Zobrazeno 1 - 10
of 597
pro vyhledávání: '"Atsushi, Nakagawa"'
Publikováno v:
eLife, Vol 12 (2024)
Kinesin-3 is a family of microtubule-dependent motor proteins that transport various cargos within the cell. However, the mechanism underlying kinesin-3 activations remains largely elusive. In this study, we compared the biochemical properties of two
Externí odkaz:
https://doaj.org/article/72133c87b7da432497a7f49c366bcb89
Autor:
Ryosuke Hirabayashi, Kazuma Nagata, Yuki Sato, Atsushi Nakagawa, Ryo Tachikawa, Hirokazu Kuroda, Ryutaro Seo, Takeshi Morimoto, Keisuke Tomii
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background High-flow nasal cannula (HFNC) therapy is an important non-invasive respiratory support in acute respiratory failure, including coronavirus disease (COVID-19) pneumonia. Although the respiratory rate and oxygenation (ROX) index is
Externí odkaz:
https://doaj.org/article/38921cc1fd7a4c32a6e7e792b42b7446
Autor:
Ryo Tamura, Kei Irie, Atsushi Nakagawa, Hirohito Muroi, Masaaki Eto, Hiroaki Ikesue, Nobuyuki Muroi, Shoji Fukushima, Keisuke Tomii, Tohru Hashida
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 4, Pp 513-521 (2023)
Abstract Although remdesivir, a prodrug of nucleoside analog (GS‐441524), has demonstrated clinical benefits in coronavirus disease 2019 (COVID‐19) treatment, its pharmacokinetics (PKs) in patients with COVID‐19 remain poorly understood. Theref
Externí odkaz:
https://doaj.org/article/81089085c39e4fd985767e9beedfdef0
Autor:
Takehiro Hasegawa, Maho Yoshida, Shunsuke Watanabe, Takami Kondo, Hideo Asada, Atsushi Nakagawa, Keisuke Tomii, Masami Kameda, Mitsuo Otsuka, Koji Kuronuma, Hirofumi Chiba, Shinji Katayanagi, Yasunari Miyazaki, Akio Mori
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract C–X–C motif chemokine ligand 9 (CXCL9), a candidate biomarker, reflects type 1 (T1) inflammation pathology. Here, we report the analytical performance and clinical characteristics of a new CXCL9 reagent for a fully automated immunoassay
Externí odkaz:
https://doaj.org/article/b5c2351e97f44236b2a89fcb5a634f70
Autor:
Ken-ichi Harada, Kyoko Furuita, Eiki Yamashita, Ken-ichiro Taoka, Hiroyuki Tsuji, Toshimichi Fujiwara, Atsushi Nakagawa, Chojiro Kojima
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract In potato (Solanum tuberosum L.), 14-3-3 protein forms a protein complex with the FLOWERING LOCUS T (FT)-like protein StSP6A and the FD-like protein StFDL1 to activate potato tuber formation. Eleven 14-3-3 isoforms were reported in potato, d
Externí odkaz:
https://doaj.org/article/0f9d64f41ed14723a832c4932a14ea11
Autor:
Takahiro Ando, Sho Shimada, Jun Sugihara, Koji Takayama, Masayoshi Kobayashi, Yoshihiro Miyashita, Tatsuya Ito, Kaori Okayasu, Shun Tsuyuki, Takehiko Ohba, Masafumi Doi, Hiroaki Saito, Toshihide Fujie, Tomoshige Chiaki, Atsushi Nakagawa, Tatsuhiko Anzai, Kunihiko Takahashi, Sho Shibata, Tomoya Tateishi, Yasunari Miyazaki
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 24, p 7640 (2023)
The post-acute sequelae of SARS-CoV-2 (PASC) pose a threat to patients’ health-related quality of life (HRQOL). Here, the impact of COVID-19 on HRQOL and the clinical factors associated with impaired HRQOL were examined. Discharged COVID-19 patient
Externí odkaz:
https://doaj.org/article/c9e266784e48435c9fb48c045a59f17f
Autor:
Kota Ichimaru, Koji Yamaguchi, Kenichi Harada, Yusaku Nishio, Momoka Hori, Kazuya Ishikawa, Haruhiko Inoue, Shusuke Shigeta, Kento Inoue, Keita Shimada, Satomi Yoshimura, Takumi Takeda, Eiki Yamashita, Toshimichi Fujiwara, Atsushi Nakagawa, Chojiro Kojima, Tsutomu Kawasaki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The U-box type ubiquitin ligase PUB44 positively regulates pattern-triggered immunity in rice. Here the authors identify a PUB44 substrate whose degradation is required for activation of the WRKY45 transcription factor upon immune elicitation.
Externí odkaz:
https://doaj.org/article/fcad8a8fb12941a18aad7aa53f62554a
Publikováno v:
IEEE Access, Vol 10, Pp 108354-108365 (2022)
Despite constant advances in X-ray crystallography, the resolution of the acquired electron density maps still poses a serious limit on protein protein structural model building efforts. Furthermore, the currently available toolkits require hours or
Externí odkaz:
https://doaj.org/article/c3bc03a2c14043739bfb4fe16d697c13
Publikováno v:
IEEE Access, Vol 10, Pp 28760-28772 (2022)
This work proposes a neural network architecture, called 3D FC-DenseNet, for assigning amino acid labels to X-ray crystallographic electron density maps without relying on the amino acid sequence of proteins. The 3DFC-DenseNet is able to treat the ta
Externí odkaz:
https://doaj.org/article/71d2a18b17fe4e1f94e5679ee017e7e6
Autor:
Masahiro Shirata, Isao Ito, Tadashi Ishida, Hiromasa Tachibana, Naoya Tanabe, Satoshi Konishi, Issei Oi, Nobuyoshi Hamao, Kensuke Nishioka, Hisako Matsumoto, Yoshiro Yasutomo, Seizo Kadowaki, Hisashi Ohnishi, Hiromi Tomioka, Takashi Nishimura, Yoshinori Hasegawa, Atsushi Nakagawa, Toyohiro Hirai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The discriminative power of CURB-65 for mortality in community-acquired pneumonia (CAP) is suspected to decrease with age. However, a useful prognostic prediction model for older patients with CAP has not been established. This study aimed t
Externí odkaz:
https://doaj.org/article/194a71883d344596abc4fab0a1b22dc4