Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Atsushi Kosaki"'
Autor:
Yasukiyo Mori, Noriko Kishimoto, Masato Nishimura, Noboru Maki, Hiroshi Kado, Kumiko Iida, Eiko Matsuoka, Ryo Ishida, Noriyuki Iwamoto, Tsuguru Hatta, Hiroaki Matsubara, Toshihiko Ono, Keiichi Tamagaki, Atsushi Kosaki, Yayoi Shiotsu
Publikováno v:
Nephron Extra, Vol 1, Iss 1, Pp 242-250 (2011)
Nephron Extra
Nephron Extra
Background: S100A12 is an endogenous ligand of the receptor for advanced glycation end products (RAGE). Plasma S100A12 levels are high in end-stage renal disease (ESRD) patients undergoing maintenance hemodialysis (HD). Peripheral arterial disease (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af014c5cca308b6bc2a7ba3f6ccd9f3
http://www.karger.com/Article/FullText/335198
http://www.karger.com/Article/FullText/335198
Autor:
Hiromi Jo, Atsushi Kosaki, Kei Yoshioka, Takayuki Shimazu, Hajime Otani, Masanori Fujita, Toru Okazaki, Toshiji Iwasaka, Fusakazu Jo
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 38:485-493
1. Uncoupling of nitric oxide synthase (NOS) has been implicated in the pathogenesis of left ventricular (LV) dysfunction in diabetes mellitus. In the present study, we investigated the role of NOS uncoupling in oxidative/nitrosative stress and LV dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a67df7c35d2f54a376c66bdbfcfa7d
https://doi.org/10.1111/j.1440-1681.2011.05535.x
https://doi.org/10.1111/j.1440-1681.2011.05535.x
Autor:
Toshiji Iwasaka, Hiroko Inoue, Masayoshi Fukui, Yasuaki Kijima, Yoko Uchiyama-Tanaka, Toshiko Tokoro, Takashi Hayakawa, Yasukiyo Mori, Atsushi Kosaki, Takahiro Imada, Osamu Iba, Yasunobu Shibasaki, Norihiko Sakamoto, Fumitaka Nakajima, Hiroya Masaki, Hideki Yamahara, Noriko Kishimoto, Masayuki Nagahara, Mitsushige Nishikawa
Publikováno v:
Nihon Toseki Igakkai Zasshi. 38:273-278
透析医療における治療技術が確立した現在でも, 透析患者の難治性愁訴は少なくなく, その原因として種々の炎症性サイトカイン変動との関連が示唆されている. 一方, 近年漢方処方を始
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1234329ee0643cc250fe4f751a592b10
https://doi.org/10.4009/jsdt.38.273
https://doi.org/10.4009/jsdt.38.273
Autor:
Jiro Hitomi, Toshiji Iwasaka, Takamasa Hasegawa, Megumi Inoue-Shibata, Mitsushige Nishikawa, Mitsuhiko Okigaki, Tatsuji Kimura, Kumiko Iida, Nagaoki Toyoda, Hiroya Masaki, Atsushi Kosaki, Yasukiyo Mori, Hiroaki Matsubara
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 89:5423-5428
S100A12, also called EN-RAGE (extracellular newly identified receptor for advanced glycation end products binding protein) or calcium-binding protein in amniotic fluid-1, is a ligand for RAGE. It has been shown that S100A12 induces adhesion molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe62696fe8003b1b263a1012ddad611
https://doi.org/10.1210/jc.2003-032223
https://doi.org/10.1210/jc.2003-032223
Autor:
Yasuaki Kijima, Toshiko Tokoro, Atsushi Kosaki, Yasukiyo Mori, Toshiji Iwasaka, Atsuko Nose, Hideki Yamahara, Mitsuhiko Okigaki, Takashi Nishiue, Noriko Kishimoto
Publikováno v:
Hypertension Research. 27:345-349
An increase in renal blood flow with a concomitant decrease in filtration fraction at the onset of angiotensin II receptor blocker treatment has been shown to predict a long-term renoprotective effect. However, no studies are available regarding angi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66697378dbca6b5ac8450e9883856fd8
https://doi.org/10.1291/hypres.27.345
https://doi.org/10.1291/hypres.27.345
Autor:
