Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Atsushi Konishi"'
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 749-759 (2024)
Introduction: Neural crest cells (NCCs) are cell populations that originate during the formation of neural crest in developmental stages. They are characterized by their multipotency, self-renewal and migration potential. Given their ability to diffe
Externí odkaz:
https://doaj.org/article/532571a6926e45ea9b4488c6b4d6fa41
Autor:
Kenichiro Ito, Yoshihiko Matsuda, Ayako Mine, Natsuki Shikida, Kazutoshi Takahashi, Kyohei Miyairi, Kazutaka Shimbo, Yoshimi Kikuchi, Atsushi Konishi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Peptides composed of two or more tandemly linked macrocyclic peptides binding to growth factor/cytokine receptors (STaMPtides) are useful growth factor/cytokine mimetics. The peptides can be produced from bacterial cells and bioactivity is demonstrat
Externí odkaz:
https://doaj.org/article/e3514258ae28475cb08f88085c95e500
Autor:
Kenichiro Ito, Yoshihiko Matsuda, Ayako Mine, Kyohei Miyairi, Yoshimi Kikuchi, Atsushi Konishi
Publikováno v:
ChemBioChem. 24
The inhibition of protein-protein interactions (PPIs) is an effective approach for therapy. Owing to their large binding surface areas to target proteins, macrocyclic peptides are suitable molecules for PPI inhibition. In this study, we developed sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a5ca8f0b35d1b87ce5084944d8edab
https://doi.org/10.1002/cbic.202200599
https://doi.org/10.1002/cbic.202200599
Publikováno v:
Materials Today Sustainability. 22:100407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67e900367a428a9a0c7c252a72b1f24d
https://doi.org/10.1016/j.mtsust.2023.100407
https://doi.org/10.1016/j.mtsust.2023.100407
Publikováno v:
The Journal of Physical Chemistry C. 124:11499-11505
The interfacial postmodification of PdAg alloy nanoparticles (NPs) supported on TiO2 was performed, using the widely studied metal–organic framework ZIF-8. The resulting PdAg/TiO2@ZIF-8 enhanced th...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb822fa39cbd47fc0e9f7c510b37982d
https://doi.org/10.1021/acs.jpcc.0c02457
https://doi.org/10.1021/acs.jpcc.0c02457
Autor:
Bunzo Mikami, Kenji Kojima, Ikumi Kuze, Kosuke Fukatsu, Atsushi Konishi, Kanta Yokokawa, Kiyoshi Yasukawa, Kosaku Nishimura, Tetsuro Hisayoshi
Publikováno v:
Protein expression and purification. 113:44-50
Moloney murine leukemia virus reverse transcriptase (MMLV RT) contains fingers, palm, thumb, and connection subdomains as well as an RNase H domain. The DNA polymerase active site resides in the palm subdomain, and the RNase H active site is located
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb07d721d37120627358bc1f2de153a4
http://hdl.handle.net/2433/200910
http://hdl.handle.net/2433/200910
Autor:
Saori Takahashi, Atsushi Konishi, Mayu Shinomura, Shohei Sakuda, Kanta Yokokawa, Keishi Hata, Tetsuro Hisayoshi, Kiyoshi Yasukawa, Satoru Nirasawa, Kumi Kawaji, Ikumi Kuze, Eiichi Kodama
Publikováno v:
Journal of Natural Medicines. 69:432-440
Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) possesses two distinct enzymatic activities: those of RNA- and DNA-dependent DNA polymerases and RNase H. In the current HIV-1 therapy, all HIV-1 RT inhibitors inhibit the activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2c5fbd3482ec7e1e10df1635a6dbc1
https://doi.org/10.1007/s11418-015-0885-9
https://doi.org/10.1007/s11418-015-0885-9
Autor:
Ibuki Ueoka, Mikio Aoki, Atsushi Konishi, Hideki Yoshida, Toru Maeda, Hitoshi Kawashima, Masamitsu Yamaguchi, Mamiko Ozaki, Ryo Tanaka
Publikováno v:
Experimental neurology. 300
Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication and social interactions, as well as restricted, stereotyped patterns of behavior and interests. In addition, alterations in circadian sleep-wake rhythm are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74aea4fe7a16c01eba9c0416a537a7f
https://pubmed.ncbi.nlm.nih.gov/29092799
https://pubmed.ncbi.nlm.nih.gov/29092799
Autor:
Kanta Yokokawa, Luis Menéndez-Arias, Kiyoshi Yasukawa, Atsushi Konishi, Tetsuro Hisayoshi, Verónica Barrioluengo
Publikováno v:
Biochemical and biophysical research communications. 454(2):269-274
We have previously used site-directed mutagenesis to introduce basic residues (i.e., Arg; Lys) in the nucleic acid binding cleft of the Moloney murine leukemia virus reverse transcriptase (MMLV RT) in order to increase its template-primer (T/P) bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690276422e21a5b72df5ba36848b7e96
http://hdl.handle.net/2433/192759
http://hdl.handle.net/2433/192759
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 78:75-78
After thermal incubation at 48 °C for 10 min, single variants of Moloney murine leukemia virus reverse transcriptase, V433R and V433K in which a surface hydrophobic residue, Val433, was mutated, retained 55% of initial reverse transcription activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8eb11fc95c2b458dd40e358caf436f6
https://doi.org/10.1080/09168451.2014.877186
https://doi.org/10.1080/09168451.2014.877186