Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Atsushi Kosugi"'
Autor:
Atsushi Kosugi, Kok Hoong Leong, Eri Urata, Yoshihiro Hayashi, Shungo Kumada, Kotaro Okada, Yoshinori Onuki
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 886 (2020)
This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability of the resulting tablets. After preparing the model tablets with different values of hardness, they were stored at 25
Externí odkaz:
https://doaj.org/article/43c839b681b249fc81fbe6aab70708ef
Autor:
Yoshihiro Hayashi, Kaede Shirotori, Atsushi Kosugi, Shungo Kumada, Kok Hoong Leong, Kotaro Okada, Yoshinori Onuki
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 601 (2020)
We previously reported a novel method for the precise prediction of tablet properties (e.g., tensile strength (TS)) using a small number of experimental data. The key technique of this method is to compensate for the lack of experimental data by usin
Externí odkaz:
https://doaj.org/article/6baa12300c644da5bab24c1b6d66a181
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 80, Iss 810, Pp FE0023-FE0023 (2014)
Particle diffusion from a continuous point source was experimentally investigated to clarify the mechanism of turbulent diffusion for a wide range of turbulent Reynolds number Rλ. The values of Rλ were systematically changed from 43 to 445 by contr
Externí odkaz:
https://doaj.org/article/becb61e9ee764ab5aa6571342a991ead
Autor:
Hinako Tsuji, Shungo Kumada, Yoshihiro Hayashi, Kok Hoong Leong, Yoshinori Onuki, Atsushi Kosugi, Kotaro Okada
Publikováno v:
Journal of Pharmaceutical Sciences. 109:2585-2593
The purpose of this study was to accumulate enhanced technical knowledge about the powder properties of direct compaction grades of mannitol that could lead to new tablet formulations. Fifteen different commercial direct compaction grades of mannitol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4f59eace663dbc764a10064395bbe0
https://doi.org/10.1016/j.xphs.2020.05.010
https://doi.org/10.1016/j.xphs.2020.05.010
Autor:
Shungo Kumada, Atsushi Kosugi, Daijiro Hirai, Kotaro Okada, Yoshihiro Hayashi, Yoshinori Onuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:580-586
The aim of this study was to demonstrate the usefulness of T2 measurements conducted with a time-domain NMR (TD-NMR) for the characterization of active pharmaceutical ingredients (APIs) containing solid dosage forms. A solid dispersion (SD) and a phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcbf19df77b01b94563d19b3be7fb910
https://doi.org/10.1248/cpb.c19-00163
https://doi.org/10.1248/cpb.c19-00163
Autor:
Atsushi Kosugi, Shungo Kumada, Yoshinori Onuki, Yoshihiro Hayashi, Kotaro Okada, Daijiro Hirai
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:265-270
The aim of this study was to demonstrate the usefulness of the time-domain NMR (TD-NMR) method to characterize the crystalline state of active pharmaceutical ingredients (APIs) containing a solid dispersion. In this study, indomethacin (IMC) was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45dd5d0e3d2b8df429cedd0fc2126992
https://doi.org/10.1248/cpb.c18-00887
https://doi.org/10.1248/cpb.c18-00887
Autor:
Atsushi Kosugi, Kotaro Okada, Yoshihiro Hayashi, Kok Hoong Leong, Shungo Kumada, Yoshinori Onuki, Terushi Ito, Daijiro Hirai
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:271-276
The different states of water incorporated in wet granules were studied by a low-field benchtop 1H-NMR time-domain NMR (TD-NMR) instrument. Wet granules consisting different fillers [cornstarch (CS), microcrystalline cellulose (MCC), and D-mannitol (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06866f7183b3d659c0bce005c3cc6205
https://doi.org/10.1248/cpb.c18-00888
https://doi.org/10.1248/cpb.c18-00888
Autor:
Atsushi Kosugi, Yoshihiro Hayashi, Shungo Kumada, Daijiro Hirai, Yoshinori Onuki, Kotaro Okada
Publikováno v:
Journal of Pharmaceutical Sciences. 108:451-456
The aim of this study was to demonstrate the usefulness of the time domain nuclear magnetic resonance (TD-NMR) method to characterize the crystalline state of active pharmaceutical ingredients (APIs) containing solid dosage forms. In this study, carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dd5463ee670eaddfe8c6b06e89bdb03
https://doi.org/10.1016/j.xphs.2018.09.023
https://doi.org/10.1016/j.xphs.2018.09.023
Autor:
Kotaro Okada, Shungo Kumada, Yoshihiro Hayashi, Kok Hoong Leong, Atsushi Kosugi, Eri Urata, Yoshinori Onuki
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 12, Iss 886, p 886 (2020)
Volume 12
Issue 9
Pharmaceutics, Vol 12, Iss 886, p 886 (2020)
Volume 12
Issue 9
This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability of the resulting tablets. After preparing the model tablets with different values of hardness, they were stored at 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680b7376117a25859b821b9798a153ff
http://europepmc.org/articles/PMC7559487
http://europepmc.org/articles/PMC7559487
Autor:
Kaede Shirotori, Kotaro Okada, Kok Hoong Leong, Yoshinori Onuki, Yoshihiro Hayashi, Shungo Kumada, Atsushi Kosugi
Publikováno v:
Pharmaceutics
Volume 12
Issue 7
Pharmaceutics, Vol 12, Iss 601, p 601 (2020)
Volume 12
Issue 7
Pharmaceutics, Vol 12, Iss 601, p 601 (2020)
We previously reported a novel method for the precise prediction of tablet properties (e.g., tensile strength (TS)) using a small number of experimental data. The key technique of this method is to compensate for the lack of experimental data by usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcda36da61b4dd01954ffc6f57ba9329