Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Atsushi Hijikata"'
Autor:
Kohdai Yamada, Ryouhei Shioya, Kohei Nishino, Hirotake Furihata, Atsushi Hijikata, Mika K. Kaneko, Yukinari Kato, Tsuyoshi Shirai, Hidetaka Kosako, Tatsuya Sawasaki
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Receptor proteins, such as epidermal growth factor receptor (EGFR), interact with other proteins in the extracellular region of the cell membrane to drive intracellular signalling. Therefore, analysis of extracellular protein-protein interac
Externí odkaz:
https://doaj.org/article/e1786466eff242848bf775caca410fb3
Autor:
Tatsuro Nishikino, Atsushi Hijikata, Seiji Kojima, Tsuyoshi Shirai, Masatsune Kainosho, Michio Homma, Yohei Miyanoiri
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107320- (2023)
Summary: The FliG protein plays a pivotal role in switching the rotational direction of the flagellar motor between clockwise and counterclockwise. Although we previously showed that mutations in the Gly-Gly linker of FliG induce a defect in switchin
Externí odkaz:
https://doaj.org/article/15cd86dea7094e08a0eb72e4041528dd
Autor:
Hiroki Miyauchi, Tomoharu Ishikawa, Yutaro Hirakawa, Ayumu Sudou, Katsuhiko Okada, Atsushi Hijikata, Norihiro Sato, Mikio Tsuzuki, Shoko Fujiwara
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Attached culture allows high biomass productivity and is a promising biomass cultivating system because neither a huge facility area nor a large volume of culture medium are needed. This study investigates photosynthetic and transcriptomic behaviors
Externí odkaz:
https://doaj.org/article/ea3735a6937048a7abd30ba047621d45
Autor:
Kana Unuma, Dan Tomomasa, Kosuke Noma, Kouhei Yamamoto, Taka-aki Matsuyama, Yohsuke Makino, Atsushi Hijikata, Shuheng Wen, Tsutomu Ogata, Nobuhiko Okamoto, Satoshi Okada, Kenichi Ohashi, Koichi Uemura, Hirokazu Kanegane
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Herein, we report a child with COVID-19 and seemingly no underlying disease, who died suddenly. The autopsy revealed severe anemia and thrombocytopenia, splenomegaly, hypercytokinemia, and a rare ectopic congenital coronary origin. Immunohistochemica
Externí odkaz:
https://doaj.org/article/3810d0a8a0a54586b1fdf9e9adfad421
Autor:
Atsushi Hijikata, Clara Shionyu‐Mitsuyama, Setsu Nakae, Masafumi Shionyu, Motonori Ota, Shigehiko Kanaya, Takatsugu Hirokawa, Shogo Nakajima, Koichi Watashi, Tsuyoshi Shirai
Publikováno v:
FEBS Open Bio, Vol 12, Iss 1, Pp 285-294 (2022)
Cepharanthine (CEP) is a natural biscoclaurine alkaloid of plant origin and was recently demonstrated to have anti‐severe acute respiratory syndrome coronavirus 2 (anti‐SARS‐CoV‐2) activity. In this study, we evaluated whether natural analogu
Externí odkaz:
https://doaj.org/article/107db267d382427094cc9f1a9c93c0be
Autor:
Maki Gau, Ryota Suga, Atsushi Hijikata, Ayako Kashimada, Masatoshi Takagi, Ryuichi Nakagawa, Kei Takasawa, Tsuyoshi Shirai, Kenichi Kashimada, Tomohiro Morio
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionNR5A1 and NR5A2 belong to an orphan nuclear receptor group, and approximately 60% of their amino acid sequences are conserved. Transcriptional regulation of NR5A receptors depends on interactions with co-factors or unidentified ligands.Pu
Externí odkaz:
https://doaj.org/article/035141c10a734bc786d2ea6ea7642a0f
Autor:
Takafumi Hara, Ikuko Yamada, Takuto Ohashi, Masaru Tamura, Atsushi Hijikata, Takashi Watanabe, Minghao Gao, Kana Ito, Saeko Kawamata, Shiori Azuma, Emi Yoshigai, Yukiko Sumiyoshi, Natsumi Yasuhiro, Osamu Ohara, Heloísa G Dos Santos, Toshiyuki Fukada
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0276452 (2022)
Zinc plays a critical role in many physiological processes, and disruption of zinc homeostasis induces various disorders, such as growth retardation, osteopenia, immune deficiency, and inflammation. However, how the imbalance in zinc homeostasis lead
Externí odkaz:
https://doaj.org/article/fe8a6be096984458be8a07a08c403147
Current status of structure-based drug repurposing against COVID-19 by targeting SARS-CoV-2 proteins
Autor:
Atsushi Hijikata, Clara Shionyu, Setsu Nakae, Masafumi Shionyu, Motonori Ota, Shigehiko Kanaya, Tsuyoshi Shirai
Publikováno v:
Biophysics and Physicobiology, Vol 18 (2021)
More than one and half years have passed, as of August 2021, since the COVID-19 caused by the novel coronavirus named SARS-CoV-2 emerged in 2019. While the recent success of vaccine developments likely reduces the severe cases, there is still a stron
Externí odkaz:
https://doaj.org/article/f3e93de53051417d91e2241d78485984
Autor:
Takahiro Hayashi, Naoko Yano, Kengo Kora, Atsushi Yokoyama, Kanako Maizuru, Taisei Kayaki, Kinuko Nishikawa, Mitsujiro Osawa, Akira Niwa, Toshiki Takenouchi, Atsushi Hijikata, Tsuyoshi Shirai, Hisato Suzuki, Kenjiro Kosaki, Megumu K Saito, Junko Takita, Takeshi Yoshida
Publikováno v:
Human Molecular Genetics. 32:1683-1697
Membrane fusion is mediated by soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins. During neurotransmitter exocytosis, SNARE proteins on a synaptic vesicle and the target membrane form a complex, resulting in neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::257be24fd916a740a6be0fef85c0a5fa
https://doi.org/10.1093/hmg/ddad008
https://doi.org/10.1093/hmg/ddad008
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The inheritance modes of pathogenic missense mutations are known to be highly associated with protein structures; recessive mutations are mainly observed in the buried region of protein structures, whereas dominant mutations are significantl
Externí odkaz:
https://doaj.org/article/f36a28c1ef944b89891155264aaa0f6e