Megumi Inoue-Shibata, Yasukiyo Mori, Takamasa Hasegawa, Nagaoki Toyoda, Hiroya Masaki, Yutaka Kimura, Hiroaki Matsubara, Toshiji Iwasaka, Mitsuhiko Okigaki, Mitsushige Nishikawa, Atsushi Kosaki, Tatsuji Kimura
Publikováno v:
Atherosclerosis. 171:211-218
EN-RAGE is a ligand for the receptor for advanced glycation end products (RAGE) and may be involved in the development of diabetic macro- and micro-angiopathy. This study is designed to investigate the regulation of EN-RAGE gene expression in human m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d746895303f0c366fe10d7a04bb6af2
https://doi.org/10.1016/j.atherosclerosis.2003.08.021
https://doi.org/10.1016/j.atherosclerosis.2003.08.021
Autor:
Toshiji Iwasaka, Noriko Kishimoto, Atsushi Kosaki, Shigeki Higashiyama, Yasukiyo Mori, Katsuya Amano, Hiroaki Matsubara, Yoko Uchiyama-Tanaka
Publikováno v:
Kidney International. 62:799-808
Involvement of HB-EGF and EGF receptortransactivation in TGF-β–mediated fibronectin expression in mesangial cells. Background Gq-coupled receptors are known to transactivate epidermal growth factor receptor (EGFR) via the Ca2+ and PKC pathways to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2e17e3bf9276f627727f388e97f79b
https://doi.org/10.1046/j.1523-1755.2002.00537.x
https://doi.org/10.1046/j.1523-1755.2002.00537.x
Autor:
Clara Nahmias, Takamasa Hasegawa, Yoshihisa Nozawa, Soichiro Fujiyama, Osamu Iba, Toshiji Iwasaka, Atsushi Kosaki, Hiroaki Matsubara, Yasukiyo Mori, Eriko Tateishi, Atsuko Nose, Masatsugu Horiuchi, Hiroya Masaki, Yoko Uchiyama, Yasunobu Shibasaki, Yoshiaki Tsutsumi
Publikováno v:
Hypertension. 38:367-372
Angiotensin (Ang) II has 2 major receptor isoforms, Ang type 1 (AT 1 ) and Ang type (AT 2 ). AT 1 transphosphorylates epidermal growth factor receptor (EGFR) to activate extracellular signal–regulated kinase (ERK). Although AT 2 was shown to inacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086eefa67979d6b55c90cc6f1a645cbe
https://doi.org/10.1161/01.hyp.38.3.367
https://doi.org/10.1161/01.hyp.38.3.367
Autor:
Atsushi Kosaki, Yasukiyo Mori, Eriko Tateishi, Osamu Iba, Mitsuhiko Okigaki, Soichiro Fujiyama, Hiroaki Matsubara, Toshiji Iwasaka, Yasunobu Shibasaki, Atsuko Nose, Hiroya Masaki, Yoshiaki Tsutsumi, Masatsugu Horiuchi, Takamasa Hasegawa, Yoko Uchiyama, Clara Nahmias
Publikováno v:
Biochemical and Biophysical Research Communications. 282:1085-1091
Angiotensin II (Ang II) has two major receptor isoforms, AT1 and AT2. AT1 transphosphorylates Ca2+-sensitive tyrosine kinase Pyk2 to activate c-Jun NH2-terminal kinase (JNK). Although AT2 inactivates extracellular signal-regulated kinase (ERK) via ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b018ed50baf30650eb515fd7dcbfcf9
https://doi.org/10.1006/bbrc.2001.4695
https://doi.org/10.1006/bbrc.2001.4695
Autor:
Soichiro Fujiyama, Yasunobu Shibasaki, Toshiji Iwasaka, Atsuko Nose, Osamu Iba, Eriko Tateishi, Mitsuhiko Okigaki, Takamasa Hasegawa, Hiroya Masaki, Atsushi Kosaki, Yasukiyo Mori, Katsuya Amano, Hiroaki Matsubara, Yoko Tanaka-Uchiyama
Publikováno v:
Hypertension Research. 24:359-363
Hypertension accelerates the progression of renal disease in patients with chronic renal failure. Doxazosin, an alpha1-antagonist, is an antihypertensive agent with a long half-life. In this study, 15 patients with chronic renal failure were treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c4863c05e18ff5465ac6d85f322b68
https://doi.org/10.1291/hypres.24.359
https://doi.org/10.1291/hypres.24.359