Zobrazeno 1 - 10 of 102 pro vyhledávání: '"Atsushi Kurihara"'
1
Akademický článek
Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human UGT2 enzymes
Autor: Kaoru Kobayashi, Tsuneo Deguchi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Kazuomi Nakamura, Atsushi Kurihara, Mitsuo Oshimura, Yasuhiro Kazuki
Publikováno v: Pharmacology Research & Perspectives, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract UDP‐glucuronosyltransferases (UGTs) catalyze the conjugation of various substrates with sugars. Since the UGT2 family forms a large cluster spanning 1.5 Mb, transgenic mouse lines carrying the entire human UGT2 family have not been constru
Externí odkaz: https://doaj.org/article/8792878571ce483887e7d51d35ed617c
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2
Akademický článek
The Relative Association of Collective Efficacy in School and Neighborhood Contexts With Adolescent Alcohol Use
Autor: Minoru Takakura, Masaya Miyagi, Masaru Ueji, Minoru Kobayashi, Atsushi Kurihara, Akira Kyan
Publikováno v: Journal of Epidemiology, Vol 29, Iss 10, Pp 384-390 (2019)
Background: It is unclear whether either neighborhood collective efficacy or school collective efficacy is associated with adolescent alcohol use. This study aimed to examine the relative contributions of collective efficacy, both in school and in th
Externí odkaz: https://doaj.org/article/7b7529e7451043778a38ecbd595a3004
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3
Akademický článek
Excitation and Circular Dichroism Spectra of (+)-(S,S)-bis(2-Methylbutyl)chalcogenides
Autor: Yasushi Honda, Atsushi Kurihara, Yusuke Kenmochi, Masahiko Hada
Publikováno v: Molecules, Vol 15, Iss 4, Pp 2357-2373 (2010)
Theoretical electronic spectra and natural circular dichroism (CD) spectra of (+)-(S,S)-bis(2-methylbutyl)chalcogenides, Ch[CH2CH(CH3)C2H5]2 (Ch = S, Se, and Te), were calculated by the symmetry adapted cluster (SAC) and SAC-configuration interaction
Externí odkaz: https://doaj.org/article/ed3dd93dde7f400495346ff673e9414e
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4
Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human UGT2 enzymes
Autor: Kaoru Kobayashi, Tsuneo Deguchi, Satoshi Abe, Naoyo Kajitani, Kanako Kazuki, Shoko Takehara, Kazuomi Nakamura, Atsushi Kurihara, Mitsuo Oshimura, Yasuhiro Kazuki
Publikováno v: Pharmacology Research & Perspectives. 10
UDP-glucuronosyltransferases (UGTs) catalyze the conjugation of various substrates with sugars. Since the UGT2 family forms a large cluster spanning 1.5 Mb, transgenic mouse lines carrying the entire human UGT2 family have not been constructed becaus
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1a94cdfe2bedd50f63d35afa44f622
https://doi.org/10.1002/prp2.1030
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5
The Relative Association of Collective Efficacy in School and Neighborhood Contexts With Adolescent Alcohol Use
Autor: Masaru Ueji, Akira Kyan, Atsushi Kurihara, Minoru Takakura, Minoru Kobayashi, Masaya Miyagi
Publikováno v: Journal of Epidemiology, Vol 29, Iss 10, Pp 384-390 (2019)
Journal of Epidemiology
Background It is unclear whether either neighborhood collective efficacy or school collective efficacy is associated with adolescent alcohol use. This study aimed to examine the relative contributions of collective efficacy, both in school and in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0621138a4bda8c218de50fe88f3a15
https://doi.org/10.2188/jea.je20180125
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6
Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism
Autor: Minori Osamura, Mitsuo Oshimura, Mari Hashimoto, Masato Takiguchi, Kanako Kazuki, Rika Hirashima, Naoto Senda, Nico Scheer, Daisuke Satoh, Takehito Kaneko, Yasuko Tsukazaki, Jiro Kuze, Naoyo Kajitani, Shoko Takehara, Yasuhiro Kazuki, Tsuneo Deguchi, Takashi Yamamoto, Tetsushi Sakuma, Riko Wakatsuki, Ryoichi Fujiwara, Satoshi Abe, Tomoji Mashimo, Kaoru Kobayashi, Masumi Hirabayashi, Atsushi Kurihara
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Significance Genomically humanized animals overcoming species differences are invaluable for biomedical research. Although rats would be preferred over mice for several applications, generation of a humanized model is restricted to mice due to the di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a6abe0e80c40a0d93fc48413bfcd08
https://pubmed.ncbi.nlm.nih.gov/30718425
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7
Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin
Autor: Hidetaka Sakurai, Ryoko Sawamura, Takashi Izumi, Atsushi Kurihara, Naoya Wada, Akira Shinagawa, Miho Kazui, Tomoyo Honda, Yumi Nishiya
Publikováno v: Biopharmaceutics & Drug Disposition. 36:352-363
Loxoprofen (LX) is a prodrug-type non-steroidal anti-inflammatory drug which is used not only as an oral drug but also as a transdermal formulation. As a pharmacologically active metabolite, the trans-alcohol form of LX (trans-OH form) is generated a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21a98f4aae8e1db8b7b5594ffbeb8733
https://doi.org/10.1002/bdd.1945
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9
Design and implementation of system for exploring subject headings
Autor: Zhenguo Tang, Atsushi Kurihara, Harumi Murakami
Publikováno v: ASIST
Subject headings are tools for subject searches in libraries. Visualization tools for subject headings are available for such public searches as NDLSH and LCSH. We report two questionnaire investigations on how to display subject headings and their r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f898a2dee2c051516471639ad1ceda4
https://doi.org/10.1002/pra2.2015.145052010086
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