabe, Hiroyuki Aburatani, ShengFan Li, Ichiro Miyoshi, Satoru Takahashi, Masatoshi Kitagawa, Makoto Nakanishi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Cellular senescence—the permanent cessation of cell proliferation—is a process that can be deregulated in cancer and other aging-related diseases. Here the authors demonstrate that the SCFFbxo22-KDM4A complex plays an essential role during senesc
Externí odkaz:
https://doaj.org/article/a78817db806f42beac081b69b8dcfa12
Autor:
Takashi Kumagai, Arifumi Iwata, Hiroki Furuya, Kodai Kato, Atsushi Okabe, Yosuke Toda, Mizuki Kanai, Lisa Fujimura, Akemi Sakamoto, Takahiro Kageyama, Shigeru Tanaka, Akira Suto, Masahiko Hatano, Atsushi Kaneda, Hiroshi Nakajima
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/2/2024, Vol. 121 Issue 27, p1-9, 22p
Autor:
Masato Mima, Atsushi Okabe, Takayuki Hoshii, Takuya Nakagawa, Tomoya Kurokawa, Satoru Kondo, Harue Mizokami, Masaki Fukuyo, Ryoji Fujiki, Bahityar Rahmutulla, Tomokazu Yoshizaki, Toyoyuki Hanazawa, Kiyoshi Misawa, Atsushi Kaneda
Publikováno v:
International Journal of Cancer. 152:1847-1862
Autor:
Takuya Hasegawa, Takatoshi Araki, Atsushi Okabe, Yusuke Kato, Atsushi Ooshiro, Sho Miyazaki, Hiroshi Kawaide, Masahiro Natsume
Publikováno v:
Journal of General Plant Pathology. 89:91-99
Autor:
Amrita M. Nargund, Chang Xu, Amit Mandoli, Atsushi Okabe, Gao Bin Chen, Kie Kyon Huang, Taotao Sheng, Xiaosai Yao, Jia Ming Nickolas Teo, Raghav Sundar, Yee Jiun Kok, Yi Xiang See, Manjie Xing, Zhimei Li, Chern Han Yong, Aparna Anand, Zul Fazreen Bin Adam Isa, Lai Fong Poon, Michelle Shu Wen Ng, Javier Yu Peng Koh, Wen Fong Ooi, Su Ting Tay, Xuewen Ong, Angie Lay Keng Tan, Duane T. Smoot, Hassan Ashktorab, Heike I. Grabsch, Melissa J. Fullwood, Bin Tean Teh, Xuezhi Bi, Atsushi Kaneda, Shang Li, Patrick Tan
Publikováno v:
Cancer Research, 82(14), 2538-2551. American Association for Cancer Research Inc.
Mutations in the DNA mismatch repair gene MSH2 are causative of microsatellite instability (MSI) in multiple cancers. Here, we discovered that besides its well-established role in DNA repair, MSH2 exerts a novel epigenomic function in gastric cancer.