Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Atsushi Gondou"'
Autor:
Toshiko Tokoro, Toshinaga Yonemoto, Tamayo Kadobayashi, Atsushi Gondou, Yoshifumi Ogawa, Mitsushige Nishikawa, Noriko Sakaguchi, Yuko Imai, Mitsuo Inada, Sakuyoshi Tabata, Nagaoki Toyoda, Fangzheng Wang
Publikováno v:
Endocrine Journal. 46:497-504
We investigated the effects of streptozotocin (STZ)-induced diabetes on thyroid hormone levels, type 1 deiodinase (D1) activity and messenger RNA (mRNA) levels in inherited D1 deficient C3H mice in a comparative manner with control C57 mice. The appa
Autor:
Toshinaga Yonemoto, Yuko Imai, Yasukiyo Mori, Toshiji Iwasaka, Mitsuo Inada, Nagaoki Toyoda, Hiroaki Matsubara, Mitsushige Nishikawa, Atsushi Gondou
Publikováno v:
Endocrine Journal. 46:621-628
We previously demonstrated that iodothyronine 5'-deiodination (5'D) activity is present and increased by triiodothyronine (T3) and angiotensin II (Ang II) in cultured rat cardiac myocytes. To further elucidate the stimulatory mechanism of Ang II, we
Autor:
Toshiko Tokoro, Sakuyoshi Tabata, Atsushi Gondou, Mitsuo Inada, Toshinaga Yonemoto, Noriko Sakaguchi, Mitsushige Nishikawa, Masayoshi Yoshimura, Norio Yoshikawa, Nagaoki Toyoda, Yoshifumi Ogawa
Publikováno v:
Biochemical and Biophysical Research Communications. 250:642-646
To evaluate the regulatory mechanism of human Type 1 iodothyronine deiodinase (D1) gene expression, we measured the D1 mRNA levels in peripheral blood mononuclear cells (PBMC) in normal control subjects and in patients with Graves' disease. We used c
Autor:
Tsutomu Kato, Toshinaga Yonemoto, Masayoshi Yoshimura, Mitsuo Inada, Toshihito Furumura, Nagaoki Toyoda, Mitsushige Nishikawa, Hiroaki Kurokawa, Hiroya Masaki, Atsushi Gondou
Publikováno v:
Acta Endocrinologica. 129:213-219
To evaluate the relationship between eye changes and autoantibody to the thyrotropin receptor in patients with Graves' disease, we evaluated the eye changes using magnetic resonance imaging and the results were correlated with thyroid-stimulating ant
Autor:
Yasukiyo Mori, Y. Ogawa, Nagaoki Toyoda, Mitsuo Inada, Atsushi Gondou, Mitsushige Nishikawa, Toshinaga Yonemoto, Hiroya Masaki, Masayoshi Yoshimura
Publikováno v:
Endocrinology. 131:389-394
We investigated the regulation of type I iodothyronine 5'-deiodinase (5'-D) gene expression by TSH and T3 in FRTL-5 rat thyroid cells. Northern blot analysis revealed that these cells express a 5'-D messenger RNA (mRNA) species of 2.1 kilobases. Read
Autor:
Toshinaga Yonemoto, Mitsushige Nishikawa, Noriko Sakaguchi, Toshiko Tokoro, Atsushi Gondou, Mitsuo Inada, Nagaoki Toyoda
Publikováno v:
Endocrine journal. 46(1)
Intracellular generation of triiodothyronine (T3) from thyroxine (T4) by type 2 deiodinase (D2) in the mammalian brain, plays a key role in thyroid hormone action. The presence of D2 in rat astrocytes suggests the importance of glial cells in the reg
Autor:
Y. Ogawa, Toshinaga Yonemoto, Mitsushige Nishikawa, Nagaoki Toyoda, Atsushi Gondou, Mitsuo Inada
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 31(5)
To evaluate the age- and sex-related changes in Type 1 iodothyronine deiodinase gene expression in the liver and kidneys, we measured 5'-deiodinating activity and deiodinase mRNA in developing rats. The activity in the liver increased after birth, an
Autor:
Yoshifumi Ogawa, Toshiko Tokoro, Atsushi Gondou, Fangzheng Wang, Noriko Sakaguchi, Mitsushige Nishikawa, Mitsuo Inada, Toshinaga Yonemoto, Sakuyoshi Tabata, Nagaoki Toyoda
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 8(7)
We investigated the effects of cyclic guanosine 3',5'-monophosphate (cGMP) on type 2 iodothyronine deiodinase (D2) in cultured rat glial cells. Rat glial cells were cultured in Dulbecco's modified Eagle's medium supplemented with 15% fetal bovine ser
Autor:
S. Tabata, Toshinaga Yonemoto, Y. Ogawa, H. Shimizu, A. Shouzu, M. Kanasaki, Mitsuo Inada, M. Hikosaka, Y. Miyake, Mitsushige Nishikawa, Atsushi Gondou
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 27(8)
A nine-year old boy developed reduced growth velocity at the age of seven. The peak plasma growth hormone (GH) response to 3,4-dihydroxyphenylalanine, GH-releasing factor and insulin was 10.2, 8.1 and 7.6 micrograms/l, respectively, suggesting that t