Zobrazeno 1 - 10 of 151 pro vyhledávání: '"Atsushi Irie"'
1
Akademický článek
Development of a single-chain variable antibody fragment against a conserved region of the SARS-CoV-2 spike protein
Autor: Tingyu Gao, Atsushi Irie, Takahisa Kouwaki, Hiroyuki Oshiumi
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has prolonged the duration of the pandemic because of the continuous emergence of new variant strains. The emergence of these mutant strains makes it difficult to detect the virus
Externí odkaz: https://doaj.org/article/1066ef35d55748979d992631ff7a94ca
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2
Akademický článek
Bladder cancer-associated cancer-testis antigen-derived long peptides encompassing both CTL and promiscuous HLA class II-restricted Th cell epitopes induced CD4+ T cells expressing converged T-cell receptor genes in vitro
Autor: Miki Tsuruta, Shohei Ueda, Poh Yin Yew, Isao Fukuda, Sachiko Yoshimura, Hiroyuki Kishi, Hiroshi Hamana, Masatoshi Hirayama, Junji Yatsuda, Atsushi Irie, Satoru Senju, Eiji Yuba, Tomomi Kamba, Masatoshi Eto, Hideki Nakayama, Yasuharu Nishimura
Publikováno v: OncoImmunology, Vol 7, Iss 4 (2018)
DEP domain containing 1 (DEPDC1) and M-phase phosphoprotein 1 (MPHOSPH1) are human cancer testis antigens that are frequently overexpressed in urinary bladder cancer. In a phase I/II clinical trial, a DEPDC1- and MPHOSPH1-derived short peptide vaccin
Externí odkaz: https://doaj.org/article/a381e4ac4ae24f4b8b66f97b7ddc00da
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3
Akademický článek
Establishment of HLA-DR4 transgenic mice for the identification of CD4+ T cell epitopes of tumor-associated antigens.
Autor: Junji Yatsuda, Atsushi Irie, Kumiko Harada, Yayoi Michibata, Hirotake Tsukamoto, Satoru Senju, Yusuke Tomita, Akira Yuno, Masatoshi Hirayama, Mohammad Abu Sayem, Naoki Takeda, Isao Shibuya, Shinji Sogo, Fumihiro Fujiki, Haruo Sugiyama, Masatoshi Eto, Yasuharu Nishimura
Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84908 (2013)
Reports have shown that activation of tumor-specific CD4(+) helper T (Th) cells is crucial for effective anti-tumor immunity and identification of Th-cell epitopes is critical for peptide vaccine-based cancer immunotherapy. Although computer algorith
Externí odkaz: https://doaj.org/article/19d69771287a45c68392bc06b1c0c833
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4
Akademický článek
Phosphorylation of SET protein at Ser171 by protein kinase D2 diminishes its inhibitory effect on protein phosphatase 2A.
Autor: Atsushi Irie, Kumiko Harada, Norie Araki, Yasuharu Nishimura
Publikováno v: PLoS ONE, Vol 7, Iss 12, p e51242 (2012)
We previously reported that protein kinase D2 (PKD2) in T cells is promptly activated after T-cell receptor (TCR) stimulation and involved in the activation of interleukin-2 promoter and T cell death, and that one of its candidate substrate is SET pr
Externí odkaz: https://doaj.org/article/7ca1c1b72db241a88613e2e55e0aa0c6
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