Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Atsushi Fukumura"'
Autor:
Nobuyuki Toshikuni, Mutsumi Tsuchishima, Atsushi Fukumura, Tomiyasu Arisawa, Mikihiro Tsutsumi
Publikováno v:
Gastroenterology Research and Practice, Vol 2017 (2017)
Alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH) are representative types of fatty liver disease (FLD) and have similar histologic features. In this study, we aimed to compare the associations of the two FLD types with hyperten
Externí odkaz:
https://doaj.org/article/0a189e815bd0442cb8340364a78bd72b
Autor:
Nobuhiko Hayashi, Joseph George, Masayoshi Takeuchi, Atsushi Fukumura, Nobuyuki Toshikuni, Tomiyasu Arisawa, Mikihiro Tsutsumi
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70034 (2013)
Chronic ingestion of ethanol increases acetaldehyde and leads to the production of acetaldehyde-derived advanced glycation end-products (AA-AGE). We evaluated the toxicity of AA-AGE on hepatocytes and studied the role of AA-AGE in the pathogenesis of
Externí odkaz:
https://doaj.org/article/ba6218d6dfa84ee9a2a84096e78961aa
Autor:
Atsushi Fukumura, Kazuyuki Sogawa, Fumio Nomura, Masanori Seimiya, Shigeo Sueyoshi, Setsu Sawai, Mikihiro Tsutsumi, Mamoru Satoh
Publikováno v:
World Journal of Hepatology
AIM To assess how serum gamma-glutamyltransferase (GGT) fractions vary in patients with alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). METHODS Serum samples were obtained from 14 patients with biopsy-proven alcoholic liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6f7107e691d0dfb585a97006957a5f
http://europepmc.org/articles/PMC5192552
http://europepmc.org/articles/PMC5192552
Publikováno v:
Gastroenterology. 158:S-1340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b92b09356cb7cc36a40e5384ced3cb
https://doi.org/10.1016/s0016-5085(20)34019-1
https://doi.org/10.1016/s0016-5085(20)34019-1
Autor:
Nobuhiko Hayashi, Joseph George, Yoshimichi Ueda, Nobuyuki Toshikuni, Yuki Hirakawa, Mutsumi Tsuchishima, Atsushi Fukumura, Mikihiro Tsutsumi, Takashi Saito, Kaori Kinoshita
Publikováno v:
European Journal of Pharmacology. 863:172681
Recombinant thrombomodulin (rTM) is a novel anticoagulant and anti-inflammatory agent that inhibits secretion of high-mobility group box 1 (HMGB1) from liver. We evaluated the protective effects of rTM on hepatic ischemia-reperfusion injury in rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec38b93ce095767bde13e59f7fb3d307
https://doi.org/10.1016/j.ejphar.2019.172681
https://doi.org/10.1016/j.ejphar.2019.172681
Autor:
Joseph George, Mikihiro Tsutsumi, Atsushi Fukumura, Kazuaki Ozaki, Nobuyuki Toshikuni, Mutsumi Tsuchishima
Publikováno v:
Gastroenterology. 156:S-1314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::439c4c94535bc9d10965c27e2732ad12
https://doi.org/10.1016/s0016-5085(19)40300-4
https://doi.org/10.1016/s0016-5085(19)40300-4
Autor:
Takahiro Minato, Tomomitsu Tahara, Yasuhito Matsue, Hideto Yamada, Tomoyuki Shibata, Tomoe Nomura, Masakatsu Nakamura, Atsushi Fukumura, Kazuhiro Matsunaga, Nobuhiko Hayashi, Tomiyasu Arisawa, Hisakazu Shiroeda, Ranji Hayashi, Takashi Saito, Tomoki Fukuyama, Toshimi Otsuka
Publikováno v:
Human Immunology. 73:747-752
We report an association between gastric cancer (GC) and polymorphisms in IL17A, rs2275913 (-197 GA), rs3748067 (*1249 CT), and pri-miR-938, rs2505901 (TC). We employed the multiplex PCR-SSCP method to detect gene polymorphisms in 337 GC cases and 58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e8cd04d75a60c67c873c8a09f1cb97
https://doi.org/10.1016/j.humimm.2012.04.011
https://doi.org/10.1016/j.humimm.2012.04.011
Autor:
Yasuhiro Matsue, Takahiro Minato, Tomomitsu Tahara, Hisakazu Shiroeda, Masakatsu Nakamura, Tomoyuki Shibata, Tomiyasu Arisawa, Takashi Saito, Tomoki Fukuyama, Atsushi Fukumura, Toshimi Otsuka
Publikováno v:
Journal of Gastroenterology. 48:73-80
Visceral sensory impulses are transmitted via C-fibers from the gastrointestinal tract to the central nervous system. The tetrodotoxinresistant (TTX-r) sodium channel, Na(V) 1.8/SNS (sensory-neuron specific), encoded by SCN10A, has been identified on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193993886b60c3008f79925ec22b5f80
https://doi.org/10.1007/s00535-012-0602-3
https://doi.org/10.1007/s00535-012-0602-3
Autor:
Nobuhiko Hayashi, Masayuki Fukura, Shujiro Takase, Hirokazu Yano, Mikihiro Tsutsumi, Atsushi Fukumura, Kazuaki Ozaki, Mutsumi Tsuchishima
Publikováno v:
Alcoholism: Clinical and Experimental Research. 31:S49-S53
Background: Recently, ME3738, a derivative of soyasapogenol B, was developed as an inducer of interleukin (IL)-6. It has been demonstrated that ME3738 is stimulate to produce IL-6 and that it protects against concanavalin A-induced liver failure. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850c4fb27c90d45013bd25685ec264fb
https://doi.org/10.1111/j.1530-0277.2006.00286.x
https://doi.org/10.1111/j.1530-0277.2006.00286.x
Autor:
Nobuhiko, Hayashi, Takashi, Saito, Masahiro, Kakuda, Yasuhiro, Matsue, Takashiro, Minato, Atsushi, Fukumura, Kazuaki, Ozaki, Mutsumi, Tsuchisima, Mikihiro, Tsutsumi
Publikováno v:
Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studiesdrug dependence. 49(5)
In 1983, Nei et al. reported that alcoholic chronic hepatitis (ACH)(chronic hepatitis induced tal area. Recently, the number of alcoholics patients diagnosed with ACH has been increased In this review, we discussed the characteristics of liver histop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fa2f526f5745f37a0845e10963f8076
https://pubmed.ncbi.nlm.nih.gov/25651616
https://pubmed.ncbi.nlm.nih.gov/25651616