Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Atsushi Kameda"'
Autor:
Shuhei Yoshida, Shota Uehara, Noriyasu Kondo, Yu Takahashi, Shiho Yamamoto, Atsushi Kameda, Soichiro Kawagoe, Naoko Inoue, Masami Yamada, Norito Yoshimura, Yuki Tachibana
Publikováno v:
Journal of medicinal chemistry. 65(15)
Recent technological innovations have led to the development of methods for the rapid identification of high-affinity macrocyclic peptides for a wide range of targets; however, it is still challenging to achieve the desired activity and membrane perm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba652531dfa6662aa6e199d8127f390
https://pubmed.ncbi.nlm.nih.gov/35904556
https://pubmed.ncbi.nlm.nih.gov/35904556
Autor:
Hisataka Kobayashi, Mikako Ogawa, Hideo Takakura, Kazuhide Sato, Kimura Toshihiro, Yasuo Yoshikawa, Atsushi Kameda, Kohei Nakajima, Shindo Takayuki
Publikováno v:
Oncotarget
// Kohei Nakajima 1 , Toshihiro Kimura 1, 2, 4 , Hideo Takakura 1 , Yasuo Yoshikawa 3 , Atsushi Kameda 4 , Takayuki Shindo 4 , Kazuhide Sato 5 , Hisataka Kobayashi 5 and Mikako Ogawa 1, 6 1 Laboratory of Bioanalysis and Molecular Imaging, Graduate Sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3e1b44a39fd49a3d6e777c374941bb
https://doi.org/10.18632/oncotarget.25068
https://doi.org/10.18632/oncotarget.25068
Publikováno v:
Protein Science. 18:1592-1601
In patients with dialysis-related amyloidosis, β2-microglobulin (β2-m) is a major structural component of amyloid fibrils. It has been suggested that the partial unfolding of β2-m is a prerequisite to the formation of amyloid fibrils, and that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221bf4c9df85aa41af81b635486737d9
https://doi.org/10.1002/pro.179
https://doi.org/10.1002/pro.179
Autor:
Tadato Ban, Toru Kawakami, Hironobu Naiki, Yuji Goto, Daisaku Ozawa, Hisashi Yagi, Atsushi Kameda
Publikováno v:
Journal of Biological Chemistry. 284(2):1009-1017
This research was originally published in the Journal of Biological Chemistry. Daisaku Ozawa, Hisashi Yagi, Tadato Ban, Atsushi Kameda, Toru Kawakami, Hironobu Naiki and Yuji Goto. Destruction of Amyloid Fibrils of a β2-Microglobulin Fragment by Las
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321884156f93376abf0cdc703518df51
https://hdl.handle.net/11094/71288
https://hdl.handle.net/11094/71288
Publikováno v:
Journal of Molecular Biology. 382:1242-1255
Beta(2)-microglobulin (beta2-m), a protein responsible for dialysis-related amyloidosis, adopts a typical immunoglobulin domain fold with the N-terminal peptide bond of Pro32 in a cis isomer. The refolding of beta2-m is limited by the slow trans-to-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6965df1090a3ed9dafe998c56b8127b
https://doi.org/10.1016/j.jmb.2008.08.003
https://doi.org/10.1016/j.jmb.2008.08.003
Publikováno v:
Natural Computing. 7:287-298
DNA machines consisting of consecutive hairpins, which we have previously described, have various potential applications in DNA computation. In the present study, a 288-base DNA machine containing four consecutive hairpins was successfully constructe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f8ff602d5e71464b1728eb60637144
https://doi.org/10.1007/s11047-007-9035-y
https://doi.org/10.1007/s11047-007-9035-y
Autor:
Ken Komiya, Shigeyuki Yokoyama, Azuma Ohuchi, Masahito Yamamoto, Daisuke Kiga, Masami Hagiya, Kensaku Sakamoto, Atsushi Kameda
Publikováno v:
Biosystems. 83(1):18-25
Parallelism is one of the major advantages of molecular computation. A large number of data encoded in DNA molecules can be processed simultaneously by molecular biology techniques, although only a single set of instructions has been implemented in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007427131be77b0bdb50da233f824f84
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100542232
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100542232
Autor:
Masahito Yamamoto, Masami Hagiya, Azuma Ohuchi, Kensaku Sakamoto, Hiroki Uejima, Atsushi Kameda
Publikováno v:
Natural Computing. 4:103-126
In this paper, we propose a new architecture for a multi-state DNA machine whose conformation of repeated hairpin structures changes sequentially in response to input oligomers. As an application of the machine, we also propose molecular memory in wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a55fd0d85ae125f4224c2a7db4ecddb
https://doi.org/10.1007/s11047-004-4007-y
https://doi.org/10.1007/s11047-004-4007-y
Autor:
Takashi Higurashi, Satoshi Takahashi, Hironobu Naiki, Yuji Goto, Masaru Hoshino, Atsushi Kameda
Publikováno v:
Journal of Molecular Biology. 348:383-397
beta(2)-Microglobulin (beta2-m), a light chain of the major histocompatibility complex type I, is also found as a major component of amyloid fibrils formed in dialysis-related amyloidosis. Denaturation of beta2-m is considered to initiate the formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7669319472a77335ff0d03117229fb
https://doi.org/10.1016/j.jmb.2005.02.050
https://doi.org/10.1016/j.jmb.2005.02.050
Publikováno v:
Nucleic Acids Research
We have developed an algorithm for designing multiple sequences of nucleic acids that have a uniform melting temperature between the sequence and its complement and that do not hybridize non-specifically with each other based on the minimum free ener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5115e58467f513b15993951ac155f101
http://hdl.handle.net/2115/64504
http://hdl.handle.net/2115/64504