Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Atsushi, Fukunari"'
Autor:
Hiroaki Matsushita, Atsushi Fukunari, Gento Sameshima, Masamitsu Okada, Fumika Inoue, Mitsuharu Ueda, Yukio Ando
Publikováno v:
Journal of Radiation Research and Applied Sciences, Vol 15, Iss 4, Pp 100484- (2022)
Ultraviolet (UV) irradiation originating in the space environment has been increasing because of the destruction of the ozone layer. Although UV irradiation damages DNA, peptides, and cell structures, it also has the beneficial effects of suppressing
Externí odkaz:
https://doaj.org/article/f75388699a2a4ae998b62cbef7aed40c
Publikováno v:
Biology, Vol 12, Iss 2, p 320 (2023)
The MATP/tau protein is hyperphosphorylated in Alzheimer’s patients. Therefore, research into the regulation of tau protein phosphorylation is important for understanding Alzheimer’s disease. HASPIN is a serine/threonine kinase that is expressed
Externí odkaz:
https://doaj.org/article/94ba20f9ae994c44b2e3fba721281c4d
Autor:
Tomoaki Tezuka, Makoto Tamura, Mari A. Kondo, Masaki Sakaue, Kinya Okada, Kana Takemoto, Atsushi Fukunari, Keiko Miwa, Hiromitsu Ohzeki, Shin-ichi Kano, Hiroshi Yasumatsu, Akira Sawa, Yasushi Kajii
Publikováno v:
Neurobiology of Disease, Vol 59, Iss , Pp 63-68 (2013)
A growing body of evidence suggests the involvement of inflammatory processes in the pathophysiology of schizophrenia. Four- to 8-week exposure to cuprizone, a copper chelator, causes robust demyelination and has been used to build a model for multip
Externí odkaz:
https://doaj.org/article/2e50a9f739bd4422b7c604af697524e3
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 3, Pp 314-320 (2006)
Clinically, hemorrhoidal bleeding and prolapse disappeared immediately after injection of the sclerosing agent OC-108 into submucosa of hemorrhoids. The aim of this study was to elucidate the mechanism of action responsible for the immediate hemostat
Externí odkaz:
https://doaj.org/article/f198d975cb9544c7a896185561a72690
Autor:
Kinya Okada, Hiroyuki Utsumi, Tetsuhiro Kakimoto, Atsushi Fukunari, Keisuke Fujitaka, Masashi Nishio, Tsuyoshi Kato
Publikováno v:
Experimental and Toxicologic Pathology. 67:171-177
Podocytes are an essential component of the renal glomerular filtration barrier, their injury playing an early and important role in progressive renal dysfunction. This makes quantification of podocyte marker immunoreactivity important for early dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0ff3bd9bb7bb368bcbd7d2b57892df
https://doi.org/10.1016/j.etp.2014.11.007
https://doi.org/10.1016/j.etp.2014.11.007
Autor:
Kinya Okada, Hiroyuki Utsumi, Yoshihiro Hirohashi, Mizue Kawai, Keisuke Fujitaka, Tsuyoshi Kato, Raissa Relator, Atsushi Fukunari, Tetsuhiro Kakimoto, Taku Iguchi, Masashi Nishio
Publikováno v:
Journal of Endocrinology. 222:43-51
Diabetic nephropathy is a major complication in diabetes and a leading cause of end-stage renal failure. Glomerular podocytes are functionally and structurally injured early in diabetic nephropathy. A non-obese type 2 diabetes model, the spontaneousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1793d49469abf894c2717754c29dcc
https://doi.org/10.1530/joe-14-0164
https://doi.org/10.1530/joe-14-0164
Autor:
Kenji Chiba, Hiroyuki Utsumi, Kunio Sugahara, Atsushi Fukunari, Yasuhiro Maeda, Kana Takemoto, Takashi Masuko, Hideki Yagi
Publikováno v:
International Immunology. 26:245-255
Sphingosine 1-phosphate (S1P) and S1P receptor 1 (S1P1) play an important role in the egress of mature CD4 or CD8 single-positive (SP) thymocytes from the thymus. Fingolimod hydrochloride (FTY720), an S1P1 functional antagonist, induced significant a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae21b3669c6afe3152f624154c2df8c
https://doi.org/10.1093/intimm/dxt069
https://doi.org/10.1093/intimm/dxt069
Publikováno v:
Pharmacology & Pharmacy. :638-646
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::150f23caf6a98141576d053ca76d6840
https://doi.org/10.4236/pp.2013.48090
https://doi.org/10.4236/pp.2013.48090
Autor:
Kunio Sugahara, Atsushi Fukunari, Mamoru Koyama, Hirotoshi Kataoka, Noriyasu Seki, Takahisa Sugita, Kyoko Shimano, Kenji Chiba
Publikováno v:
International Immunopharmacology. 11:366-372
Fingolimod (FTY720), a sphingosine 1-phosphate (S1P) receptor modulator, inhibits S1P-dependent lymphocyte egress from secondary lymphoid organs and is highly effective in experimental autoimmune encephalomyelitis (EAE) in mice. In this study, we dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e13d9c9da56a980498928fccead5e6f
https://doi.org/10.1016/j.intimp.2010.10.005
https://doi.org/10.1016/j.intimp.2010.10.005
Autor:
Atsushi Fukunari, Kenji Chiba, Hirotoshi Kataoka, Kyoko Shimano, Yasuhiro Maeda, Takahisa Sugita, Mamoru Koyama, Kunio Sugahara, Noriyasu Seki
Publikováno v:
Inflammation and Regeneration. 30:451-457
Experimental autoimmune encephalomyelitis (EAE) is a CD4 T cell-mediated disease model for multiple sclerosis (MS). When SJL/J mice are immunized with myelin proteolipid protein (PLP), EAE symptoms were developed within 2 weeks, remitted thereafter,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317e3367a83a9b22201db3ec165cafa0
https://doi.org/10.2492/inflammregen.30.451
https://doi.org/10.2492/inflammregen.30.451